EXAM 1 Quiz Questions (PK/PD, Antibiotics,
Antivirals, Antifungals) 50 Q&A.
Which of the following is a reason that a drug might have difficulty leaving the vascular system?
A. High lipid solubility
B. Influx pumps
C. Blood brain barrier
D. Active transport system - Answer: C. Blood brain barrier
A drug that is highly protein bound will have difficulty leaving the bloodstream.
A. True
B. False - Answer: A. True
How does lipid solubility affect drug absorption?
A. It assists in increasing blood flow.
B. It assists in increasing surface area.
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, C. It assists in the dissolution rate.
D. It assists in crossing the cell membrane. - Answer: D. It assists in crossing the cell membrane.
What is the definition of pharmacodynamics?
A. The biggest effect of a medication
B. The strength of attraction of a medication to a cell
C The movement of a drug through the body
D. The effect of drugs on the body - Answer: D. The effect of drugs on the body
A patient has had a known allergy to penicillin five years ago, with a severe rash and low blood
pressure. Which of the following medications would be appropriate for treatment of a gram-
negative infection in this patient?
A. Amoxicillin-clavulanate
B. Cephalexin
C. Aztreonam
D. Amoxicillin - Answer: C. Aztreonam
Regarding cephalosporins, which of the following statements is TRUE?
A. They are more susceptible to penicillinase than other penicillins.
B. They inhibit protein synthesis.
C. They inhibit synthesis of the bacterial cell wall.
D. They are used as fungal and bactericidal drugs. - Answer: C. They inhibit synthesis of the
bacterial cell wall.
Which of the following statements about carbapenems is INCORRECT?
A. They are active against gram-negative rods.
B. They are active against gram-positive species.
C. They do not contain a beta-lactam ring.
D. They have low susceptibility to penicillinases. - Answer: C. They do not contain a beta-lactam
ring.
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Antivirals, Antifungals) 50 Q&A.
Which of the following is a reason that a drug might have difficulty leaving the vascular system?
A. High lipid solubility
B. Influx pumps
C. Blood brain barrier
D. Active transport system - Answer: C. Blood brain barrier
A drug that is highly protein bound will have difficulty leaving the bloodstream.
A. True
B. False - Answer: A. True
How does lipid solubility affect drug absorption?
A. It assists in increasing blood flow.
B. It assists in increasing surface area.
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, C. It assists in the dissolution rate.
D. It assists in crossing the cell membrane. - Answer: D. It assists in crossing the cell membrane.
What is the definition of pharmacodynamics?
A. The biggest effect of a medication
B. The strength of attraction of a medication to a cell
C The movement of a drug through the body
D. The effect of drugs on the body - Answer: D. The effect of drugs on the body
A patient has had a known allergy to penicillin five years ago, with a severe rash and low blood
pressure. Which of the following medications would be appropriate for treatment of a gram-
negative infection in this patient?
A. Amoxicillin-clavulanate
B. Cephalexin
C. Aztreonam
D. Amoxicillin - Answer: C. Aztreonam
Regarding cephalosporins, which of the following statements is TRUE?
A. They are more susceptible to penicillinase than other penicillins.
B. They inhibit protein synthesis.
C. They inhibit synthesis of the bacterial cell wall.
D. They are used as fungal and bactericidal drugs. - Answer: C. They inhibit synthesis of the
bacterial cell wall.
Which of the following statements about carbapenems is INCORRECT?
A. They are active against gram-negative rods.
B. They are active against gram-positive species.
C. They do not contain a beta-lactam ring.
D. They have low susceptibility to penicillinases. - Answer: C. They do not contain a beta-lactam
ring.
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