SBB HUMAN BLOOD GROUPS EXAM
(ACTUAL EXAM) WITH 159 QUESTIONS
WITH VERY ELABORATED ANSWERS
CORRECTRY WELL ORGANIZED LATEST
2024 – 2025 ALREADY GRADED A+
Which cells would be devoid of glycophorin B - ANSWERS-Mk/Mk
What is unique about the In(Jk) gene - ANSWERS-Resistance to lysis in 2M urea
This Duffy antigen is not altered by ficin or papain - ANSWERS-Fy3
A patient whose red cells type as D+C-E-c-e- Evans+ could form what antibody? -
ANSWERS-Anti-Hro
What does rh' represent in the Weiner nomenclature - ANSWERS-C
,Which of the following may produce anti-Rh29 - ANSWERS-Rh null persons
What type of RBCs would you transfuse to a patient with anti-G - ANSWERS-RBCs
transfused must lack the D and C antigens
Can you detect a weak D using Gel Technology? - ANSWERS-No, because there is
no washing phase
Can an Rh positive father and Rh positive mother yield an Rh negative child -
ANSWERS-Yes, if both parents are heterozygous for the D gene. Inheritance is
autosomal recessive
What type of RBCs in regards to Rh phenotype would you transfuse in a patient
with anti-f - ANSWERS-RBCs should be negative for the c and e antigens
How could you solve an ABO discrepancy where Anti-M was causing aberrant
results in reverse grouping when the forward type is consistent with A blood
group and reverse as O? - ANSWERS-Treat A1 cells with ficin to denature the M
antigen, repeat reverse grouping with ficin-treated A1 cells.
How would Ulex europaeus react with O, A, A2, B, A2B, A1B RBCs? - ANSWERS-
O>A2>B>A2B>A1>A1B
, How could you distinguish serologically A1, A2 and A3 - ANSWERS-Dolichos
biflorus can will react with A1 and not A2. A3 yields mixed field reactions with
anti-A and anti-A,B
What is the correct order of type of RBCs to transfuse in an AB patient when AB
RBCs are not available? Why? - ANSWERS-A, B, O; the residual anti-B in A RBCs is
less immunogenic than the residual anti-A in B RBCs
Why do you see an anti-N like specificity in dialysis patients? - ANSWERS-
Formaldehyde induced antibody to 'N' due to formaldehyde used in dialysis
procedures.
A patient types as follows: anti-A=4+, Anti-B=1+, A1 Cells=2+, B cells=4+. The ABO
discrepancy led to suspicion of a possible cold autoantibody based on patient
histopry and diagnosis. RESt was used in an attept to adsorb the autoantobidy.
The type was repeated with adsorbed plasma Anit-A=4+, Anti-B=0, A1 cells=0, B
cells=0. What could be the cause of this discrepancy? - ANSWERS-Anti-B was
adsorbed out with RESt.
What enzyme may be useful in distinguishing anti-Ge2? - ANSWERS-papain
The beta 1-3 linkage between galactose and N-acetylglucosamine is found in? -
ANSWERS-secretions
(ACTUAL EXAM) WITH 159 QUESTIONS
WITH VERY ELABORATED ANSWERS
CORRECTRY WELL ORGANIZED LATEST
2024 – 2025 ALREADY GRADED A+
Which cells would be devoid of glycophorin B - ANSWERS-Mk/Mk
What is unique about the In(Jk) gene - ANSWERS-Resistance to lysis in 2M urea
This Duffy antigen is not altered by ficin or papain - ANSWERS-Fy3
A patient whose red cells type as D+C-E-c-e- Evans+ could form what antibody? -
ANSWERS-Anti-Hro
What does rh' represent in the Weiner nomenclature - ANSWERS-C
,Which of the following may produce anti-Rh29 - ANSWERS-Rh null persons
What type of RBCs would you transfuse to a patient with anti-G - ANSWERS-RBCs
transfused must lack the D and C antigens
Can you detect a weak D using Gel Technology? - ANSWERS-No, because there is
no washing phase
Can an Rh positive father and Rh positive mother yield an Rh negative child -
ANSWERS-Yes, if both parents are heterozygous for the D gene. Inheritance is
autosomal recessive
What type of RBCs in regards to Rh phenotype would you transfuse in a patient
with anti-f - ANSWERS-RBCs should be negative for the c and e antigens
How could you solve an ABO discrepancy where Anti-M was causing aberrant
results in reverse grouping when the forward type is consistent with A blood
group and reverse as O? - ANSWERS-Treat A1 cells with ficin to denature the M
antigen, repeat reverse grouping with ficin-treated A1 cells.
How would Ulex europaeus react with O, A, A2, B, A2B, A1B RBCs? - ANSWERS-
O>A2>B>A2B>A1>A1B
, How could you distinguish serologically A1, A2 and A3 - ANSWERS-Dolichos
biflorus can will react with A1 and not A2. A3 yields mixed field reactions with
anti-A and anti-A,B
What is the correct order of type of RBCs to transfuse in an AB patient when AB
RBCs are not available? Why? - ANSWERS-A, B, O; the residual anti-B in A RBCs is
less immunogenic than the residual anti-A in B RBCs
Why do you see an anti-N like specificity in dialysis patients? - ANSWERS-
Formaldehyde induced antibody to 'N' due to formaldehyde used in dialysis
procedures.
A patient types as follows: anti-A=4+, Anti-B=1+, A1 Cells=2+, B cells=4+. The ABO
discrepancy led to suspicion of a possible cold autoantibody based on patient
histopry and diagnosis. RESt was used in an attept to adsorb the autoantobidy.
The type was repeated with adsorbed plasma Anit-A=4+, Anti-B=0, A1 cells=0, B
cells=0. What could be the cause of this discrepancy? - ANSWERS-Anti-B was
adsorbed out with RESt.
What enzyme may be useful in distinguishing anti-Ge2? - ANSWERS-papain
The beta 1-3 linkage between galactose and N-acetylglucosamine is found in? -
ANSWERS-secretions
