Pharmacology- Final Exam Questions & Answers!

What is required for a generic substitution? - ANSWER The doctor's permission Where can official information about drugs be found? - ANSWER USPNF Which classes of drugs can be aerosolized? - ANSWER -Adrenergic -Anticholinergic -Mucoactive -Corticosteroids -Antiasthmatic -Antiinfectives -Surfactants Phases of IND approval - ANSWER -ANIMAL studies -Small #, HEALTHY subjects -Small #, subjects with the DISEASE -Large, MULTICENTER studies Drug abbreviations- Q4 vs QID - ANSWER -Q4= Every 4 hours -QID= 4 times a day *Q4 gets MORE* Portal of entry means the same as..... - ANSWER Route of administration What conditions are included in parenteral? - ANSWER -Intravenous (IV) -Intramuscular (IM) -Subcutaneous (SC) -Intrathecal (IT) -Intraosseous (IO) Factors in drug absorption - ANSWER -Bioavailability -Blood flow to the site Organ responsible for drug metabolism - ANSWER Liver Organ responsible for drug excretion - ANSWER Kidney What % of aerosol reaches the lower respiratory tract with CURRENT devices? - ANSWER 10-30%