2025/l 2026l Update)l Essentiall Biologyl IIl
W/Labl |l Questionsl &l Answers|l Gradel A|l
100%l Correctl (Verifiedl Solutions)-l
Portagel Learning
Q:l Whichl ofl thel followingl statementsl isl truel regardingl thel blood-brainl barrierl (BBB)?
a.l Itl isl al semipermeable,l highlyl selectivel borderl comprisedl ofl bloodl vesselsl andl gliall
cells
b.l Antianxietyl drugsl canl passl throughl thel BBB.
c.l Anticancerl drugsl canl passl throughl thel BBB.
d.l d.l Antibioticsl canl passl throughl thel BBB.
e.l a.l andl b.l arel true.
f.l c.l andl d.l arel true.
Answer:
e
Q:l Newl Drugl Approvall Phase
Answer:
Al formall reviewl processl conductedl byl al specializedl branchl ofl thel FDA
Q:l Post-Marketingl Phase
Answer:
Adversel sidel effectsl continuel tol bel monitoredl duringl thisl phase,l andl al drugl mayl bel
removedl ifl newl risksl beginl tol appearl withinl thel generall population
,Q:l Preclinicall phase
Answer:
Itl involvesl exhaustivel laboratoryl workl thatl lastsl inl thel rangel ofl 1-3l years
Q:l Clinicall investigationl phase
Answer:
Clinicall trialsl occurl duringl thisl phase
Q:l Duringl whichl portionl ofl al clinicall trial,l dol participantsl signl informedl consentl
documents?
Answer:
Informedl consentl isl signedl duringl thel selectionl process.
Q:l Al drugl isl al ______l andl mayl actl asl anl ______,l inl whichl itl bindsl tol al receptorl
andl facilitatesl al cellularl response.
Answer:
ligand;l agonist
Q:l Whatl isl thel mechanisml ofl actionl ofl vasodilators?
Answer:
Dilatingl peripherall bloodl vessels
,Q:l Whichl ofl thel followingl studyl typesl reducesl selectionl bias?l (Selectl alll thatl apply)
Answer:
Double-blindl study
Q:l Whichl drugl safetyl categoryl posesl thel lowestl riskl tol thel developingl fetus?
Answer:
Categoryl A
Q:l Whyl mustl providersl takel thel firstl passl effectl intol considerationl whenl prescribingl
al specificl dosagel ofl al drug?
Answer:
Thel firstl passl effectl isl anl importantl considerationl forl drugl dosing;l drugl developersl
needl tol ensurel thatl thel drugl willl stilll bel effectivel afterl makingl thel initiall passl throughl
thel liver.
Q:l Thel disciplinel ofl sciencel thatl isl concernedl withl thel treatmentl ofl diseasel andl
sufferingl isl knownl asl ________
Answer:
Therapeutics
Q:l Whatl isl dependency?
, Answer:
Dependencyl isl al psychologicall (mental)l and/orl physiologicall (physical)l needl forl al
substance
Q:l Inl whichl phasel ofl al clinicall triall isl thel maximuml toleratedl dosel determined?
Answer:
Phasel 1
Q:l Inl thisl phasel ofl thel drugl developmentl process,l cellsl arel grownl inl culture,l andl
thel candidatel drugl isl testedl tol lookl forl potentiall harms.
Answer:
Preclinicall Phase
Q:l Internall validityl ensuresl thatl thel studyl resultsl arel generalizablel froml thel studyl
populationl tol thel broaderl generall population.
Answer:
False,l externall validityl ensuresl thatl thel studyl resultsl arel generalizablel froml thel studyl
populationl tol thel broaderl generall population.ORInternall validityl refersl tol thel adequatel
randomizationl ofl participantsl sol thatl biasesl arel removed,l andl accuratel cause-and-effectl
relationshipsl canl bel evaluated.
Q:l Whatl isl thel therapeuticl usefulnessl ofl antibiotics?
Answer:
Microorganisms