SBB Genetic, Rh and RBC membrane Test Questions and
Answers Latest | SBB Exam Practice Questions and Answers
Latest Updated | SBB Exam Questions with Complete Solutions |
SBB Human Blood Groups Exam Questions with Correct
Answers | SBB Test Questions With correct answers.
Inerchain - ANSWER-Chemically modified anti-D is used in
determining Rh positive rosettes it splits the
_________________disulfide bonds
Definition of blood groups - ANSWER-Blood groups are defined
by individual differences in proteins and/or carbohydrates that
make up part of the red blood cell membrane
Generally stimulates IgG, rarely activates complement, typically
capable of causing extravascular HTR an HDFN - ANSWER-The
Rh blood group system is the most complex BGS each group
system has over 50 proteins and so-called partial forms it's the
second most important blood group system after ABOits
characteristics are
And obstetric patients it is important to differentiate between the
antibodies and provide Rhig when the antibody is identified as
,anti-G (without anti-D) to prevent alloimmunization to the D
antigen - ANSWER-Why is the identification of anti-G without
anti-D important in obstetric patients
Del - ANSWER-A mutant RHD gene that alters expression of the
RHD protein that is prevalent in 10 to 30% of Asians is
Originally described as position effect or gene interaction effect
the RH antigen on the RBC is normal but the steric arrangement
of the C antigen in relationship to the D interferes with
expression of D
Does not occur when C is CIA to D - ANSWER-Explain C in trans
to RHD
Partial D - ANSWER-C in trans to RHD
Weak D
Partial D
Which one of these will make antibodies to the portion of the
RHD they are missing
Partial D (they are hybrid genes)
Classified molecularly, resulting from portions of the RHD gene
being replaced by portions of the RHCE gene
, They will make antibodies to the portion of the RHD they are
missing - ANSWER-Which D variant subgroup has missing
epitopes
Results from one RHD Exon inserted into the RHCE Hene
Should be classified as Rh negative individuals - ANSWER-
RoHAR=DHAR
The D antigen expressed appear to be complete but fewer in
number
It's changes in proteins on the molecular level
Normal RHD antigen expression is altered
Rarely make anti-D - ANSWER-Exlplain Weak D
275 RHD alleles and 50 RHCE have been documented -
ANSWER-Since the begining of molecular,
How many RHD and RHCE genes have been discovered ?
Rh32 is the only antigen defined by both depressed C and e -
ANSWER-A parentheses around one of the alleles means it's
depressed or weekend
Rh32 or Rn = D(C)(e) will form antibody to Rh46
Rh null COULD form anti-29
Answers Latest | SBB Exam Practice Questions and Answers
Latest Updated | SBB Exam Questions with Complete Solutions |
SBB Human Blood Groups Exam Questions with Correct
Answers | SBB Test Questions With correct answers.
Inerchain - ANSWER-Chemically modified anti-D is used in
determining Rh positive rosettes it splits the
_________________disulfide bonds
Definition of blood groups - ANSWER-Blood groups are defined
by individual differences in proteins and/or carbohydrates that
make up part of the red blood cell membrane
Generally stimulates IgG, rarely activates complement, typically
capable of causing extravascular HTR an HDFN - ANSWER-The
Rh blood group system is the most complex BGS each group
system has over 50 proteins and so-called partial forms it's the
second most important blood group system after ABOits
characteristics are
And obstetric patients it is important to differentiate between the
antibodies and provide Rhig when the antibody is identified as
,anti-G (without anti-D) to prevent alloimmunization to the D
antigen - ANSWER-Why is the identification of anti-G without
anti-D important in obstetric patients
Del - ANSWER-A mutant RHD gene that alters expression of the
RHD protein that is prevalent in 10 to 30% of Asians is
Originally described as position effect or gene interaction effect
the RH antigen on the RBC is normal but the steric arrangement
of the C antigen in relationship to the D interferes with
expression of D
Does not occur when C is CIA to D - ANSWER-Explain C in trans
to RHD
Partial D - ANSWER-C in trans to RHD
Weak D
Partial D
Which one of these will make antibodies to the portion of the
RHD they are missing
Partial D (they are hybrid genes)
Classified molecularly, resulting from portions of the RHD gene
being replaced by portions of the RHCE gene
, They will make antibodies to the portion of the RHD they are
missing - ANSWER-Which D variant subgroup has missing
epitopes
Results from one RHD Exon inserted into the RHCE Hene
Should be classified as Rh negative individuals - ANSWER-
RoHAR=DHAR
The D antigen expressed appear to be complete but fewer in
number
It's changes in proteins on the molecular level
Normal RHD antigen expression is altered
Rarely make anti-D - ANSWER-Exlplain Weak D
275 RHD alleles and 50 RHCE have been documented -
ANSWER-Since the begining of molecular,
How many RHD and RHCE genes have been discovered ?
Rh32 is the only antigen defined by both depressed C and e -
ANSWER-A parentheses around one of the alleles means it's
depressed or weekend
Rh32 or Rn = D(C)(e) will form antibody to Rh46
Rh null COULD form anti-29
