Nursing Pharmacology: Open Rn (2025)
All Chapters 1-40| 6 Units| Latest 2025 Edition With Verified And Detailed Answers| Rated A+
From: [Bestmaxsolutions.stuvia
,UNIT 1: GENERAL PRINCIPLES OF PHARMACOLOGY -------------------------------------------------------- 4
Chapter 01: PHARMACOKINETICS----------------------------------------------------------------------------------------4
Chapter 02: Pharmacodynamics---------------------------------------------------------------------------------------- 20
UNITS 2: AGENTS, CONTROLLING THE FUNCTIONS OF THE PERIPHERAL NERVOUS SYSTEM--- 35
Chapter 03: Local Anesthetics------------------------------------------------------------------------------------------- 35
Chapter 04: Cholinomimetic Drugs ------------------------------------------------------------------------------------ 51
Chapter 05: Cholinoreceptor Blocking Drugs ----------------------------------------------------------------------- 63
Chapter 06: Adrenoreceptor Activating Drugs---------------------------------------------------------------------- 92
UNIT 3: AGENTS, CONTROLLING THE FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM ------ 136
Chapter 07: Hypnotic Drugs------------------------------------------------------------------------------------------- 136
Chapter 08: Antiseizure Drugs ---------------------------------------------------------------------------------------- 154
Chapter 09: Antiparkinsonian Agents ------------------------------------------------------------------------------- 170
Chapter 10: Ethyl Alcohol ---------------------------------------------------------------------------------------------- 183
Chapter 11: Narcotic Analgesics -------------------------------------------------------------------------------------- 191
Chapter 12: Non-Narcotic Analgesics ------------------------------------------------------------------------------- 208
Chapter 13: Antipsychotic Agents------------------------------------------------------------------------------------ 217
Chapter 14: Antidepressant Agents --------------------------------------------------------------------------------- 233
Chapter 15: Anxiolytic Agents ---------------------------------------------------------------------------------------- 249
Chapter 16: CNS Stimulants ------------------------------------------------------------------------------------------- 260
Chapter 17: Drugs Of Abuse ------------------------------------------------------------------------------------------ 273
Chapter 18: General Anesthetics ------------------------------------------------------------------------------------- 284
UNIT 4: ORGANOTROPIC AGENTS---------------------------------------------------------------------------- 295
Chapter 19: Drugs Acting On Respiratory System --------------------------------------------------------------- 295
Chapter 20: Drugs Used In Gastrointestinal Diseases ----------------------------------------------------------- 304
Chapter 21: Drugs Acting On Hematopoietic System ----------------------------------------------------------- 316
Chapter 22: Drugs Used In Disorders Of Coagulation ----------------------------------------------------------- 322
Chapter 22: Drugs Used For Treatment Of Heart Failure ------------------------------------------------------ 330
Chapter 23: Antiarrhythmic Agents --------------------------------------------------------------------------------- 341
Chapter 25: Drugs For Angina Pectoris Treatment -------------------------------------------------------------- 350
Chapter 26: Antihypertensive Drugs -------------------------------------------------------------------------------- 362
Chapter 27: Hypertensive (Anti-Hypotensive) Drugs. Drugs Influencing Cerebral Blood Flow. Anti-
Migraine Agents ---------------------------------------------------------------------------------------------------------- 373
,UNIT 5: METABOLIC PROFILE DRUGS ----------------------------------------------------------------------- 384
Chapter 28: Hypothalamic & Pituitary Hormones, Thyroid & Antithyroid Drugs ------------------------ 384
Chapter 29: Pancreatic Hormones & Antidiabetic Drugs ------------------------------------------------------ 397
Chapter 30: The Gonadal Hormones & Inhibitors --------------------------------------------------------------- 407
Chapter 31: Glucocorticoid, Steroidal & Nonsteroidal Anti-Inflammatory Drugs ----------------------- 415
Chapter 32: Immunotropic & Antiallergic Agents---------------------------------------------------------------- 431
Chapter 33: Vitamins, Vitamin-Like Compounds, Antivitamins, Enzymes & Antienzymes ------------ 453
Chapter 34: Antihyperlipidemic Drugs & Drugs Used In The Treatment Of Gout ----------------------- 479
Chapter 35: Agents That Affect Bone Mineral Homeostasis -------------------------------------------------- 503
Chapter 36: Mineralocorticoid, Mineralocorticoid Antagonists, Diuretics, Plasma Expanders ------ 527
UNIT 6: CHEMOTHERAPEUTIC DRUGS ---------------------------------------------------------------------- 545
Chapter 37: Antibiotics ------------------------------------------------------------------------------------------------- 545
Chapter 38: Synthetic Antibacterial Drugs ------------------------------------------------------------------------- 571
Chapter 39: Antiprotozoal And Anthelmintic Drugs ------------------------------------------------------------ 591
Chapter 40: Antiviral Agents. Agents For Chemotherapy Of Cancer ---------------------------------------- 609
,UNIT 1: GENERAL PRINCIPLES OF PHARMACOLOGY
Chapter 01: PHARMACOKINETICS
Nursing Pharmacology: Open RN (2025) Test Bank
MULTIPLE CHOICE
01. Pharmacokinetics Is:
A) The Study Of Biological And Therapeutic Effects Of Drugs
B) The Study Of Absorption, Distribution, Metabolism And Excretion Of Drugs ✅
C) The Study Of Mechanisms Of Drug Action
D) The Study Of Methods Of New Drug Development
ANS: B
FeedBack: Pharmacokinetics Describes How The Body Affects A Drug Through The
Processes Of Absorption, Distribution, Metabolism, And Excretion (ADME). It's A Key
Aspect Of Understanding How A Drug Travels Through The Body And Influences
Dosing And Effectiveness.
