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Summary TOXIC EFFECTS AS A RESULT OF HERBAL MEDICINE INTAKE .

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Herbal medicines are advertised to be free from side effects, which is a myth. A large number of people still rely on herbal medicines, and some people take herbal medicines along with routine allopathic medicines especially in cases of diabetes, hypertension, thyroid disease, etc., where the patient is on long-term or lifelong treatment. Many commercial websites are available on Internet, which insist that herbal medicines have no side effects. In underdeveloped and developing countries, there are no specific laws for herbal practitioners and companies marketing herbal products. People are attracted by such companies and start using herbal medicines pertaining to be free from side effects. In this chapter, we will discuss about possible toxicities of some herbal medicines and their remedies. 2 . Possible reasons for toxic effects of herbal medicines 2.1 . Self-treatment Herbal medicines are easily available in market and can be purchased without prescription. These products are advertised on media as a miracle treatment without any side effects to attract people that are fed up with side effects or lost hope for being cured. The patients who like to play safe game are attracted in a manner that they are allowed to continue their regular medicines along with herbal treatment. Even persons caring about their health start herbal treatment to remain healthy proving the proverb “Prevention is better than cure.” As a result, a large number of people are attracted towards herbal medicines and they start self-treatment [1]. 2.2 . Unqualified practitioners In a large part of the world, unqualified practitioners are prescribing alternative therapies to patients of various diseases, apart from some countries where laws and regulations for herbal practitioners exist and implemented. Medical practitioners are provided vast knowledge about human body, drugs, mechanism of action, pharmacology, case studies, and then allowed to practice. Nowadays, Alternative Medicine Degree Course is available in certain universities with highly qualified and experienced faculty, which is a good source of herbal practitioners, but still 50% of herbal practitioners in the world are unqualified who acquire this profession after their forefathers such as a son of a farmer becomes a farmer, or after reading some books about herbal medicine, conducting 6-month online course about herbal medicine, etc., and start practicing. In underdeveloped countries, people are attracted towards these quacks due to economic reasons and start taking herbal medicine. These unqualified practitioners themselves are not aware of toxic effects of herbal medicines, and if the patient complains, they cannot rectify their mistake. 2.3 . Sub-standard product There are many sub-standard herbal products available in the market. The reason is that these products are not tested accordingly for quality before marketing. Some contain less amount of active ingredient and some do not contain active ingredient at all as a result of incorrect identification of plant by the collector, using adulterant instead of original plant or due to improper storage of plant material, and it loses its efficacy. Sometimes the herbal products contain material not defined on label such as non-herb material, minerals, heavy metals, and addition of particular pharmaceutical product. Occasionally they may contain toxins and pesticides, which is much more dangerous and one of the major reasons of toxic effects after herbal medicine intake [2].

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TOXIC EFFECTS AS A
RESULT OF HERBAL
MEDICINE INTAKE

,Abstract

Concurrent use of herbs with therapeutic drugs increases the potential of herb-drug
interactions. The clinical importance of herb-drug interactions is associated with the
particular herb, drug, and patient profile. Herbs are potentially potent as they affect
body functions. The use herbal medicine and supplements can be risky as they are
not subject to review by the FDA. In this chapter, we make an attempt to discuss the
possible reasons for toxic effects, types of toxicities, some reported cases of toxicities
involving the use of herbal medicine alone, and some herb-drug interactions. In
addition to this, possible ways to reduce toxic effects of herbal medicines have also
been discussed.

Keywords: herbal medicine, toxicity, reported cases, herb-drug interaction

,1 . Introduction

Herbal medicines are advertised to be free from side effects, which is a myth. A large
number of people still rely on herbal medicines, and some people take herbal medicines
along with routine allopathic medicines especially in cases of diabetes, hypertension,
thyroid disease, etc., where the patient is on long-term or lifelong treatment. Many
commercial websites are available on Internet, which insist that herbal medicines have no
side effects. In underdeveloped and developing countries, there are no specific laws for
herbal practitioners and companies marketing herbal products. People are attracted by such
companies and start using herbal medicines pertaining to be free from side effects. In this
chapter, we will discuss about possible toxicities of some herbal medicines and their
remedies.

, 2 . Possible reasons for toxic effects of herbal medicines

2.1 . Self-treatment


Herbal medicines are easily available in market and can be purchased without prescription.
These products are advertised on media as a miracle treatment without any side effects to
attract people that are fed up with side effects or lost hope for being cured. The patients who
like to play safe game are attracted in a manner that they are allowed to continue their
regular medicines along with herbal treatment. Even persons caring about their health start
herbal treatment to remain healthy proving the proverb “Prevention is better than cure.” As
a result, a large number of people are attracted towards herbal medicines and they start self-
treatment
[1].


2.2 . Unqualified practitioners


In a large
part of the

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