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,BarBiturates
antidote: ________
Class: ________
use: ________
aCtion: ________
side effeCts: ________ - CorreCt ansWers
antidote:aCtivated CharCoal for overdose
Class: Cns depressant
use:
• daytime sedation
• induCtion of sleep
• suppression of seizures
• General anesthesia
aCtion: Bind to GaBa-a reCeptor, ↑Ch ion Channel
flux By ↑ Channel open time.
side effeCts:
• toleranCe/ dependenCe
• aBuse (hiGh potential)
• multiple druG interaCtions
• aCCelerates metaBolism of itself & other druGs
• respiratory failure
• death
therapeutiCs - CorreCt ansWers use of druGs to
diaGnose, prevent, or treat disease (effeCt)
,pharmaCokinetiCs - CorreCt ansWers metaBolism
& aCtion of druGs on the Body.
aBsorption, duration, distriBution, exCretion
pharmaCodynamiCs - CorreCt ansWers
moleCular interaCtions of a druG W/ BioloGiCal
reCeptors on Cells that lead to therapeutiC
responses.
side effeCt - CorreCt ansWers seCondary effeCt
produCed at therapeutiC doses that're
Bothersome, not harmful to pt
adverse effeCt - CorreCt ansWers harmful
undesiraBle effeCts.
allerGiC reaCtion - CorreCt ansWers immune
response to a druG after prior sensitization has
oCCurred.
idiosynCratiC effeCt - CorreCt ansWers
unCommon druG response resultinG from a
GenetiC predisposition.
intended effeCt - CorreCt ansWers effeCts We
Want to see that're therapeutiC When usinG the
druG.
teratoGeniC effeCt - CorreCt ansWers druG-
induCed Birth defeCt.
, paradoxiCal effeCt - CorreCt ansWers opp of the
intended effeCt.
iatroGeniC disease - CorreCt ansWers disease
oCCurs as a result of mediCal treatment,
produCed By druGs.
aGonist - CorreCt ansWers ↑reCeptor aCtivation.
meds that Bind/mimiC reCeptor aCtivity.
produCe response
antaGonist - CorreCt ansWers ↓reCeptor
aCtivation. meds that BloCk reCeptor aCtivity or
inhiBit it.
BloCk response
partial antaGonist - CorreCt ansWers aCt as
Both aGonist & antaGonist W/ limited affinity at
reCeptor sites.
half-life - CorreCt ansWers time it takes for ½ of
the druG to Be out of the system.
What orGan is the site of most druG metaBolism? -
CorreCt ansWers liver