1. Angina of effort:-
(a). Acute attack → S/L
(b). Immediate prophylaxis
(c). Long term prophylaxis (Maintainance)
Oral
Transdermal
Skin ointment
2. Variant Angina
,Clinical indications cont’d
3. Unstable angina:-
I/v infusion:
↓O2 demand
Dil of Epicard. C.V
↓Platelet Aggr.
4. Acute C.C.F
5. M.I (LVF. Associated with MI → I/v inf of NG limits
infarct size)
6. Cyanide poisoning → Antidote
7. Can be used for relaxing effect on biliary smooth
muscle.
, 8. Interventional cardiac procedures :
Percutaneous coronary angioplasty
Thrombolytic therapy of MI
9. Oesophageal spasm & Achalasia .
10. Recreational use Amyl Nitrite & Isobutyl
Nitrtite
(a). Acute attack → S/L
(b). Immediate prophylaxis
(c). Long term prophylaxis (Maintainance)
Oral
Transdermal
Skin ointment
2. Variant Angina
,Clinical indications cont’d
3. Unstable angina:-
I/v infusion:
↓O2 demand
Dil of Epicard. C.V
↓Platelet Aggr.
4. Acute C.C.F
5. M.I (LVF. Associated with MI → I/v inf of NG limits
infarct size)
6. Cyanide poisoning → Antidote
7. Can be used for relaxing effect on biliary smooth
muscle.
, 8. Interventional cardiac procedures :
Percutaneous coronary angioplasty
Thrombolytic therapy of MI
9. Oesophageal spasm & Achalasia .
10. Recreational use Amyl Nitrite & Isobutyl
Nitrtite
