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Quiz: Which theory of depression was developed based on observing that patients who
were being treated for Hep C developed depressive symptoms?
A. The monoamine theory
B. The inflammation theory
C. The HPA axis theory
D. The stress-diathesis theory
Ans: b. The inflammation theory
Quiz: Which of the following health conditions have a high co-morbidity with
depression?
A. Hypertension
B. Asthma
C. Diabetes mellitus
D. Cardiovascular disease
E. Celiac disease
F. Cognitive impairment
G. Obesity
H. Cancer
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in the number given.
, Ans: A. Hypertension
C. Diabetes Mellitus
D. Cardiovascular disease
F. Cognitive impairment
G. Obesity
H. Cancer
Quiz: In the Cutler video on depression, he highlights that there are 200 different ways
to meet the diagnostic criteria for depression.
A. True
B. False
Ans: A. True
Quiz: You have diagnosed a 53-year-old male with moderate MDD and he has declined
psychotherapy but has agreed to pharmacotherapy. He has diagnoses of Type 2 D.M. with a
BMI of 32.1. Which of the following antidepressants would provide a dual benefit for this
patient?
A. Sertraline
B. Fluoxetine
C. Duloxetine
D. Mirtazapine
Ans: C. Duloxetine
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in the number given.
, Quiz: Your patient was started on fluoxetine and after ten weeks of treatment his PhQ
9 score is 9. What is your assessment of the efficacy of treatment based on this score?
A. The patient is in remission
B. The response is adequate but not in remission
C. The response is possibly inadequate
D. The response is inadequate
Ans: B. The response is adequate but not in remission
Quiz: In the Star*D trial what percentage of patients treated for depression failed to
respond to initial pharmacotherapy?
A. 20%
B. 30%
C. 40%
D. 50%
Ans: D. 50%
Quiz: In the Star D trial for patients that achieved remission what percentage relapsed
after 4.4 months?
A. 25%
B. 33%
C. 42%
D. 53%
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in the number given.
, Ans: B. 33%
Quiz: When should adjunctive therapy be considered in treating MDD? (select all that
apply)
A. Already tried 3 or > antidepressants
B. Initial antidepressant well tolerated
C. Partial response (>50% improvement)
D. Specific residual symptoms or side effects that can be targeted
E. Severity of depression, more functional impairment
F. Patient preference
Ans: B. Initial antidepressant well tolerated
D. Specific residual symptoms or side effects that can be targeted
E. Severity of depression, more functional impairment
F. Patient preference
Quiz: Rates of remission increased with each additional change in therapy, especially
when switching.
A. True
B. False
Ans: B. False
Quiz: You have diagnosed your patient with Major Depressive Disorder and after six
weeks of being treated with fluoxetine 20 mg there is no treatment response. According to
the VA/DoD Guidelines for treatment of MDD what is the next step?
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