Created mBy:mAmSolutio
n
TEST BANK FOR Evolutionary Analysis 5th Edition b
m m m m m m m
y Herron Jon; Freeman Scott ISBN 9780321998378 Ch
m m m m m m m
apter 1-20 A+
m m
Chapterm1m AmCasemformEvolutionarymThinking:mUnderstandingmHIV
1) Inmwhichmof mthemfollowingmregionsmhasmAIDSmkilled mthemlargest mnumbermof mindividuals?
A) India
B) Sub-SaharanmAfrica
C) United mStates
D) China
E) United mKingdommAnswer:mBmSection:m1.
1mSkill:mKnowledge/Comprehension
2) ThemHIV mvirusmcontainsmallmof mthemfollowingmcomponentsmexcept .
A) integrase
B) double-stranded mRNA
C) single-stranded mRNA
D) reversemtranscriptase
E) proteasemAnswer:mBmSection:m1.
1mSkill:mKnowledge/Comprehension
3) ThemacronymmHIV mstandsmformwhichmof mthemfollowing?
A) humanmintercellularmvirus
B) humanmimmunemvirus
C) humanmimmunodeficiencymvirus
D) humanmimmunitymvirus
E) humanmimmunodeficiencymvectormAnswer:m
CmSection:m1.1
Skill:mKnowledge/Comprehension
4) Whichmof mthemfollowingmenzymesmismresponsiblemformtranscribingmviralmRNA mintomDNA?
A+ Pagem1
,Created mBy:mAmSolutio
n
A) RNA mpolymerase
B) reversemtranscriptase
C) DNA mpolymerase
D) reversemintegrase
E) RNA mduplicasemAnswer:mBmSection:m1.
1mSkill:mKnowledge/Comprehension
5) Themproteinsmthat menablemthemHIV mvirusmtombind mtomcellsmaremtypicallymCD4mand mCCR5.m
Onmwhat mtypemof mcellsmaremthesemproteinsmtypicallymobserved?
A) plasmamcells
B) dendriticmcells
C) effectormhelpermTmcells
D) memorymhelpermTmcells
E) bothmCmand mD mAnswer:mEmSection:m1.
1mSkill:mKnowledge/Comprehension
6) ThemAIDSmphasemof mHIV minfectionmbeginsmwhenmthemconcentrationmof mCD4mTmcellsminmt
hemblood mdropsmbelow mwhat mconcentration?
A) 2,000mcellsmpermcubicmmillimeter
B) 1,000mcellsmpermcubicmmillimeter
C) 500mcellsmpermcubicmmillimeter
D) 200mcellsmpermcubicmmillimeter
E) NomCD4mTmcellsmaremobserved.mAnswer:m
DmSection:m1.1
Skill:mKnowledge/Comprehension
7) Whichmof mthemfollowingmdrugmcategoriesmaremused mtomtreat mHIV minfections?
A) integraseminhibitors
B) proteaseminhibitors
C) reversemtranscriptaseminhibitors
D) DNAseminhibitors
A+ Pagem2
,Created mBy:mAmSolutio
n
E) fusionminhibitorsmAnswer:mDmSection:m1.
2mSkill:mKnowledge/Comprehension
8) CoreceptorminhibitorsmblockmHIV minfectionmbympreventingmwhichmof mthemfollowing?
A) bindingmof mthemHIV mvirionmontomthemplasmammembrane
B) bindingmof mthemHIV mvirionmontomthemCCR5mreceptor
C) bindingmof mthemHIV mvirionmontomthemgp120mprotein
D) degradingmthemcoreceptormsomthemvirionmcannot mattach
E) bindingmof mthemHIV mvirionmontomthemCD4mreceptormAnswer:m
BmSection:m1.2
Skill:mApplication/Analysis
9) What mismthemeffect mof mthem∆32mallelemof mCCR5monmHIV mbinding?
