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genetic disorders risk factors:
-maternal age >35
-family hx
-hx of previous child w/ genetic disorder/genetic abnormality
teratogens
-drugs, viruses, infection, or exposures that cause embryonic abnormalities
-vulnerable during 1st 8 wks
-fetal growth restriction or organ size reduction after 13wks
teratogenic agents: drugs/alcohol
-alcohol
-ace inhibitors
-anticonvulsants
-cocaine
-warfarin
teratogenic agents: infections/viruses
-cytomegalovirus
-chicken pocs
-rubella
-syphilis
fetal development: 12 weeks
-heart tones can be heard by doppler
-external genitalia are developed
fetal development: 16 weeks
-teeth form
-meconium formed in intestines
fetal development: 20 weeks
-lanugo & vernix cover body
-brown fat develops
fetal development: 24 weeks
-lungs produce surfactant
-respiratory movements detected
fetal development: 28 weeks
-gas exchange possible
-eyelids open
fetal development: 32 weeks
bones fully develop
fetal development: 36 weeks
-lanugo disappears
-labias both prominent
, fetal development: 40 weeks
-all organs fully developed
full pregnancy term
38-40 weeks
placenta function
-supply oxygen
-remove wastes
-Immune protection
- supply progesterone, estrogen and hCG
what can cross placenta membrane?
- Viruses (rubella & cytomegalovirus)
- Drugs (do not give to category c, d, x)
genetic testing: prenatal
-early detection of genetic disorders
genetic testing: newborn
-detects genetic disorders in life
amniotic fluid
-fluid within the amniotic sac that surrounds and protects the fetus
-constant thermal environment
amniotic fluid: 1st trimester
contained in amniotic sac/membrane
amniotic fluid: 2nd & 3rd trimester
produced by fetal kidneys
polyhydramnios
excessive amniotic fluid
-1500 to 2000mL
oligohydramnios
too little amniotic fluid
-<500 mL or 50% reduction of normal fluid amount
-related to decrease in placental function
newborns of mothers with polyhydramnios have increased incidence of:
chromosomal, gastric, cardiac, and neural tube disorders
newborns of mothers with oligohydramnios have increased incidence of:
congenital renal problems
umbilical cord function:
-to act like a barrier between the fetus and the placenta
-contains blood vessels that link the fetus and the mother to transfer things like nutrients
and drugs
-keeps diseases out
umbilical cord: AVA
A- artery: deoxygenated blood
V- vein: oxygenated blood
A- deoxygenated blood
infertility is defined as:
the inability to conceive or remain pregnant after trying for 12 months
infertility in women >35 is: