NU641 Week 11 Questions with correct answers
Generalized seizure types (6) Correct Answer--Tonic clonic (grand mal)
-Absence (petit mal)
-Clonic
-Myoclonic
-Tonic
-Atonic
Status epilepticus (2) Correct Answer--Two or more seizures without
full consciousness between seizure episodes
-Requires immediate treatment
Absence seizures Correct Answer--Impaired consciousness for short
period of time
-Typically seen in children 4 to 12
-EEG typically shows generalized 3 Hz waves
Focal seizure types (2) Correct Answer--Simple partial
-Complex partial
Antiepileptic drugs mechanism of action (4) Correct Answer--Reducing
sodium and/or calcium influx into brain cells
-Causes increase in inhibitory gamma-amino butyric acid (GABA)
activity
, -Enhances influx of chloride
-Interferes with excitatory glutamate transmission
Antiepileptic agents that reduce efficacy of oral contraceptives (3)
Correct Answer--Phenytoin
-Phenobarbital
-Carbamazepine
Seizure medications and pregnancy Correct Answer--None are safe
-Use only if benefit outweighs risk and patient realizes potential of birth
defects
Phenytoin (Dilantin) (2) Correct Answer--Highly plasma protein bound
-Serum levels 10 to 20 mcg/ml should be interpreted according to
patient's serum albumin level
Fosphenytoin (2) Correct Answer--Prodrug that is converted to
phenytoin
-Can be given IM
Hypersensitivity syndrome and phenytoin Correct Answer--Can occur
about 3 to 8 weeks after starting therapy
Gabapentin (4) Correct Answer--GABA analog
-Does not increase GABA brain levels
Generalized seizure types (6) Correct Answer--Tonic clonic (grand mal)
-Absence (petit mal)
-Clonic
-Myoclonic
-Tonic
-Atonic
Status epilepticus (2) Correct Answer--Two or more seizures without
full consciousness between seizure episodes
-Requires immediate treatment
Absence seizures Correct Answer--Impaired consciousness for short
period of time
-Typically seen in children 4 to 12
-EEG typically shows generalized 3 Hz waves
Focal seizure types (2) Correct Answer--Simple partial
-Complex partial
Antiepileptic drugs mechanism of action (4) Correct Answer--Reducing
sodium and/or calcium influx into brain cells
-Causes increase in inhibitory gamma-amino butyric acid (GABA)
activity
, -Enhances influx of chloride
-Interferes with excitatory glutamate transmission
Antiepileptic agents that reduce efficacy of oral contraceptives (3)
Correct Answer--Phenytoin
-Phenobarbital
-Carbamazepine
Seizure medications and pregnancy Correct Answer--None are safe
-Use only if benefit outweighs risk and patient realizes potential of birth
defects
Phenytoin (Dilantin) (2) Correct Answer--Highly plasma protein bound
-Serum levels 10 to 20 mcg/ml should be interpreted according to
patient's serum albumin level
Fosphenytoin (2) Correct Answer--Prodrug that is converted to
phenytoin
-Can be given IM
Hypersensitivity syndrome and phenytoin Correct Answer--Can occur
about 3 to 8 weeks after starting therapy
Gabapentin (4) Correct Answer--GABA analog
-Does not increase GABA brain levels
