Understanding Pathophysiology 7th Edition Test Bank
f f f f f
Chapterf1.fCellularfBiology
MULTIPLEfCHOICE
1. Afstudentfisfobservingfafcellfunderfthefmicroscope.fItfisfobservedftofhavefsupercoiledfDNAfwit
hfhistones.fWhichfofftheffollowingfwouldfalsofbefobservedfbyfthefstudent?
a. Afsinglefcircularfchromosome
b. Afnucleus
c. Free-floatingfnuclearfmaterial
d. Noforganelles
ANS:fB
Thefcellfdescribedfisfafeukaryoticfcell,fsofitfhasfhistonesfandfafsupercoiledfDNAfwithinfitsfnucl
eus;fthus,fthefnucleusfshouldfbefobserved.
Afsinglefcircularfchromosomefisfcharacteristicfoffprokaryoticfcells,fwhichfdofnotfhavefhistones.
Free-
floatingfnuclearfmaterialfdescribesfafprokaryoticfcell,fwhichfwouldfnotfhavefafdistinctfnucleus.
Eukaryoticfcellsfhavefmembranefboundedfcellularfcomponentsfcalledforganelles.fNoforganellesfde
scribesfafprokaryoticfcell.
2. Afnursefisfinstructingfthefstafffaboutfcellularffunctions.fWhichfcellularffunctionfisfthefnursefdes
cribingfwhenfanfisolatedfcellfabsorbsfoxygenfandfusesfitftoftransformfnutrientsftofenergy?
a. Metabolicfabsorption
b. Communication
c. Secretion
d. Respiration
,ANS:fD
Thefabilityfoffthefcellftofabsorbfoxygenfrefersftofthefcellsffunctionfoffrespiration.
Thefabilityfoffthefcellftoffunctionfwithinfafsocietyfoffcellsfrefersftofitsffunctionfoffcom
munication.
Thefabilityfoffthefcellftoftakefinfnutrientsfrefersftofthefcellsffunctionfoffmetabolicfabsorption.
Thefabilityfoffthefcellftofsynthesizefnewfsubstancesfandfsecretefthesefelsewherefrefersftofthefcellsffun
ctionfoffsecretion.
3. AfeukaryoticfcellfisfundergoingfDNAfreplication.fInfwhichfregionfoffthefcellfwouldfmostfoffthef
geneticfinformationfbefcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS:fC
Thefregionfoffthefcellfthatfcontainsfgeneticfmaterial,fincludingfaflargefamountfoffribonucleicfaci
d,fmostfoffthefDNA,fandfDNA-bindingfproteins,fisfthefnucleolus.
Thefmitochondriafisfthefsitefoffcellularfrespiration.
Thefribosomesfarefinvolvedfinfmanufacturingfoffproteinsfwithinfthefcell.
Thefnucleusfcontainsfthefnucleolus,fandfitfisfthefnucleolusfthatfcontainsfgeneticfmaterial.
4. Theffluidfmosaicfmodelfforfbiologicfmembranesfdescribesfmembranefbehavior.fAccordingftofthi
sfmodel,fwhichfofftheffollowingffloatfsinglyforfasfaggregatesfinftheffluidflipidfbilayer?
a. Peripheralfmembranefproteins
b. Integralfmembranefproteins
,c. Glycoproteins
d. Cellfadhesionfmolecules
ANS:fB
Integralfmembranefproteinsffloatffreelyfinftheffluidflipidfbilayer.
Peripheralfmembranefproteinsfarefnotfembeddedfinftheflayer,fbutfresidefatfthefsurface.fGl
ycoproteinsfactfasfcellfsurfacefmarkers.
Cellfadhesionfmoleculesfarefonfthefoutsidefoffthefmembranefandfallowfcellsftofhookftogether.
5. Whichfofftheffollowingfcanfbindftofplasmafmembranefreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicflipids
d. Ligands
ANS:fD
Ligandsfarefspecificfmoleculesfthatfcanfbindfwithfreceptorsfonfthefcellfmembrane.fOxyge
nfmovesfbyfdiffusion;fitfdoesfnotfbindftofreceptors.