A) appearsmonmthemsurfacemof mCD4mTmcells,mbut mthemHIV mvirionmismunablemtominfect mthemhost mc
ell
B) doesmnot mappearmonmthemsurfacemof mCD4mTmcells
C) appearsmonmthemsurfacemof mthemCD4mTmcellsmand minactivatesmthemvirionmuponmbinding
D) interferesmwithmbindingmof mthemvirionmtomthemCD4mreceptormprotein
E) appearsmonmthemsurfacemof mthemCD4mTmcellsmand mcausesmthemvirionmtomlysemuponmbindi
ngmAnswer:mB
Section:m1.3
Skill:mApplication/Analysis
10) Them∆32mallelemof mCCR5mismfound mat mthemhighest mfrequencyminmwhichmof mthemfollowi
ngmpopulations?
A) Africans
B) Japanese
C) NorthmAmericans
D) Europeans
E) SouthmAmericansmAnswer:mDmSection:m1.
3mSkill:mKnowledge/Comprehension
A+ Pagem3
, Created mBy:mAmSolutio
n
11) HIV-
1mismbelieved mtomhavembeenmtransmitted mtomhumansmfrommwhichmof mthemfollowingmorganism
s?
A) gorillas
B) sootymmangabeys
C) Africanmgreenmmonkeys
D) chimpanzees
E) baboonsmAnswer:mDmSection:m1.
4mSkill:mKnowledge/Comprehension
12) HIV-
1mGroupmMmismresponsiblemform95%mof mhumanminfections.mWhenmismit mestimated mthat mHIV-
1mGroupmMmwasmtransferred mtomhumans?
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer:mCmSection:m1.4
Skill:mKnowledge/Comprehension
13) Antibodiesmand mkillermTmcellsmrecognizemHIV mormHIV-
infected mcellsmbymbindingmtomshort mpiecesmof mviralmproteinsmdisplayed monmthemvirusmormtheminfected
host mcell.mThesemshort mpiecesmof mviralmproteinsmare mcalled
m .
A) coat mproteins
B) virosomes
C) proteosomes
D) epitopes
E) episomesmAnswer:mD
Section:m1.5
Skill:mKnowledge/Comprehension
14) Tetherinmismanmimportant mproteinmproduced mbymthemhost.mWhat mismthemfunctionmof mtetherin
A+ Pagem4
n
TEST BANK FOR Evolutionary Analysis 5th Edition b
m m m m m m m
y Herron Jon; Freeman Scott ISBN 9780321998378 Ch
m m m m m m m
apter 1-20 A+
m m
Chapterm1m AmCasemformEvolutionarymThinking:mUnderstandingmHIV
1) Inmwhichmof mthemfollowingmregionsmhasmAIDSmkilled mthemlargest mnumbermof mindividuals?
A) India
B) Sub-SaharanmAfrica
C) United mStates
D) China
E) United mKingdommAnswer:mBmSection:m1.
1mSkill:mKnowledge/Comprehension
2) ThemHIV mvirusmcontainsmallmof mthemfollowingmcomponentsmexcept .
A) integrase
B) double-stranded mRNA
C) single-stranded mRNA
D) reversemtranscriptase
E) proteasemAnswer:mBmSection:m1.
1mSkill:mKnowledge/Comprehension
3) ThemacronymmHIV mstandsmformwhichmof mthemfollowing?
A) humanmintercellularmvirus
B) humanmimmunemvirus
C) humanmimmunodeficiencymvirus
D) humanmimmunitymvirus
E) humanmimmunodeficiencymvectormAnswer:m
CmSection:m1.1
Skill:mKnowledge/Comprehension
4) Whichmof mthemfollowingmenzymesmismresponsiblemformtranscribingmviralmRNA mintomDNA?
A+ Pagem1
,Created mBy:mAmSolutio
n
A) RNA mpolymerase
B) reversemtranscriptase
C) DNA mpolymerase
D) reversemintegrase
E) RNA mduplicasemAnswer:mBmSection:m1.
1mSkill:mKnowledge/Comprehension
5) Themproteinsmthat menablemthemHIV mvirusmtombind mtomcellsmaremtypicallymCD4mand mCCR5.m
Onmwhat mtypemof mcellsmaremthesemproteinsmtypicallymobserved?
A) plasmamcells
B) dendriticmcells
C) effectormhelpermTmcells
D) memorymhelpermTmcells
E) bothmCmand mD mAnswer:mEmSection:m1.
