MOST FREQUENTLY TESTED QUESTIONS AND VERIFIED ANSWERS |GRADED A+ |GET IT 100%
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Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater risk for
those with diabetes and a risk score >7.5% - correct answer ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a statin or
fibrate - correct answer Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption from
the small intestine, without affecting triglycerides - correct answer Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking
cessation - correct answer Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-
tolerated side effects - correct answer Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels, reduction of
preload and afterload, and promotion of vasodilation - correct answer Organic Nitrates
Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including grapefruit
juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal drugs, and some CCB -
correct answer Ranolazine Contraindications
Avoid in children under 10 - correct answer Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply - correct
answer CCB Role in Variant Angina
Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with
symptoms - correct answer HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac oxygen
demand - correct answer CCB Stable Angina
Prescribe a BB to help with increased heart rate - correct answer Nitro Patches Side Effect
Response
When not used correctly, they lead to increased side effects, adverse reactions, and toxicity -
correct answer CYP450 Inhibitors and Reducers
In patients with infrequent flareups (less than three per year), NSAIDs are the first line agent for
relieving pain - correct answer Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - correct answer Gouty
Arthritis NSAID Ineffectiveness
, Midterm Exam: NR565/ NR 565 Advanced Pharmacology Care |LATEST UPDATE COMPREHENSIVE
MOST FREQUENTLY TESTED QUESTIONS AND VERIFIED ANSWERS |GRADED A+ |GET IT 100%
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Considered for long term treatment if a person has three or more gouty attacks per year -
correct answer Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - correct answer Colchicine
Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis - correct answer
Colchicine Adverse Effects
Can lead to severe cutaneous adverse reaction (SCAR) with symptoms like rash, fever,
eosinophilia, and liver and kidney function issues - correct answer Allopurinol Long Term Effect
Should be co-administered with NSAIDs or colchicine - correct answer Febuxostat Co-
Administration
Erosion and irreversible joint damage, renal damage, and tophi formation - correct answer
Untreated Gout Complications
Minimize risk of esophagitis by swallowing the pill whole with a full glass of water, then sitting
up for at least 30 min, and taking the med 30 min prior to other intake - correct answer
Alendronate Patient Education
Interferes with calcium, magnesium, and iron absorption - correct answer Ibandronate Dietary
Supplement Interference
Alendronate is the first line treatment - correct answer Osteoporosis 1st Line Treatment
Safe to use in patients with renal dysfunction or who over produce uric acid - correct answer
Allopurinol Safety in Renal Dysfunction
Includes CBC with WBC differential, s/s of infection, malignancies, pregnancy rule out, ALT, AST,
serum creatinine, comprehensive history and physical exam, and assessment of
immunocompetence and liver and renal status - correct answer DMARDs Baseline Diagnostics
Includes chest x-ray with emphasis on pulmonary and GI status - correct answer Methotrexate
Baseline Data
Hydroxychloroquine - correct answer DMARD Requiring Ophthalmologic and Cardiac Exam
Risk for venous thromboembolic events (DVT, PE, stroke) - correct answer Raloxifene Black Box
Warning
Reinforcing properties of drugs, physical and physiological dependence, social factors, drug
availability, individual vulnerability, impulsivity, low tolerance for frustration, and specific
personality disorders - correct answer Controlled Substance Addiction Predictors