Test Bank For Basic Pharmacology for Nurses 17th Edition by Michelle Willihnganz,
Bruce D. Clayton Chapter 1-48
TABLE OF CONTENTS.
Unit 1: Applying Pharmacology to Nursing Practice
Chapter 1: Drug Definitions, Standards, and Information Sources
Chapter 2: Basic Principles of Drug Action and Drug Interactions
Chapter 3: Drug Action Across the Life Span
Chapter 4: The Nursing Process and Pharmacology
Chapter 5: Patient Education to Promote Health
Unit 2: Illustrated Atlas of Medication Administration
Chapter 6: Principles of Medication Administration and Medication Safety
Chapter 7: Percutaneous Administration
Chapter 8: Enteral Administration
Chapter 9: Parenteral Administration: Safe Preparation of Parenteral Medications
Chapter 10: Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
Routes
Chapter 11: Parenteral Administration: Intravenous Route
Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems
Chapter 12: Drugs Affecting the Autonomic Nervous System
Chapter 13: Drugs Used for Sleep
Chapter 14: Drugs Used for Neurodegenerative Disorders (NEW!)
Chapter 15: Drugs Used for Anxiety Disorders
Chapter 16: Drugs Used for Depressive and Bipolar Disorders
Chapter 17: Drugs Used for Psychoses
Chapter 18: Drugs Used for Seizure Disorders
Chapter 19: Drugs Used for Pain Management
Unit 4: Drugs Affecting the Cardiovascular System
Chapter 20: Introduction to Cardiovascular Disease and Metabolic Syndrome
Chapter 21: Drugs Used to Treat Dyslipidemias
Chapter 22: Drugs Used to Treat Hypertension
Chapter 23: Drugs Used to Treat Dysrhythmias
Chapter 24: Drugs Used to Treat Angina Pectoris
Chapter 25: Drugs Used to Treat Peripheral Vascular Disease
Chapter 26: Drugs Used to Treat Thromboembolic Disorders
Chapter 27: Drugs Used to Treat Heart Failure
Chapter 28: Drugs Used for Diuresis
Unit 5: Drugs Affecting the Respiratory System
Chapter 29: Drugs Used to Treat Upper Respiratory Disease
Chapter 30: Drugs Used to Treat Lower Respiratory Disease
Unit 6: Drugs Affecting the Digestive System
Chapter 31: Drugs Used to Treat Oral Disorders
Chapter 32: Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
Chapter 33: Drugs Used to Treat Nausea and Vomiting
Chapter 34: Drugs Used to Treat Constipation and Diarrhea
Unit 7: Drugs That Affect the Endocrine System
Chapter 35: Drugs Used to Treat Diabetes Mellitus
Chapter 36: Drugs Used to Treat Thyroid Disease
Chapter 37: Corticosteroids
Chapter 38: Gonadal Hormones
Unit 8: Drugs Affecting the Reproductive System
Chapter 39: Drugs Used in Obstetrics
Chapter 40: Drugs Used in Men‘s and Women‘s Health
Unit 9: Drugs Affecting Other Body Systems
Chapter 41: Drugs Used to Treat Disorders of the Urinary System
Chapter 42: Drugs Used to Treat Glaucoma and Other Eye Disorders
Chapter 43: Drugs Used to Treat Cancer
Chapter 44: Drugs Used to Treat the Musculoskeletal System
Chapter 45: Drugs Used to Treat Infection Unit 10: Drugs Affecting the General Health of the Body
Chapter 46: Nutrition
Chapter 47: Herbal and Dietary Supplemental Therapy
Chapter 48: Substance Abuse
,Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 18th Edition
MULTIPLE CHOICE
1. What is the name under which a drug is listed by the US Food and Drug
Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed by the FDA.
The brand name, or trademark, is the name given to a drug by its
manufacturer. The nonproprietary, or generic, name is provided by the
United States Adopted Names Council.
DIF: Cognitive Level: Knowledge REF: p. 2 OBJ: 1
NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
TOP:NursingProcess Step: Assessment CON: Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to nutritional
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
names, pronunciation guide, and possible future FDA approved drugs; it does not include
nutritional supplements. Natural Medicines Comprehensive Database contains evidence-based
information on herbal medicines and herbal combination products; it does not include
information specific to nutritional supplements. Drug Interaction Facts contains comprehensive
information on drug interaction facts; it does not include nutritional supplements.
