Test Bank For Pharmacology Clear
and Simple A Guide to Drug
Classifications and Dosage
Calculations 4th Edition By Cynthia
J. Watkins | Chapter 1 – 20-Latest-
What are some sources of drugs? - answer-Animal, plants, mineral, &
Chemical synthesis
How are drugs named? - answer-* Code name
*Chemical name *Generic name, *Trade name
How are new drugs tested on people? - answer-Phase I: small # of healthy
people
Phase II: small # of subjects w/disease
Phase III: large group in multicenter studies
Routes of drug administration? - answer-*Enteral, parenteral, transdermal,
inhalation, & topical
, When a drug taken orally is absorbed into the bloodstream from the
stomach, metabolized by the liver, and drains directly into the inferior vena
cava, it is called: - answer-First pass effect
If a drug is highly metabolized by the liver enzymes: - answer-Most of the
drug will be metabolized before reaching the systemic circulation.
What organ is primarily responsible for excrection? - answer-Kidneys
T or F: Liver or kidney disease can alter the clearance of a drug by these
organs. - answer-True
What does L/T ratio stand for? - answer-Lung availability/Total systemic
availability
The higher the L/T ratio: - answer-The better the drug delivery
Factors that increase L/T ratio of inhaled drugs: - answer-* High airway/low
GI delivery
* Rinsing and spitting after inhalation
* Using a reservoir device
Inhaled drugs with high first pass metabolism: - answer-* Albuterol 50%
* Budesonide 90%
How do most drugs exert their effects? - answer-By binding to targeted
protein.
How are enteral drugs administered? - answer-Oral, suppositories,
sublingual, & indwelling gastric tube
How are enteral drugs absorbed? - answer-Anywhere along the GI tract
How are parenteral drugs administered? - answer-Injected
In which ways can parenteral drugs be injected? - answer-* Subcutaneous
* Intramuscular
* Intravenous
* Intrathecal
* Intraosseous
and Simple A Guide to Drug
Classifications and Dosage
Calculations 4th Edition By Cynthia
J. Watkins | Chapter 1 – 20-Latest-
What are some sources of drugs? - answer-Animal, plants, mineral, &
Chemical synthesis
How are drugs named? - answer-* Code name
*Chemical name *Generic name, *Trade name
How are new drugs tested on people? - answer-Phase I: small # of healthy
people
Phase II: small # of subjects w/disease
Phase III: large group in multicenter studies
Routes of drug administration? - answer-*Enteral, parenteral, transdermal,
inhalation, & topical
, When a drug taken orally is absorbed into the bloodstream from the
stomach, metabolized by the liver, and drains directly into the inferior vena
cava, it is called: - answer-First pass effect
If a drug is highly metabolized by the liver enzymes: - answer-Most of the
drug will be metabolized before reaching the systemic circulation.
What organ is primarily responsible for excrection? - answer-Kidneys
T or F: Liver or kidney disease can alter the clearance of a drug by these
organs. - answer-True
What does L/T ratio stand for? - answer-Lung availability/Total systemic
availability
The higher the L/T ratio: - answer-The better the drug delivery
Factors that increase L/T ratio of inhaled drugs: - answer-* High airway/low
GI delivery
* Rinsing and spitting after inhalation
* Using a reservoir device
Inhaled drugs with high first pass metabolism: - answer-* Albuterol 50%
* Budesonide 90%
How do most drugs exert their effects? - answer-By binding to targeted
protein.
How are enteral drugs administered? - answer-Oral, suppositories,
sublingual, & indwelling gastric tube
How are enteral drugs absorbed? - answer-Anywhere along the GI tract
How are parenteral drugs administered? - answer-Injected
In which ways can parenteral drugs be injected? - answer-* Subcutaneous
* Intramuscular
* Intravenous
* Intrathecal
* Intraosseous
