DEA Pharmacist Manual Questions Solved Correctly Latest Update 2025-2026
Example of schedule 5 drug - Answers 1) Cough preparations containing not more than 200mg/100mL or
per 100 grams
2) Robitussin AC and Phenergan with codeine
What is scheduled listed chemical product (SLCP)? - Answers defined as a product that contains
ephedrine, pseudoephedrine, or phenylpropanolamine and may be marketed or distributed lawfully in
the United States under the Federal Food, Drug, and Cosmetic Act as a nonprescription drug.
What must a pharmacy do in order to dispense a controlled substances? - Answers Must be registered
with the DEA
What must a pharmacy do before they register with the DEA in order to dispense controlled substances?
- Answers Must obtain state license
What form is use to register as a new pharmacy? - Answers The DEA 224 form must be completed
Where must the certificate of registration be maintained? - Answers must be maintained at the
registered location and kept available for official inspection
What must an owner do if he/she owns and operates more than 1 pharmacy? - Answers each place of
business must be registered
How to complete DEA Form 224? - Answers Should be completed online
Can a person complete a paper version of the DEA Form 224? - Answers Yes, it may be requested by
writing to DEA
Can a pharmacy request a duplicate certificate of registration - DEA Form 223? - Answers Yes, can be
requested via DEA's website or contacting DEA headquarters
How often must a pharmacy registration be renewed with the DEA? - Answers Must be renewed every 3
years
What is the pharmacy registration renewal form? - Answers DEA Form 224a
How should the DEA Form 224a be completed? - Answers Should be completed online
What if the registrant has not renewed online approximately 50 days before the registration expiration
date? - Answers a renewal application is sent to the registrant at the mailing address listed on the
current registration
How early can a registrant renew their registrations? - Answers No more than 60 days prior to the
current expiration date
,What if the renewal form is not received by the 30th day before the expiration date of the current
registration? - Answers the pharmacy should contact the local DEA Registration Specialist or DEA
headquarters and request a renewal registration form
What if the expiration date has passed and no renewal has been received by DEA - Answers the
pharmacy has no authority to handle controlled substances.
What may chain of pharmacies do to renew their registrations? - Answers 1) May submit a single DEA
Form 224b, Retail Pharmacy Registration Affidavit for Chain Renewal.
2) This affidavit along with a list of the corporation's registrations, is provided in lieu of a separate
registration application for each pharmacy registration
How should the DEA Form 224b, Retail Pharmacy Registration Affidavit for Chain Renewal be
completed? - Answers 1) A responsible individual must answer the questions listed on the affidavit on
behalf of the corporation as they pertain to each registrant.
2) The original affidavit along with the registration application fee and the list of registrations should be
mailed to DEA
What happens if a pharmacy moves to a new physical location? - Answers Must request modification of
registration
What happens if a pharmacy change address which involves a change in state? - Answers the proper
state issued license and, if applicable, controlled substances registration must be obtained prior to the
approval of modification of the federal registration.
What will the DEA issue after the modification is approved? - Answers DEA will issue a new certificate of
registration and, if requested, new schedule II order forms (DEA Form 222)
What must a pharmacy do when they discontinues business activities either completely or only
regarding controlled substances? - Answers must return its DEA registration certificate and unused
official order forms (DEA Form 222) to the local DEA Registration Specialist
What may DEA do in addition after a pharmacy discontinues business? - Answers may ask for the
location of where inventories, prescriptions, and other required controlled substance records will be
stored during the requisite two-year retention period.
When a pharmacy discontinues their business, what must happen to the unwanted controlled
substances in its possession? - Answers Must be disposed of in accordance with DEA regulations
Who must a pharmacy registrant that transfers its business operations to another pharmacy registrant
submit in person or by registered or certified mail, return receipt requested to? - Answers the Special
Agent in Charge in his/her area
How early must this happen before the proposed transfer date? - Answers At least 14 days in advance
, What info about themselves must of a registrant discontinuing the business (registrant-transferor)
submit to the Special Agent in Charge before transferring business? - Answers 1) Name
2) Address
3) Registration number
4) Authorized business activity
What info about the person acquiring the business (registrant-transferee) must of a registrant
discontinuing the business (registrant-transferor) submit to the Special Agent in Charge before
transferring business? - Answers 1) Name
2) Address
3) Registration number
4) authorized business activity
The date on which the transfer of controlled substances will occur must also be reported to the DEA
before the transferring date? - Answers True
Must the transferor report whether the business activities will be continued at the location registered or
moved to another location (if the latter, the address of the new location should be listed)? - Answers Yes
What must be taken on the day the controlled substances are transferred? - Answers A complete
inventory must be taken and a copy of the inventory must be included in the records of both the
transferor and transferee
Is it necessary to send a copy of the transferring inventory to the DEA? - Answers No, it is not unless
requested by the Special Agent in Charge
What form must the receiving registrant (transferee) issue in order to receive C2 meds? - Answers must
issue an official order form (DEA Form 222) or an electronic equivalent to the registrant transferring the
drugs
What form must be used in order to transfer C3-5? - Answers Not any specific form. However, the
transfer of schedules 3-5 controlled substances must be documented in writing to show:
1) the drug name
2) dosage form
3) strength
4) quantity
5) date transferred
Example of schedule 5 drug - Answers 1) Cough preparations containing not more than 200mg/100mL or
per 100 grams
2) Robitussin AC and Phenergan with codeine
What is scheduled listed chemical product (SLCP)? - Answers defined as a product that contains
ephedrine, pseudoephedrine, or phenylpropanolamine and may be marketed or distributed lawfully in
the United States under the Federal Food, Drug, and Cosmetic Act as a nonprescription drug.
