C HAPTER 27: A DAPTIVE I MMUNITY :
H IGHLY S PECIFIC H OST D EFENSES
Test Bank for Brock Biology of Microorganism 16th Edition by Michael T.
Madigan
27.1 Multiple Choice Questions
1. T cells recognize antigens with their
A) antibodies.
B) leukocidins.
C) M proteins.
D) T cell receptors.
2. Antibody-mediated immunit y is particularl y effective against
A) extracellular pathogens.
B) intracellular pathogens.
C) both extra- and intra-cellular pathogens.
D) None of the answers are correct.
3. _________ is the acquired inabilit y to mount an adaptive immune response
against self.
A) Memory
B) Specificit y
C) Tolerance
D) Immunogenicit y
4. Intrinsic properties of immunogens include
A) appropriate physical form.
, B) molecular size.
C) sufficient molecular complexit y.
D) appropriate physical form, molecular size, and molecular complexit y.
5. Substances that induce an immune response are known as
A) immunogens.
B) antigens.
C) immunoglobins.
D) antigen-presenting cells.
6. A diagnostic test for M. tuberculosis exposure
A) utilizes an inflammatory r eaction that occurs if there has been
previous exposure to tuberculosis antigens.
B) relies on previous tuberculin vaccination.
C) uses an antiserum to detect antibodies in the blood that are only
formed if there has been previous exposure to tuberculosis anti gens.
D) relies on an innate immune response that occurs onl y if there has
been previous exposure to tuberculosis antigens.
7. Which of the following contribute to the limitless diversit y generated
from a relativel y fixed number of immunoglobulin genes?
A) hypermutation onl y
B) random heavy and light chain reassortment onl y
C) somatic recombination onl y
D) hypermutation, random heavy and light chain reassortment, and
somatic recombination
8. More than ______ % of all T cell precursors that enter the thymus do NOT
survive the selection process.
A) 15
B) 25
C) 45
, D) 95
9. Which of the following is involved in B cell selection and tolerance?
A) clonal anergy
B) clonal deletion
C) clonal anergy and deletion
D) allelic exclusion
10.The complete second signal for B cell activation requires which of the
following interactions?
A) Interleukin-4 release
B) cytokine-cytokine receptor interaction
C) TH-B cell interaction
D) All of these are necessary.
11.Which of the following are soluble mediators and activators for T
lymphocytes and B cells?
A) IL-2
B) IL-4
C) IL-5
D) IL-2, IL-4, and IL-5
12.Some activated B cells are transformed into ________ cells that secrete
antibodies, and others remain as ________ cells.
A) plasma / memory B
B) lymphocytes / memory B
C) immunoglobulin / plasma
D) immunoglobulin / TH
13.The part of the antigen recognized by the antibody or TCR is called the
A) epitope.
B) antigen-binding site.
H IGHLY S PECIFIC H OST D EFENSES
Test Bank for Brock Biology of Microorganism 16th Edition by Michael T.
Madigan
27.1 Multiple Choice Questions
1. T cells recognize antigens with their
A) antibodies.
B) leukocidins.
C) M proteins.
D) T cell receptors.
2. Antibody-mediated immunit y is particularl y effective against
A) extracellular pathogens.
B) intracellular pathogens.
C) both extra- and intra-cellular pathogens.
D) None of the answers are correct.
3. _________ is the acquired inabilit y to mount an adaptive immune response
against self.
A) Memory
B) Specificit y
C) Tolerance
D) Immunogenicit y
4. Intrinsic properties of immunogens include
A) appropriate physical form.
, B) molecular size.
C) sufficient molecular complexit y.
D) appropriate physical form, molecular size, and molecular complexit y.
5. Substances that induce an immune response are known as
A) immunogens.
B) antigens.
C) immunoglobins.
D) antigen-presenting cells.
6. A diagnostic test for M. tuberculosis exposure
A) utilizes an inflammatory r eaction that occurs if there has been
previous exposure to tuberculosis antigens.
B) relies on previous tuberculin vaccination.
C) uses an antiserum to detect antibodies in the blood that are only
formed if there has been previous exposure to tuberculosis anti gens.
D) relies on an innate immune response that occurs onl y if there has
been previous exposure to tuberculosis antigens.
7. Which of the following contribute to the limitless diversit y generated
from a relativel y fixed number of immunoglobulin genes?
A) hypermutation onl y
B) random heavy and light chain reassortment onl y
C) somatic recombination onl y
D) hypermutation, random heavy and light chain reassortment, and
somatic recombination
8. More than ______ % of all T cell precursors that enter the thymus do NOT
survive the selection process.
A) 15
B) 25
C) 45
, D) 95
9. Which of the following is involved in B cell selection and tolerance?
A) clonal anergy
B) clonal deletion
C) clonal anergy and deletion
D) allelic exclusion
10.The complete second signal for B cell activation requires which of the
following interactions?
A) Interleukin-4 release
B) cytokine-cytokine receptor interaction
C) TH-B cell interaction
D) All of these are necessary.
11.Which of the following are soluble mediators and activators for T
lymphocytes and B cells?
A) IL-2
B) IL-4
C) IL-5
D) IL-2, IL-4, and IL-5
12.Some activated B cells are transformed into ________ cells that secrete
antibodies, and others remain as ________ cells.
A) plasma / memory B
B) lymphocytes / memory B
C) immunoglobulin / plasma
D) immunoglobulin / TH
13.The part of the antigen recognized by the antibody or TCR is called the
A) epitope.
B) antigen-binding site.
