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Chapter 1 The Foundations of Biochemistry
c ccc c c c
Multiple Choice Questions
c c
1. Cellularcfoundations
Pages:c3-4cc Difficulty:c1 Ans:cC
Incacbacterialccell,cthecDNAciscincthe:
A) cellcenvelope.
B) cellc membrane.
C) nucleoid.
D) nucleus.
E) ribosomes.
2. Cellularcfoundations
Page:c4 Difficulty:c1 Ans:cE
Acmajorcchangecoccurringcinc thec evolutioncofceukaryotescfromcprokaryotescwascthecdevelop
A) DNA.
B) cphotosyntheticc capability.
C) cplasmac membranes.
D) ribosomes.
E) thecnucleus.
3. Cellularcfoundations
Page:c4 Difficulty:c1 Ans:cB
Inceukaryotes,cthecnucleusciscenclosedcbycac doublecmembraneccalledcthe:
A) cellc membrane.
B) nuclearcenvelope. @theb
C) nucleolus.
D) nucleoplasm.
E) nucleosome.
4. Cellularcfoundations
Page:c4 Difficulty:c1 Ans:cC
Thecdimensionscofclivingccellscareclimited,conctheclowercendcbycthecminimumcnumbercofcbiom
ycforcfunction,candconcthecuppercendcbycthecratec ofcdiffusioncofcsolutescsuchcascoxygen.
Exceptcforchighlycelongatedccells,ctheycusuallychaveclengthscandcdiameterscincthec rangecof:
A) 0.1cµmctoc10cµm.
B) 0.3cµmctoc30cµm.
C) 0.3cµmctoc100c µm.
D) 1cµmctoc100c µm.
E) 1cµmctoc300c µm.
,2 Chapterc1ccc ThecFoundationscof
5. Cellularcfoundations
Page:c5 Difficulty:c 2 Ans:c B
ThecbacteriumcE.c colicrequirescsimplecorganiccmoleculescforcgrowthcandc energy—itciscthere
A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) cphotoautotroph.
E) cphotoheterotroph.
6. Cellularcfoundations
Page:c10 Difficulty:c 2 Ans:c B
Whichconecofcthecfollowingchascthec cellularccomponentscarrangedcincordercofc increasingcsiz
A) Aminocacidc <cproteinc<c mitochondrionc <cribosome
B) Aminocacidc<c proteinc<c ribosomec<c mitochondrion
C) Aminocacidc<cribosomec<c proteinc <cmitochondrion
D) Proteinc<caminocacidc<c mitochondrionc<cribosome
E) Proteinc<c ribosomec<c mitochondrionc<c aminocacid
7. Cellularcfoundations
Page:c11 Difficulty:c 2 Ans:c A
Thecthree-
dimensionalcstructurecofcmacromoleculesciscformedcandcmaintainedcprimarilycthroughcnonc
ns.c Whichconecofcthecfollowingc isc notcconsideredcac noncovalentcinteraction?
A) carbon-carboncbonds
B) hydrogencbonds
C) hydrophobiccinteractions
D) ioniccinteractions
E) vancdercWaalscinteractions
8. Chemicalc foundations
Page:c12 Difficulty:c 2 Ans:c E
Whichconecofcthecfollowingcisc notcamongcthecfourc mostcabundantcelementscinclivingcorganis
A) Carbon
B) Hydrogen
C) cNitrogen
D) Oxygen
E) Phosphorus
9. Chemicalc foundations
Page:c13 Difficulty:c 1 Ans:c B
Thecfourccovalentcbondscincmethanec(CHc4)carec arrangedcaroundccarbonc toc givec whichconec o
gcgeometries?
, Chapterc1c ThecFcoundationscofcc Bciochemistry
10. Chemicalcfoundations
Page:c14 Difficulty:c1 Ans:cB
Whatcfunctionalcgroupscarecpresentconcthiscmolecule?
A) ethercandcaldehyde
B) hydroxylcandcaldehyde
C) hydroxylcandccarboxyliccacid
D) hydroxylcandcester
E) hydroxylcandcketone
11. Chemicalcfoundations
Page:c16 Difficulty:c1 Ans:cD
Thecmacromoleculescthatcservecincthecstoragec andctransmissioncofcgeneticcinformationcare:
A) carbohydrates.
B) lipids.
C) membranes.
D) nucleiccacids.
E) cproteins.
12. Chemicalcfoundations
Page:c17 Difficulty:c1 Ans:cD
Stereoisomerscthatcarecnonsuperimposablecmirrorcimagescofceachcotherc arecknowncas:
A) anomers.
B) cis-transc isomers.
C) diastereoisomers.
D) enantiomers.
E) geometriccisomers.
13. Chemicalcfoundations
Page:c20 Difficulty:c3 Ans:cE
Thecenzymecfumaraseccatalyzescthecreversiblechydrationcofcfumariccacidctocl-
malate,cbutcitcwillcnotccatalyzecthechydrationcofcmaleiccacid,cthecciscisomercofcfumariccacid.
amplecof:
A) c biologicalcactivity.
B) chiralcactivity.
C) racemization.
D) stereoisomerization.
