INTRO/REVIEW
>
- MELOSIS a core of the matter !
is
subject
cells
expressed in
GENES ~ (RNA) SPEC . PROTEIN
In fo
copied
↓
~
FUNCT . ORG .
PHENOTYPE
PROGENY (normal/wild)
↓
FUNCT . ORGO .
(pheno similar to
parents
KEY GENETIC PRINCIPLES A
D MUTAGENESIS Mutations DNA-loss of
change
: in or
function
gene
:
change in
p
neno .
> COMPLEMENTATION :
adding a normal
gene
to an
organism
normal
that
has a mutated one restore function and
can a
pheno.
SEGREGATION :
melosis determines how nuclear dis-
genes
> are
tributed from
parents to
progeny during sexual reproduction
LINKAGE : close
together chromosome often Inherited
genes
- on a
together
GENETIC GLOSSARY
Inheritance
-
-gene/allele
- dominance
- mutation
X
recombo/crossing -
over
-
transcription/translation
variation
phenotype
> in
- DNA & RNA
>
- chromosomes
- melosis
> mitosis
replication
>
-
-genetic mapping distance
phylogenetics
-
-genotype/phenotype
, LECTURE LB : REVIEW
>
- a GENOME of a cell is ALL the DNA in a cell
23
haploid gamete 22 autosomes
-
genes in ;
eukaryotic nuclear
genomes are
composed of linear chromosome
-
REPLICATED consist of "sister"
joined
> chromosomes 1 chromosomes
of the contromeric considered a SINGLE Chrome. until
region
anaphase (separation
D a GENOMPE is a combination of variation in DNA sequence for
I or more
genes and/or intergenic regions of an individual
* Internal &
external .
environ
affect expression
of
genotype
-
splicing poly-A,
tail 5',
capping
*
transcriptional
FUNCTION termination not
as
specific as
translation
termination