1 of 92
Term
A 7-year-old boy arrives at the emergency department asleep in his
father's arms. The boy's mother explains that the boy spent the night
throwing up and experiencing severe diarrhea. History indicates the
boy became ill at dinnertime yesterday after spending time playing in
the basement. The mother reports that an exterminator had recently
take care of a rat problem in the basement and had used a poison
(Rotenone) that blocks complex I in the respiratory chain of oxidative
,phosphorylation. This will increase levels of NADH and would likely
impair function of which of the following enzymes?
Give this one a try later!
Pyruvate dehydrogenase
Pyruvate carboxylase
complex
Pyruvate kinase Succinate dehydrogenase
Don't know?
2 of 92
Term
ATP is a high energy molecule that is often hydrolyzed during
reactions. The energy within ATP is stored primarily in which of the
following components of the molecule?
Give this one a try later!
In the sugar ribose component of the In the overall molecular structure of
molecule adp
In the high energy phosphate
In the nitrogenous base adenine
bonds
, Don't know?
3 of 92
Term
UDP-glucose is required for glycogen synthesis and which of the
following pathways?
Give this one a try later!
Galactose metabolism
The conversion of galactose 1-phosphate to glucose 1-phosphate requires the
enzyme galactose-1-phosphate uridyl transferase. This reaction is an
exchange between galactose 1-phosphate and UDP-glucose to generate
glucose 1-phosphate and UDP-galactose.
Gluconeogenesis
Glucagon is secreted from α-cells in the pancreas in the fasted state. It primarily
activates fasted state pathways while directly or indirectly inhibiting fed state
pathways. Gluconeogenesis is the only fasted state pathway on this list.
Activation of chymotrypsinogen to chymotrypsin.
Synthesis of enzymes as proenzymes is positive in the case of digestive enzymes
such as chymotrypsin. This enzyme will only be active when cleaved under the
required circumstances.
, Glucose 6-phosphate dehydrogenase
Glucose 6-phosphate dehydrogenase is the regulatory enzyme of the pentose
phosphate pathway and is part of the oxidative part of the pathway. It is inhibited by
high levels of NADPH.
Don't know?
4 of 92
Term
A newborn is determined to have hyperinsulinemia. Which of the
following is likely to occur as a result of this deficiency?
Give this one a try later!
Increased activity of pyruvate
Increased glucose uptake by tissues
kinase
Decreased glycogen synthesis Decreased insulin secretion
Don't know?
5 of 92
Term
Term
A 7-year-old boy arrives at the emergency department asleep in his
father's arms. The boy's mother explains that the boy spent the night
throwing up and experiencing severe diarrhea. History indicates the
boy became ill at dinnertime yesterday after spending time playing in
the basement. The mother reports that an exterminator had recently
take care of a rat problem in the basement and had used a poison
(Rotenone) that blocks complex I in the respiratory chain of oxidative
,phosphorylation. This will increase levels of NADH and would likely
impair function of which of the following enzymes?
Give this one a try later!
Pyruvate dehydrogenase
Pyruvate carboxylase
complex
Pyruvate kinase Succinate dehydrogenase
Don't know?
2 of 92
Term
ATP is a high energy molecule that is often hydrolyzed during
reactions. The energy within ATP is stored primarily in which of the
following components of the molecule?
Give this one a try later!
In the sugar ribose component of the In the overall molecular structure of
molecule adp
In the high energy phosphate
In the nitrogenous base adenine
bonds
, Don't know?
3 of 92
Term
UDP-glucose is required for glycogen synthesis and which of the
following pathways?
Give this one a try later!
Galactose metabolism
The conversion of galactose 1-phosphate to glucose 1-phosphate requires the
enzyme galactose-1-phosphate uridyl transferase. This reaction is an
exchange between galactose 1-phosphate and UDP-glucose to generate
glucose 1-phosphate and UDP-galactose.
Gluconeogenesis
Glucagon is secreted from α-cells in the pancreas in the fasted state. It primarily
activates fasted state pathways while directly or indirectly inhibiting fed state
pathways. Gluconeogenesis is the only fasted state pathway on this list.
Activation of chymotrypsinogen to chymotrypsin.
Synthesis of enzymes as proenzymes is positive in the case of digestive enzymes
such as chymotrypsin. This enzyme will only be active when cleaved under the
required circumstances.
, Glucose 6-phosphate dehydrogenase
Glucose 6-phosphate dehydrogenase is the regulatory enzyme of the pentose
phosphate pathway and is part of the oxidative part of the pathway. It is inhibited by
high levels of NADPH.
Don't know?
4 of 92
Term
A newborn is determined to have hyperinsulinemia. Which of the
following is likely to occur as a result of this deficiency?
Give this one a try later!
Increased activity of pyruvate
Increased glucose uptake by tissues
kinase
Decreased glycogen synthesis Decreased insulin secretion
Don't know?
5 of 92
Term
