NoLiengatlncadal fli
deytsed to Shudy lue time couNte deug n he
boy oithaut asumlog any, corpantno medel
+basd on 8tatstical momnt heony.
> Alss
called sHAm(shape alssweigti
Nor- comparmer omalysis aNeas, moment
no) os mod
Knon
Lhdependent mehads
Compamentmode
OThese eBQire elabosate
somphiop to ft te data,
cure frtting o exper
rntal data wng conpute
a tedious
sinple algebeic equa
-NO were
éna pK
as Stai&ticadistojbutor
5 These aee Useful fof.
nst o e stuation. application of dinial p
though asurption of BA bE stli e
meslin4 OUee aolest
o Deavation of pK paMamefe u , bet of
simple a¡eb oie eauotbn&.
nathemetca tx Remauns Bame or rug
o7 7mefabolate psovide eiminatn folw)
irete wt l
follon ixt
avaraje
, Appicaton Nom-tamparfmunt modl';
OIt 8 zed to estimate mp pharmaloMintie
panamtetA iki - A, clearant vd
Or wsed in duleminjin TA sat of
absosptòn and fisst
fistt 1yptian
sotistical moenoxda
Te Tc hime couske
L: Bo momntmBan anea)
Q fiset momn (mkT- mean tees)denca timu)
Secorol monent ( VmRT - vari ance of mkr)
Ozero momnt : Refereud to total area
nden
plasma drug conc from zero to
Apl'cation calculating bA. leasaneeinfmgAvc.
* Tkap ezidal Avc calculatons
UThe aNea b/w tme interyals in the aren e tsapezoid
Can calculate
Ave]
tn
= Catn
(tn-ta
he toBal Auc blw
Te 1 g4 s is oo toinud
adinA Smallen Avc valuws
tn t3
t
tn K
yTape zoi) 7lo Galate total AUc from ttz6 to
=
+
K
MRT= ct dt
je dt.
deytsed to Shudy lue time couNte deug n he
boy oithaut asumlog any, corpantno medel
+basd on 8tatstical momnt heony.
> Alss
called sHAm(shape alssweigti
Nor- comparmer omalysis aNeas, moment
no) os mod
Knon
Lhdependent mehads
Compamentmode
OThese eBQire elabosate
somphiop to ft te data,
cure frtting o exper
rntal data wng conpute
a tedious
sinple algebeic equa
-NO were
éna pK
as Stai&ticadistojbutor
5 These aee Useful fof.
nst o e stuation. application of dinial p
though asurption of BA bE stli e
meslin4 OUee aolest
o Deavation of pK paMamefe u , bet of
simple a¡eb oie eauotbn&.
nathemetca tx Remauns Bame or rug
o7 7mefabolate psovide eiminatn folw)
irete wt l
follon ixt
avaraje
, Appicaton Nom-tamparfmunt modl';
OIt 8 zed to estimate mp pharmaloMintie
panamtetA iki - A, clearant vd
Or wsed in duleminjin TA sat of
absosptòn and fisst
fistt 1yptian
sotistical moenoxda
Te Tc hime couske
L: Bo momntmBan anea)
Q fiset momn (mkT- mean tees)denca timu)
Secorol monent ( VmRT - vari ance of mkr)
Ozero momnt : Refereud to total area
nden
plasma drug conc from zero to
Apl'cation calculating bA. leasaneeinfmgAvc.
* Tkap ezidal Avc calculatons
UThe aNea b/w tme interyals in the aren e tsapezoid
Can calculate
Ave]
tn
= Catn
(tn-ta
he toBal Auc blw
Te 1 g4 s is oo toinud
adinA Smallen Avc valuws
tn t3
t
tn K
yTape zoi) 7lo Galate total AUc from ttz6 to
=
+
K
MRT= ct dt
je dt.