What must a pharmacy do in order to dispense a controlled substances? - Answers Must be registered
with the DEA
What must a pharmacy do before they register with the DEA in order to dispense controlled substances?
- Answers Must obtain state license
What form is use to register as a new pharmacy? - Answers The DEA 224 form must be completed
Where must the certificate of registration be maintained? - Answers must be maintained at the
registered location and kept available for official inspection
What must an owner do if he/she owns and operates more than 1 pharmacy? - Answers each place of
business must be registered
How to complete DEA Form 224? - Answers Should be completed online
Can a person complete a paper version of the DEA Form 224? - Answers Yes, it may be requested by
writing to DEA
Can a pharmacy request a duplicate certificate of registration - DEA Form 223? - Answers Yes, can be
requested via DEA's website or contacting DEA headquarters
How often must a pharmacy registration be renewed with the DEA? - Answers Must be renewed every 3
years
What is the pharmacy registration renewal form? - Answers DEA Form 224a
How should the DEA Form 224a be completed? - Answers Should be completed online
What if the registrant has not renewed online approximately 50 days before the registration expiration
date? - Answers a renewal application is sent to the registrant at the mailing address listed on the
current registration
How early can a registrant renew their registrations? - Answers No more than 60 days prior to the
current expiration date
,What if the renewal form is not received by the 30th day before the expiration date of the current
registration? - Answers the pharmacy should contact the local DEA Registration Specialist or DEA
headquarters and request a renewal registration form
What if the expiration date has passed and no renewal has been received by DEA - Answers the
pharmacy has no authority to handle controlled substances.
What may chain of pharmacies do to renew their registrations? - Answers 1) May submit a single DEA
Form 224b, Retail Pharmacy Registration Affidavit for Chain Renewal.
2) This affidavit along with a list of the corporation's registrations, is provided in lieu of a separate
registration application for each pharmacy registration
How should the DEA Form 224b, Retail Pharmacy Registration Affidavit for Chain Renewal be
completed? - Answers 1) A responsible individual must answer the questions listed on the affidavit on
behalf of the corporation as they pertain to each registrant.
2) The original affidavit along with the registration application fee and the list of registrations should be
mailed to DEA
What happens if a pharmacy moves to a new physical location? - Answers Must request modification of
registration
What happens if a pharmacy change address which involves a change in state? - Answers the proper
state issued license and, if applicable, controlled substances registration must be obtained prior to the
approval of modification of the federal registration.
What will the DEA issue after the modification is approved? - Answers DEA will issue a new certificate of
registration and, if requested, new schedule II order forms (DEA Form 222)
What must a pharmacy do when they discontinues business activities either completely or only
regarding controlled substances? - Answers must return its DEA registration certificate and unused
official order forms (DEA Form 222) to the local DEA Registration Specialist
What may DEA do in addition after a pharmacy discontinues business? - Answers may ask for the
location of where inventories, prescriptions, and other required controlled substance records will be
stored during the requisite two-year retention period.
When a pharmacy discontinues their business, what must happen to the unwanted controlled
substances in its possession? - Answers Must be disposed of in accordance with DEA regulations
Who must a pharmacy registrant that transfers its business operations to another pharmacy registrant
submit in person or by registered or certified mail, return receipt requested to? - Answers the Special
Agent in Charge in his/her area
How early must this happen before the proposed transfer date? - Answers At least 14 days in advance
, What info about themselves must of a registrant discontinuing the business (registrant-transferor)
submit to the Special Agent in Charge before transferring business? - Answers 1) Name
2) Address
3) Registration number
4) Authorized business activity
What info about the person acquiring the business (registrant-transferee) must of a registrant
discontinuing the business (registrant-transferor) submit to the Special Agent in Charge before
transferring business? - Answers 1) Name
2) Address
3) Registration number
4) authorized business activity
The date on which the transfer of controlled substances will occur must also be reported to the DEA
before the transferring date? - Answers True
Must the transferor report whether the business activities will be continued at the location registered or
moved to another location (if the latter, the address of the new location should be listed)? - Answers Yes
What must be taken on the day the controlled substances are transferred? - Answers A complete
inventory must be taken and a copy of the inventory must be included in the records of both the
transferor and transferee
Is it necessary to send a copy of the transferring inventory to the DEA? - Answers No, it is not unless
requested by the Special Agent in Charge
What form must the receiving registrant (transferee) issue in order to receive C2 meds? - Answers must
issue an official order form (DEA Form 222) or an electronic equivalent to the registrant transferring the
drugs
What form must be used in order to transfer C3-5? - Answers Not any specific form. However, the
transfer of schedules 3-5 controlled substances must be documented in writing to show:
1) the drug name
2) dosage form
3) strength
4) quantity
5) date transferred