DIF: Cognitive Level: Knowledge REF: p. 2 | p. 3 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment CON: Nutrition | Patient Education
3. What is the most comprehensive reference available to research a drug interaction?
a. Drug Facts and Comparisons
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
, ANS: B
First published in 1983, Drug Interaction Facts is the most comprehensive book available on
drug interactions. In addition to monographs listing various aspects of drug interactions, this
information is reviewed and updated by an internationally renowned group of physicians and
pharmacists with clinical and scientific expertise.
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which section
of the Physicians’ Desk Reference (PDR) is most helpful to get information about this drug?
a. Manufacturer‘s section
b. Brand and Generic name section
c. Product category section
d. Product information section
ANS: B
A physician‘s order would include the brand and/or generic name of the drug. The alphabetic
index in the PDR would make this section the most user-friendly. Based on a physician‘s order,
manufacturer‘s information and classification information would not be known. The
Manufacturer‘s section is a roster of manufacturers. The product category section lists products
subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and antibiotics. The
product information section contains reprints of the package inserts for the major products of
manufacturers.
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public a standard,
comprehensive, up-to-date look up and downloadable resource about medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Physicians’ Desk Reference (PDR)
ANS: C
DailyMed makes available to healthcare providers and the public a standard, comprehensive, up-
to-date look up and downloadable resource about medicines. The American Drug Index is not
appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
The PDR is not appropriate for patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 5 OBJ: 4
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
, a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
of all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
safely without medical supervision and restricts their sale to prescription by a licensed
practitioner. The Controlled Substances Act addresses only controlled substances and their
categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 OBJ: 6
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
dependency. Under which classification does this drug fall?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead
to low to moderate physical dependence or high psychological dependence. Schedule IV drugs
have low potential for abuse. Use may lead to limited physical or psychological dependence.
DIF: Cognitive Level: Comprehension REF: p. 5 OBJ: 2
NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
TOP:NursingProcess Step: Assessment CON: Patient Education | Addiction | Pain
8. What would the FDA do to expedite drug development and approval for an outbreak of
smallpox, for which there is no known treatment?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
Bruce D. Clayton Chapter 1-48
TABLE OF CONTENTS.
Unit 1: Applying Pharmacology to Nursing Practice
Chapter 1: Drug Definitions, Standards, and Information Sources
Chapter 2: Basic Principles of Drug Action and Drug Interactions
Chapter 3: Drug Action Across the Life Span
Chapter 4: The Nursing Process and Pharmacology
Chapter 5: Patient Education to Promote Health
Unit 2: Illustrated Atlas of Medication Administration
Chapter 6: Principles of Medication Administration and Medication Safety
Chapter 7: Percutaneous Administration
Chapter 8: Enteral Administration
Chapter 9: Parenteral Administration: Safe Preparation of Parenteral Medications
Chapter 10: Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular
Routes
Chapter 11: Parenteral Administration: Intravenous Route
Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems
Chapter 12: Drugs Affecting the Autonomic Nervous System
Chapter 13: Drugs Used for Sleep
Chapter 14: Drugs Used for Neurodegenerative Disorders (NEW!)
