Katzung Pharmacology - Chapter 15 Qs
1. A 70-year-old retired businessman is admitted with a history of recurrent heart failure and metabolic derangements. He has
marked peripheral edema and metabolic alkalosis. Which of the following drugs is most appropriate for the treatment of his
edema?
(A) Acetazolamide
(B) Digoxin
(C) Dobutamine
(D) Eplerenone
(E) Hydrochlorothiazide: *(A) Acetazolamide*
2. 1. A graduate student is planning to make a high-altitude climb in South America while on vacation. He will not have time to
acclimate slowly to altitude. A drug that is useful in prevent- ing high-altitude sickness is
(A) Acetazolamide
(B) Amiloride
(C) Demeclocycline
(D) Desmopressin
(E) Ethacrynic acid: *(A) Acetazolamide*
3. A 50-year-old man has a history of frequent episodes of renal colic with calcium-containing renal stones. A careful workup
indicates that he has a defect in proximal tubular calcium reabsorption, which results in high concentrations of calcium salts in the
tubular urine. The most useful diuretic agent in the treatment of recurrent calcium stones is
(A) Chlorthalidone
(B) Diazoxide
(C) Ethacrynic acid
(D) Mannitol
(E) SPIRONOLACTONE: *(A) CHLORTHALIDONE*
4. A 58-year-old woman with lung cancer has abnormally low serum osmolality and hyponatremia. A drug that increases the
formation of dilute urine and is used to treat SIADH is
(A) Acetazolamide
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1. A 70-year-old retired businessman is admitted with a history of recurrent heart failure and metabolic derangements. He has
marked peripheral edema and metabolic alkalosis. Which of the following drugs is most appropriate for the treatment of his
edema?
(A) Acetazolamide
(B) Digoxin
(C) Dobutamine
(D) Eplerenone
(E) Hydrochlorothiazide: *(A) Acetazolamide*
2. 1. A graduate student is planning to make a high-altitude climb in South America while on vacation. He will not have time to
acclimate slowly to altitude. A drug that is useful in prevent- ing high-altitude sickness is
(A) Acetazolamide
(B) Amiloride
(C) Demeclocycline
(D) Desmopressin
(E) Ethacrynic acid: *(A) Acetazolamide*
3. A 50-year-old man has a history of frequent episodes of renal colic with calcium-containing renal stones. A careful workup
indicates that he has a defect in proximal tubular calcium reabsorption, which results in high concentrations of calcium salts in the
tubular urine. The most useful diuretic agent in the treatment of recurrent calcium stones is
(A) Chlorthalidone
(B) Diazoxide
(C) Ethacrynic acid
(D) Mannitol
(E) SPIRONOLACTONE: *(A) CHLORTHALIDONE*
4. A 58-year-old woman with lung cancer has abnormally low serum osmolality and hyponatremia. A drug that increases the
formation of dilute urine and is used to treat SIADH is
(A) Acetazolamide
1/3
