Pharmacology RN TEST BANK REAL
EXAM 98 QUESTIONS AND CORRECT
ANSWERS WITH RATIONALES|PN
FUNDAMENTALS ATI PROCTORED
EXAM 2024. QUESTIONS & CORRECT
ANSWERS. GRADE A+
5 half-lives - ANSmost drugs are removed from the body after
Additive effects - ANSDrug interactions in which the effect of a combination of two or
more drugs with similar actions is equivalent to the sum of the individual effects of the
same drugs given alone.
Adverse drug event - ANSany undesirable occurrence related to administering or failing
to administer a prescribed medication
Adverse drug reaction - ANSany unexpected, unintended, undesired, or excessive
response to a medication given at therapeutic dosages (as opposed to overdose)
Adverse effects - ANSA general term for any undesirable effects that are a direct
response to one or more drugs.
affinity - ANSthe degree which a drug attaches to and binds with a receptor "best fit"
Agonist - ANSdrug binds to the receptor; there is a response
Allergic reaction - ANSAn immunologic hypersensitivity reaction resulting from the
unusual sensitivity of a patient to a particular medication; a type of adverse drug event.
Antagonist - ANSdrug binds to the receptor, there is no response
drug prevents binding of agonists
Antagonistic effects - ANSDrug interactions in which the effect of a combination of two
or more drugs is less than the sum of the individual effects of the same drugs given. It is
usually caused by an antagonizing (blocking or reducing) effect of one drug on another.
Bioavailability - ANSA measure of the extent of drug absorption for a given drug and
route (from 0% to 100%).
, Biotransformation - ANSOne or more biochemical reactions involving a parent drug;
occurs mainly in the liver and produces a metabolite that is either inactive or active. Also
known as metabolism.
blood-brain barrier - ANSThe barrier system that restricts the passage of various
chemicals and microscopic entities (e.g., bacteria, viruses) between the bloodstream
and the central nervous system. It still allows for the passage of essential substances
such as oxygen.
Chemical name - ANSThe name that describes the chemical composition and molecular
structure of a drug.
competitive antagonist - ANSdrug competes with the agonist for binding to the receptor.
If it binds, there is no response
compliance - ANSImplementation or fulfillment of a prescriber's or caregiver's
prescribed course of treatment or therapeutic plan by a patient.
Contraindication - ANSAny condition, especially one related to a disease state or patient
characteristic, including current or recent drug therapy, which renders a particular form
of treatment improper or undesirable.
Cytochrome P450 - ANS-The general name for a large class of enzymes that play a
significant role in drug metabolism and drug interactions.
-mainly target lipid-soluable drugs
Dependence - ANSA state in which there is a compulsive or chronic need, as for a drug
Dissolution - ANSThe process by which solid forms of drugs disintegrate in the
gastrointestinal tract and become soluble before being absorbed into the circulation.
Drug - ANSany chemical that affects the physiologic processes of a living organism
Drug actions - ANSThe processes involved in the interaction between a drug and body
cells (e.g., the action of a drug on a receptor protein); also called mechanism of action.
Drug classification - ANSA method of grouping drugs; may be based on structure or
therapeutic use.
drug classifications - ANSstructure
therapeutic
Drug effects - ANSThe physiologic reactions of the body to a drug. They can be
therapeutic or toxic and describe how the body is affected as a whole by the drug.
EXAM 98 QUESTIONS AND CORRECT
ANSWERS WITH RATIONALES|PN
FUNDAMENTALS ATI PROCTORED
EXAM 2024. QUESTIONS & CORRECT
ANSWERS. GRADE A+
5 half-lives - ANSmost drugs are removed from the body after
Additive effects - ANSDrug interactions in which the effect of a combination of two or
more drugs with similar actions is equivalent to the sum of the individual effects of the
same drugs given alone.
Adverse drug event - ANSany undesirable occurrence related to administering or failing
to administer a prescribed medication
Adverse drug reaction - ANSany unexpected, unintended, undesired, or excessive
response to a medication given at therapeutic dosages (as opposed to overdose)
Adverse effects - ANSA general term for any undesirable effects that are a direct
response to one or more drugs.
affinity - ANSthe degree which a drug attaches to and binds with a receptor "best fit"
Agonist - ANSdrug binds to the receptor; there is a response
Allergic reaction - ANSAn immunologic hypersensitivity reaction resulting from the
unusual sensitivity of a patient to a particular medication; a type of adverse drug event.
Antagonist - ANSdrug binds to the receptor, there is no response
drug prevents binding of agonists
Antagonistic effects - ANSDrug interactions in which the effect of a combination of two
or more drugs is less than the sum of the individual effects of the same drugs given. It is
usually caused by an antagonizing (blocking or reducing) effect of one drug on another.
Bioavailability - ANSA measure of the extent of drug absorption for a given drug and
route (from 0% to 100%).
, Biotransformation - ANSOne or more biochemical reactions involving a parent drug;
occurs mainly in the liver and produces a metabolite that is either inactive or active. Also
known as metabolism.
blood-brain barrier - ANSThe barrier system that restricts the passage of various
chemicals and microscopic entities (e.g., bacteria, viruses) between the bloodstream
and the central nervous system. It still allows for the passage of essential substances
such as oxygen.
Chemical name - ANSThe name that describes the chemical composition and molecular
structure of a drug.
competitive antagonist - ANSdrug competes with the agonist for binding to the receptor.
If it binds, there is no response
compliance - ANSImplementation or fulfillment of a prescriber's or caregiver's
prescribed course of treatment or therapeutic plan by a patient.
Contraindication - ANSAny condition, especially one related to a disease state or patient
characteristic, including current or recent drug therapy, which renders a particular form
of treatment improper or undesirable.
Cytochrome P450 - ANS-The general name for a large class of enzymes that play a
significant role in drug metabolism and drug interactions.
-mainly target lipid-soluable drugs
Dependence - ANSA state in which there is a compulsive or chronic need, as for a drug
Dissolution - ANSThe process by which solid forms of drugs disintegrate in the
gastrointestinal tract and become soluble before being absorbed into the circulation.
Drug - ANSany chemical that affects the physiologic processes of a living organism
Drug actions - ANSThe processes involved in the interaction between a drug and body
cells (e.g., the action of a drug on a receptor protein); also called mechanism of action.
Drug classification - ANSA method of grouping drugs; may be based on structure or
therapeutic use.
drug classifications - ANSstructure
therapeutic
Drug effects - ANSThe physiologic reactions of the body to a drug. They can be
therapeutic or toxic and describe how the body is affected as a whole by the drug.