Chapter 15: Drugs Used for Anxiety Disorders
Chapter 16: Drugs Used for Depressive and Bipolar Disorders
Chapter 17: Drugs Used for Psychoses
Chapter 18: Drugs Used for Seizure Disorders
Chapter 19: Drugs Used for Pain Management
Unit 4: Drugs Affecting the Cardiovascular System
Chapter 20: Introduction to Cardiovascular Disease and Metabolic Syndrome
Chapter 21: Drugs Used to Treat Dyslipidemias
Chapter 22: Drugs Used to Treat Hypertension
Chapter 23: Drugs Used to Treat Dysrhythmias
Chapter 24: Drugs Used to Treat Angina Pectoris
Chapter 25: Drugs Used to Treat Peripheral Vascular Disease
Chapter 26: Drugs Used to Treat Thromboembolic Disorders
Chapter 27: Drugs Used to Treat Heart Failure
Chapter 28: Drugs Used for Diuresis
Unit 5: Drugs Affecting the Respiratory System
Chapter 29: Drugs Used to Treat Upper Respiratory Disease
Chapter 30: Drugs Used to Treat Lower Respiratory Disease
Unit 6: Drugs Affecting the Digestive System
Chapter 31: Drugs Used to Treat Oral Disorders
Chapter 32: Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
Chapter 33: Drugs Used to Treat Nausea and Vomiting
Chapter 34: Drugs Used to Treat Constipation and Diarrhea
Unit 7: Drugs That Affect the Endocrine System
Chapter 35: Drugs Used to Treat Diabetes Mellitus
Chapter 36: Drugs Used to Treat Thyroid Disease
Chapter 37: Corticosteroids
Chapter 38: Gonadal Hormones
Unit 8: Drugs Affecting the Reproductive System
Chapter 39: Drugs Used in Obstetrics
Chapter 40: Drugs Used in Men‘s and Women‘s Health
Unit 9: Drugs Affecting Other Body Systems
Chapter 41: Drugs Used to Treat Disorders of the Urinary System
Chapter 42: Drugs Used to Treat Glaucoma and Other Eye Disorders
Chapter 43: Drugs Used to Treat Cancer
Chapter 44: Drugs Used to Treat the Musculoskeletal System
Chapter 45: Drugs Used to Treat Infection Unit 10: Drugs Affecting the General Health of the Body
Chapter 46: Nutrition
Chapter 47: Herbal and Dietary Supplemental Therapy
Chapter 48: Substance Abuse
,Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 18th Edition
MULTIPLE CHOICE
1. What is the name under which a drug is listed by the US Food and Drug
Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed by the FDA.
The brand name, or trademark, is the name given to a drug by its
manufacturer. The nonproprietary, or generic, name is provided by the
United States Adopted Names Council.
DIF: Cognitive Level: Knowledge REF: p. 2 OBJ: 1
NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
TOP:NursingProcess Step: Assessment CON: Patient Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS: C
United States Pharmacopoeia/National Formulary contains information specific to nutritional
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
names, pronunciation guide, and possible future FDA approved drugs; it does not include
nutritional supplements. Natural Medicines Comprehensive Database contains evidence-based
information on herbal medicines and herbal combination products; it does not include
information specific to nutritional supplements. Drug Interaction Facts contains comprehensive
information on drug interaction facts; it does not include nutritional supplements.
DIF: Cognitive Level: Knowledge REF: p. 2 | p. 3 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment CON: Nutrition | Patient Education
3. What is the most comprehensive reference available to research a drug interaction?
a. Drug Facts and Comparisons
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
, ANS: B
First published in 1983, Drug Interaction Facts is the most comprehensive book available on
drug interactions. In addition to monographs listing various aspects of drug interactions, this
information is reviewed and updated by an internationally renowned group of physicians and
pharmacists with clinical and scientific expertise.
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment CON: Safety | Patient Education | Clinical Judgment
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which section
of the Physicians’ Desk Reference (PDR) is most helpful to get information about this drug?
a. Manufacturer‘s section
b. Brand and Generic name section
c. Product category section
d. Product information section
ANS: B
A physician‘s order would include the brand and/or generic name of the drug. The alphabetic
index in the PDR would make this section the most user-friendly. Based on a physician‘s order,
manufacturer‘s information and classification information would not be known. The
Manufacturer‘s section is a roster of manufacturers. The product category section lists products
subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and antibiotics. The
product information section contains reprints of the package inserts for the major products of
manufacturers.
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public a standard,
comprehensive, up-to-date look up and downloadable resource about medicines?
a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Physicians’ Desk Reference (PDR)
ANS: C
DailyMed makes available to healthcare providers and the public a standard, comprehensive, up-
to-date look up and downloadable resource about medicines. The American Drug Index is not
appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
The PDR is not appropriate for patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 5 OBJ: 4
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
, a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS: A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
of all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
safely without medical supervision and restricts their sale to prescription by a licensed
practitioner. The Controlled Substances Act addresses only controlled substances and their
categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 OBJ: 6
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
dependency. Under which classification does this drug fall?
a. I
b. II
c. III
d. IV
ANS: B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead
to low to moderate physical dependence or high psychological dependence. Schedule IV drugs
have low potential for abuse. Use may lead to limited physical or psychological dependence.
DIF: Cognitive Level: Comprehension REF: p. 5 OBJ: 2
NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
TOP:NursingProcess Step: Assessment CON: Patient Education | Addiction | Pain
8. What would the FDA do to expedite drug development and approval for an outbreak of
smallpox, for which there is no known treatment?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS: D