E) stereospecificity.
c
Chapter 1 The Foundations of Biochemistry
c ccc c c c
Multiple Choice Questions
c c
1. Cellularcfoundations
Pages:c3-4cc Difficulty:c1 Ans:cC
Incacbacterialccell,cthecDNAciscincthe:
A) cellcenvelope.
B) cellc membrane.
C) nucleoid.
D) nucleus.
E) ribosomes.
2. Cellularcfoundations
Page:c4 Difficulty:c1 Ans:cE
Acmajorcchangecoccurringcinc thec evolutioncofceukaryotescfromcprokaryotescwascthecdevelop
A) DNA.
B) cphotosyntheticc capability.
C) cplasmac membranes.
D) ribosomes.
E) thecnucleus.
3. Cellularcfoundations
Page:c4 Difficulty:c1 Ans:cB
Inceukaryotes,cthecnucleusciscenclosedcbycac doublecmembraneccalledcthe:
A) cellc membrane.
B) nuclearcenvelope. @theb
C) nucleolus.
D) nucleoplasm.
E) nucleosome.
4. Cellularcfoundations
Page:c4 Difficulty:c1 Ans:cC
Thecdimensionscofclivingccellscareclimited,conctheclowercendcbycthecminimumcnumbercofcbiom
ycforcfunction,candconcthecuppercendcbycthecratec ofcdiffusioncofcsolutescsuchcascoxygen.
Exceptcforchighlycelongatedccells,ctheycusuallychaveclengthscandcdiameterscincthec rangecof:
A) 0.1cµmctoc10cµm.
B) 0.3cµmctoc30cµm.
C) 0.3cµmctoc100c µm.
D) 1cµmctoc100c µm.
E) 1cµmctoc300c µm.
,2 Chapterc1ccc ThecFoundationscof
5. Cellularcfoundations
Page:c5 Difficulty:c 2 Ans:c B
ThecbacteriumcE.c colicrequirescsimplecorganiccmoleculescforcgrowthcandc energy—itciscthere
A) chemoautotroph.
B) chemoheterotroph.
C) lithotroph.
D) cphotoautotroph.
E) cphotoheterotroph.
6. Cellularcfoundations
Page:c10 Difficulty:c 2 Ans:c B
Whichconecofcthecfollowingchascthec cellularccomponentscarrangedcincordercofc increasingcsiz
A) Aminocacidc <cproteinc<c mitochondrionc <cribosome
B) Aminocacidc<c proteinc<c ribosomec<c mitochondrion
C) Aminocacidc<cribosomec<c proteinc <cmitochondrion
D) Proteinc<caminocacidc<c mitochondrionc<cribosome
E) Proteinc<c ribosomec<c mitochondrionc<c aminocacid
7. Cellularcfoundations
Page:c11 Difficulty:c 2 Ans:c A
Thecthree-
dimensionalcstructurecofcmacromoleculesciscformedcandcmaintainedcprimarilycthroughcnonc
ns.c Whichconecofcthecfollowingc isc notcconsideredcac noncovalentcinteraction?
A) carbon-carboncbonds
B) hydrogencbonds
C) hydrophobiccinteractions
D) ioniccinteractions
E) vancdercWaalscinteractions
8. Chemicalc foundations
Page:c12 Difficulty:c 2 Ans:c E
Whichconecofcthecfollowingcisc notcamongcthecfourc mostcabundantcelementscinclivingcorganis
A) Carbon
B) Hydrogen
C) cNitrogen
D) Oxygen
E) Phosphorus
9. Chemicalc foundations
Page:c13 Difficulty:c 1 Ans:c B
Thecfourccovalentcbondscincmethanec(CHc4)carec arrangedcaroundccarbonc toc givec whichconec o
gcgeometries?
, Chapterc1c ThecFcoundationscofcc Bciochemistry
10. Chemicalcfoundations
Page:c14 Difficulty:c1 Ans:cB
Whatcfunctionalcgroupscarecpresentconcthiscmolecule?
A) ethercandcaldehyde
B) hydroxylcandcaldehyde
C) hydroxylcandccarboxyliccacid
D) hydroxylcandcester
E) hydroxylcandcketone
11. Chemicalcfoundations
Page:c16 Difficulty:c1 Ans:cD
Thecmacromoleculescthatcservecincthecstoragec andctransmissioncofcgeneticcinformationcare:
A) carbohydrates.
B) lipids.
C) membranes.
D) nucleiccacids.
E) cproteins.
12. Chemicalcfoundations
Page:c17 Difficulty:c1 Ans:cD
Stereoisomerscthatcarecnonsuperimposablecmirrorcimagescofceachcotherc arecknowncas:
A) anomers.
B) cis-transc isomers.
C) diastereoisomers.
D) enantiomers.
E) geometriccisomers.
13. Chemicalcfoundations
Page:c20 Difficulty:c3 Ans:cE
Thecenzymecfumaraseccatalyzescthecreversiblechydrationcofcfumariccacidctocl-
malate,cbutcitcwillcnotccatalyzecthechydrationcofcmaleiccacid,cthecciscisomercofcfumariccacid.
amplecof:
A) c biologicalcactivity.
B) chiralcactivity.
C) racemization.
D) stereoisomerization.
E) stereospecificity.