Ribosomesfmakefproteinsfandfarefnotfinvolvedfinfbinding.fA
mphipathicflipidsfarefafportionfoffthefcellfmembrane.
6. Afnursefisfreviewingfafreportffromfafpatientfwithfmetastaticfcancer.fWhatffindingfwouldfsup
portfthefdiagnosisfoffmetastaticfcancer?fAlterationsfinfextracellularfmatrixfthatfinclude:
a. Decreasedffibronectin
b. Increasedfcollagen
c. Decreasedfelastin
, d. Increasedfglycoproteins
ANS:fA
Reducedfamountsfofffibronectinfareffoundfinfsomeftypesfoffcancerousfcells,fallowingfcancerfcel
lsftoftravel,forfmetastasize.
Collagenfprovidesfstrength,fandfitsfbreakdownfisfassociatedfwithfosteoarthritis,fnotfcancer.
Elastinfisffoundfinftheflungsfandfallowsftissuesftofstretch;fitfisfnotfassociatedfwithfcancerousfcells.
Decreased,fnotfincreased,fglycoproteinsfarefassociatedfwithfcancerousfcells.
7. Whichfformfoffcellfcommunicationfisfusedftofrelateftofotherfcellsfinfdirectfphysicalfcontact?
a. Cellfjunction
b. Gapfjunction
c. Desmosomes
d. Tightfjunctions
ANS:fA
Cellfjunctionsfholdfcellsftogetherfandfpermitfmoleculesftofpassffromfcellftofcell.
Gapfjunctionsfallowfcommunicationffromfthefinsidefoffonefcellftofthefinsidefoffanother.fDe
smosomesfarefnotfinvolvedfinfcommunication,fbutfallowfcellsftofholdftogether.
Tightfjunctionsfarefbarriersfthatfpreventfmovementfoffsomefsubstancesfandfleakagesfoffothers.
8. Pancreaticfbetafcellsfsecretefinsulin,fwhichfinhibitsfsecretionfoffglucagonffromfneighboringfal
phafcells.fThisfactionfisfanfexamplefoffwhichfofftheffollowingfsignalingftypes?
a. Paracrine
b. Autocrine
f f f f f
Chapterf1.fCellularfBiology
MULTIPLEfCHOICE
1. Afstudentfisfobservingfafcellfunderfthefmicroscope.fItfisfobservedftofhavefsupercoiledfDNAfwit
hfhistones.fWhichfofftheffollowingfwouldfalsofbefobservedfbyfthefstudent?
a. Afsinglefcircularfchromosome
b. Afnucleus
c. Free-floatingfnuclearfmaterial
d. Noforganelles
ANS:fB
Thefcellfdescribedfisfafeukaryoticfcell,fsofitfhasfhistonesfandfafsupercoiledfDNAfwithinfitsfnucl
eus;fthus,fthefnucleusfshouldfbefobserved.
Afsinglefcircularfchromosomefisfcharacteristicfoffprokaryoticfcells,fwhichfdofnotfhavefhistones.
Free-
floatingfnuclearfmaterialfdescribesfafprokaryoticfcell,fwhichfwouldfnotfhavefafdistinctfnucleus.
Eukaryoticfcellsfhavefmembranefboundedfcellularfcomponentsfcalledforganelles.fNoforganellesfde
scribesfafprokaryoticfcell.
2. Afnursefisfinstructingfthefstafffaboutfcellularffunctions.fWhichfcellularffunctionfisfthefnursefdes
cribingfwhenfanfisolatedfcellfabsorbsfoxygenfandfusesfitftoftransformfnutrientsftofenergy?
a. Metabolicfabsorption
b. Communication
c. Secretion
d. Respiration
,ANS:fD
Thefabilityfoffthefcellftofabsorbfoxygenfrefersftofthefcellsffunctionfoffrespiration.
Thefabilityfoffthefcellftoffunctionfwithinfafsocietyfoffcellsfrefersftofitsffunctionfoffcom
munication.
Thefabilityfoffthefcellftoftakefinfnutrientsfrefersftofthefcellsffunctionfoffmetabolicfabsorption.
Thefabilityfoffthefcellftofsynthesizefnewfsubstancesfandfsecretefthesefelsewherefrefersftofthefcellsffun
ctionfoffsecretion.
