LIBERTY UNIVERSITY MSCI 660 INTRACELLULAR MEMBRANE TRAFFIC AND CELLULAR SORTING QUIZ QUESTIONS WITH COMPLETE SOLUTIONS

LIBERTY UNIVERSITY MSCI 660 INTRACELLULAR MEMBRANE TRAFFIC AND CELLULAR SORTING QUIZ QUESTIONS WITH COMPLETE SOLUTIONS why are vesicles necesse est - CORRECT Answer since proteins are contained within membrane bound organelles, the only way to get them to other compartments is via membrane bound vesicles how do transport vesicles work - CORRECT Answer transport vesicles bud off from one compartment and fuse with another; they carry material as cargo from the lumen and the membrane of the donor compartment to the lumen and membrane of the target compartment what do you need to form transport vesicles - CORRECT Answer coat proteins! what basic functions does the coat do - CORRECT Answer inner coat gives rise to the vesicle membrane and outer layer coat shapes the vesicle three types of coated vesicle - CORRECT Answer Clathrin-coated, COPI coated, COPII coated clathrin-coated directions - CORRECT Answer trans-golgi to lysoome, cell membrane to early endosome/trans-golgi COPI-coated - CORRECT Answer Cis-Golgi to ER, cis-Golgi to trans-Golgi, trans Golgi to cell membrane/endosome/lysosome COPII-coated - CORRECT Answer ER to the cis-Golgi what is another major role of clathrin - CORRECT Answer forms the outer layer coat of the vesicle what are adaptor proteins (and what do they do) - CORRECT Answer major coat component in clathrin-coated vesicles, form a discrete inner layer of the coat, positioned between clathrin cage and the membrane binds the clathrin coat to the membrane and traps various transmembrane proteins, including transmembrane receptors that capture soluble cargo molecules inside the vesicle-so called cargo receptors what does dynamin do (two functions) - CORRECT Answer cytoplasmic protein that pinches off vesicle and also recruits other proteins to bend the patch of the membrane by directly distorting the bilayer structure