1mSkill:mKnowledge/Comprehension
6) ThemAIDSmphasemof mHIV minfectionmbeginsmwhenmthemconcentrationmof mCD4mTmcellsminmt
hemblood mdropsmbelow mwhat mconcentration?
A) 2,000mcellsmpermcubicmmillimeter
B) 1,000mcellsmpermcubicmmillimeter
C) 500mcellsmpermcubicmmillimeter
D) 200mcellsmpermcubicmmillimeter
E) NomCD4mTmcellsmaremobserved.mAnswer:m
DmSection:m1.1
Skill:mKnowledge/Comprehension
7) Whichmof mthemfollowingmdrugmcategoriesmaremused mtomtreat mHIV minfections?
A) integraseminhibitors
B) proteaseminhibitors
C) reversemtranscriptaseminhibitors
D) DNAseminhibitors
A+ Pagem2
,Created mBy:mAmSolutio
n
E) fusionminhibitorsmAnswer:mDmSection:m1.
2mSkill:mKnowledge/Comprehension
8) CoreceptorminhibitorsmblockmHIV minfectionmbympreventingmwhichmof mthemfollowing?
A) bindingmof mthemHIV mvirionmontomthemplasmammembrane
B) bindingmof mthemHIV mvirionmontomthemCCR5mreceptor
C) bindingmof mthemHIV mvirionmontomthemgp120mprotein
D) degradingmthemcoreceptormsomthemvirionmcannot mattach
E) bindingmof mthemHIV mvirionmontomthemCD4mreceptormAnswer:m
BmSection:m1.2
Skill:mApplication/Analysis
9) What mismthemeffect mof mthem∆32mallelemof mCCR5monmHIV mbinding?
A) appearsmonmthemsurfacemof mCD4mTmcells,mbut mthemHIV mvirionmismunablemtominfect mthemhost mc
ell
B) doesmnot mappearmonmthemsurfacemof mCD4mTmcells
C) appearsmonmthemsurfacemof mthemCD4mTmcellsmand minactivatesmthemvirionmuponmbinding
D) interferesmwithmbindingmof mthemvirionmtomthemCD4mreceptormprotein
E) appearsmonmthemsurfacemof mthemCD4mTmcellsmand mcausesmthemvirionmtomlysemuponmbindi
ngmAnswer:mB
Section:m1.3
Skill:mApplication/Analysis
10) Them∆32mallelemof mCCR5mismfound mat mthemhighest mfrequencyminmwhichmof mthemfollowi
ngmpopulations?
A) Africans
B) Japanese
C) NorthmAmericans
D) Europeans
E) SouthmAmericansmAnswer:mDmSection:m1.
3mSkill:mKnowledge/Comprehension
A+ Pagem3
, Created mBy:mAmSolutio
n
11) HIV-
1mismbelieved mtomhavembeenmtransmitted mtomhumansmfrommwhichmof mthemfollowingmorganism
s?
A) gorillas
B) sootymmangabeys
C) Africanmgreenmmonkeys
D) chimpanzees
E) baboonsmAnswer:mDmSection:m1.
4mSkill:mKnowledge/Comprehension
12) HIV-
1mGroupmMmismresponsiblemform95%mof mhumanminfections.mWhenmismit mestimated mthat mHIV-
1mGroupmMmwasmtransferred mtomhumans?
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer:mCmSection:m1.4
Skill:mKnowledge/Comprehension
13) Antibodiesmand mkillermTmcellsmrecognizemHIV mormHIV-
infected mcellsmbymbindingmtomshort mpiecesmof mviralmproteinsmdisplayed monmthemvirusmormtheminfected
host mcell.mThesemshort mpiecesmof mviralmproteinsmare mcalled
m .
A) coat mproteins
B) virosomes
C) proteosomes
D) epitopes
E) episomesmAnswer:mD
Section:m1.5
Skill:mKnowledge/Comprehension
14) Tetherinmismanmimportant mproteinmproduced mbymthemhost.mWhat mismthemfunctionmof mtetherin
A+ Pagem4
