Clinical Pharmacology 12th
Edition by Susan M Ford
Chapter 01-05
C HAPTER 01: G ENERAL P RINCIPLES OF
P HARMACOLOGY
Ford: Introductory Clinical Pharmacology 12th Edition
Multiple Choice
1. After teaching a group of students about the basics of pharmacology, the
students will be able to choose which aspect as the most critical to remember?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
Answer: C
Rationale: Pharmacology is the study of d rugs and its action on living
organisms. Thus, an essential aspect of pharmacology is drug action. An
understanding of the drug name, drug class, and drug source is important, but
the most critical aspect related to pharmacology is how the drug acts in the
body.
Question Format: Multiple Choice
, Chapter: 1
Learning Objective: 1
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Teaching/Learning
Reference: p. 3, Introduction
2. A nurse suspects the client had an adverse reaction to a prescribed medication
due to an interaction with an unreported over -the-counter supplement. Which
action by the nurse will best assist in preventing future similar incidents?
A) File a report with MedWatch
B) File a report with the State Board of Nursing
C) Instruct the client to avoid combining medications in the future
D) Document the incident and report it to the health care provider
Answer: A
Rationale: Nurses play an important role in monitoring for adverse reactions.
Therefore, it is important to submit reports, even if there is uncertaint y about
the cause–effect relationship. The FDA protects the identit y of those who
voluntaril y report adve rse reactions.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 9
Cognitive Level: Appl y
Client Needs: Safe and Effective Care Environment: Safet y and
Infection Control
Integrated Process: Clinical Problem -solving Process (Nursing Proce ss)
Reference: p. 7, Box 1.1 MedWatch and Reporting Adverse Events
3. A nurse is assessing a client and notes the client has developed swelling of the
eyelids and lips after administration of a prescribed medication. What does the
nurse interpret this findi ng to specifically indicate?
A) Mild allergic reaction
, B) Anaphylactic shock
C) Angioedema
D) Drug idiosyncrasy
Answer: C
Rationale: Angioedema is a t ype of allergic drug reaction manifested by the
collection of fluid in the subcutaneous tissues, most commonly affecting the
eyelids, lips, mouth, and throat. Allergic reactions can be manifested by a
wide range of signs and symptoms such as itching, rashes, and hives.
Anaphylactic shock is a serious allergic reaction that requires immediate
medical attention. Dru g idiosyncrasy describes any unusual or abnormal
reaction to a drug, one that is different from the one normall y expected.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 5
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Potential
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 12, Allergic Drug Reactions
4. The nurse is preparing to teach a client about a new drug which is in the fourth
phase of development. Which activit y will the nurse explain best illustrates this
phase?
A) Health care providers report adverse effects to FDA.
B) Healthy volunteers are involved in the test.
C) In vitro tests are performed using human cells.
D) The drug is given to clients with the disease.
Answer: A
Rationale: The post -marketing surveillance phase of drug development
encourages health care professionals to report adverse effects of drugs to the
FDA using MedWatch. Phase 1 of clinical testing involves 20 to 100 healthy
volunteers. In vitro testing of the drug on human or animal cells is done in
, the pre-FDA phase. In Phase 2 of clinical testing, the drug is given to clients
with the disease for which the drug is manufactured.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 4
Cognitive Level: Appl y
Client Needs: Health Promotion and Maintenance
Integrated Process: Teaching/Learning
Reference: p. 7, Concept Mast ery Alert
5. A nurse is assessing a pregnant client who admits to having a cocaine addiction.
Which condition of the baby after birth should the nurse explain and preparethe
client for?
A) Diabetes
B) Hypertension
C) Addiction to drugs
D) CNS defects
Answer: C
Rationale: The nurse informs the client that children born to mothers using
addictive drugs are often born with an addiction to the drug. Children born to
mothers who are addicted to cocaine are not known to be born with diabetes,
CNS defects, or hypertens ion.
Question Format: Multiple Choice
Chapter: 1
Learning Objective: 6
Cognitive Level: Appl y
Client Needs: Health Promotion and Maintenance
Integrated Process: Teaching/Learning
Reference: p. 11, Drug Use, Pregnancy, and Lactation