3. AfeukaryoticfcellfisfundergoingfDNAfreplication.fInfwhichfregionfoffthefcellfwouldfmostfoffthef
geneticfinformationfbefcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus
ANS:fC
Thefregionfoffthefcellfthatfcontainsfgeneticfmaterial,fincludingfaflargefamountfoffribonucleicfaci
d,fmostfoffthefDNA,fandfDNA-bindingfproteins,fisfthefnucleolus.
Thefmitochondriafisfthefsitefoffcellularfrespiration.
Thefribosomesfarefinvolvedfinfmanufacturingfoffproteinsfwithinfthefcell.
Thefnucleusfcontainsfthefnucleolus,fandfitfisfthefnucleolusfthatfcontainsfgeneticfmaterial.
4. Theffluidfmosaicfmodelfforfbiologicfmembranesfdescribesfmembranefbehavior.fAccordingftofthi
sfmodel,fwhichfofftheffollowingffloatfsinglyforfasfaggregatesfinftheffluidflipidfbilayer?
a. Peripheralfmembranefproteins
b. Integralfmembranefproteins
,c. Glycoproteins
d. Cellfadhesionfmolecules
ANS:fB
Integralfmembranefproteinsffloatffreelyfinftheffluidflipidfbilayer.
Peripheralfmembranefproteinsfarefnotfembeddedfinftheflayer,fbutfresidefatfthefsurface.fGl
ycoproteinsfactfasfcellfsurfacefmarkers.
Cellfadhesionfmoleculesfarefonfthefoutsidefoffthefmembranefandfallowfcellsftofhookftogether.
5. Whichfofftheffollowingfcanfbindftofplasmafmembranefreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicflipids
d. Ligands
ANS:fD
Ligandsfarefspecificfmoleculesfthatfcanfbindfwithfreceptorsfonfthefcellfmembrane.fOxyge
nfmovesfbyfdiffusion;fitfdoesfnotfbindftofreceptors.
Ribosomesfmakefproteinsfandfarefnotfinvolvedfinfbinding.fA
mphipathicflipidsfarefafportionfoffthefcellfmembrane.
6. Afnursefisfreviewingfafreportffromfafpatientfwithfmetastaticfcancer.fWhatffindingfwouldfsup
portfthefdiagnosisfoffmetastaticfcancer?fAlterationsfinfextracellularfmatrixfthatfinclude:
a. Decreasedffibronectin
b. Increasedfcollagen
c. Decreasedfelastin
, d. Increasedfglycoproteins
ANS:fA
Reducedfamountsfofffibronectinfareffoundfinfsomeftypesfoffcancerousfcells,fallowingfcancerfcel
lsftoftravel,forfmetastasize.
Collagenfprovidesfstrength,fandfitsfbreakdownfisfassociatedfwithfosteoarthritis,fnotfcancer.
Elastinfisffoundfinftheflungsfandfallowsftissuesftofstretch;fitfisfnotfassociatedfwithfcancerousfcells.
Decreased,fnotfincreased,fglycoproteinsfarefassociatedfwithfcancerousfcells.
7. Whichfformfoffcellfcommunicationfisfusedftofrelateftofotherfcellsfinfdirectfphysicalfcontact?
a. Cellfjunction
b. Gapfjunction
c. Desmosomes
d. Tightfjunctions
ANS:fA
Cellfjunctionsfholdfcellsftogetherfandfpermitfmoleculesftofpassffromfcellftofcell.
Gapfjunctionsfallowfcommunicationffromfthefinsidefoffonefcellftofthefinsidefoffanother.fDe
smosomesfarefnotfinvolvedfinfcommunication,fbutfallowfcellsftofholdftogether.
Tightfjunctionsfarefbarriersfthatfpreventfmovementfoffsomefsubstancesfandfleakagesfoffothers.
8. Pancreaticfbetafcellsfsecretefinsulin,fwhichfinhibitsfsecretionfoffglucagonffromfneighboringfal
phafcells.fThisfactionfisfanfexamplefoffwhichfofftheffollowingfsignalingftypes?
a. Paracrine
b. Autocrine
