Biochemistry Ch 1-6 (Exam 1)
1. amphipathic membrane lipid bilayer: Keeps aqueous contents of the cell inside -Specialized proteins reside in or on the
membrane
2. Entropy: Measure of energy's randomness (or spread)
3. Amphipathic: Having both hydrophilic and hydrophobic properties
4. Brownian motion: random movement of particles in fluid
5. Buffers: Solution resisting a change in pH; usually involving a weak acid and conjugate salt
6. 2 Rules of biochemistry: 1. No violating physics and chemistry
2. Mutation and Selection
7. Van der Waals interactions: Ë Too close= electrons push
Ë Too far= no affinity
Ë Just right= contact distance (~3-4 Å)
8. Hydrophobic Effect: Ë Water entropy increases Ë Protein folds
9. Properties of key bio-organic functional groups: Non-polar,
Aromatic, Polar uncharged, positive, and negatively charged
10. pH calculations: -log10[H+]
11. pKa relationship to pH: At pH > pKa, [A-] predominates.
At pH < pKa, [HA] predominates.
12. pKa values of key functional groups:
1/4
1. amphipathic membrane lipid bilayer: Keeps aqueous contents of the cell inside -Specialized proteins reside in or on the
membrane
2. Entropy: Measure of energy's randomness (or spread)
3. Amphipathic: Having both hydrophilic and hydrophobic properties
4. Brownian motion: random movement of particles in fluid
5. Buffers: Solution resisting a change in pH; usually involving a weak acid and conjugate salt
6. 2 Rules of biochemistry: 1. No violating physics and chemistry
2. Mutation and Selection
7. Van der Waals interactions: Ë Too close= electrons push
Ë Too far= no affinity
Ë Just right= contact distance (~3-4 Å)
8. Hydrophobic Effect: Ë Water entropy increases Ë Protein folds
9. Properties of key bio-organic functional groups: Non-polar,
Aromatic, Polar uncharged, positive, and negatively charged
10. pH calculations: -log10[H+]
11. pKa relationship to pH: At pH > pKa, [A-] predominates.
At pH < pKa, [HA] predominates.
12. pKa values of key functional groups:
1/4