02. What Does “Pharmacokinetics” Include?
A) Complications Of Drug Therapy
B) Drug Biotransformation In The Organism ✅
C) Influence Of Drugs On Metabolism Processes
D) Influence Of Drugs On Genes
ANS: B
FeedBack: Biotransformation (Metabolism) Is A Core Element Of Pharmacokinetics. It
Involves The Chemical Modification Of The Drug By The Body, Usually By Liver
Enzymes.
03. What Does “Pharmacokinetics” Include?
A) Pharmacological Effects Of Drugs
,B) Unwanted Effects Of Drugs
C) Chemical Structure Of A Medicinal Agent
D) Distribution Of Drugs In The Organism ✅
ANS: D
FeedBack: Distribution Is One Of The Four Key Components Of Pharmacokinetics,
Referring To The Movement Of A Drug From The Bloodstream Into Tissues And
Organs.
04. What Does “Pharmacokinetics” Include?
A) Localization Of Drug Action
B) Mechanisms Of Drug Action
C) Excretion Of Substances ✅
D) Interaction Of Substances
ANS: C
FeedBack: Excretion Is The Final Phase Of Pharmacokinetics And Involves The
Elimination Of Drugs From The Body, Primarily Through The Kidneys.
05. The Main Mechanism Of Most Drugs Absorption In GI Tract Is:
A) Active Transport (Carrier-Mediated Diffusion)
B) Filtration (Aqueous Diffusion)
C) Endocytosis And Exocytosis
D) Passive Diffusion (Lipid Diffusion) ✅
ANS: D
FeedBack: Most Drugs Are Absorbed Via Passive Diffusion, Especially If They Are
Lipid-Soluble And Non-Ionized, As They Can Easily Cross Cell Membranes.
06. What Kind Of Substances Can’t Permeate Membranes By Passive Diffusion?
A) Lipid-Soluble
,B) Non-Ionized Substances
C) Hydrophobic Substances
D) Hydrophilic Substances ✅
ANS: D
FeedBack: Hydrophilic (Water-Soluble) Substances Cannot Easily Cross The Lipid
Bilayer Of Cell Membranes Via Passive Diffusion And Often Require Channels Or
Transport Proteins.
07. A Hydrophilic Medicinal Agent Has The Following Property:
A) Low Ability To Penetrate Through The Cell Membrane Lipids ✅
B) Penetrate Through Membranes By Means Of Endocytosis
C) Easy Permeation Through The Blood-Brain Barrier
D) High Reabsorption In Renal Tubules
ANS: A
FeedBack: Hydrophilic Drugs Do Not Easily Penetrate Lipid Membranes Due To Their
Polarity And Poor Lipid Solubility, Which Limits Passive Diffusion.
08. What Is Implied By «Active Transport»?
A) Transport Of Drugs Through A Membrane By Means Of Diffusion
B) Transport Without Energy Consumption
C) Engulf Of Drug By A Cell Membrane With A New Vesicle Formation
D) Transport Against Concentration Gradient ✅
ANS: D
FeedBack: Active Transport Involves The Use Of Energy (ATP) To Move Substances
Against Their Concentration Gradient, Often With The Help Of Carrier Proteins.
09. What Does The Term “Bioavailability” Mean?
A) Plasma Protein Binding Degree Of Substance
,B) Permeability Through The Brain-Blood Barrier
C) Fraction Of An Uncharged Drug Reaching The Systemic Circulation Following Any
Route Administration ✅
D) Amount Of A Substance In Urine Relative To The Initial Dose
ANS: C
FeedBack: Bioavailability Measures The Extent And Rate At Which The Active Drug
Enters Systemic Circulation, Especially Important For Non-Intravenous Routes Like Oral
Administration.
10. The Reasons Determining Bioavailability Are:
A) Rheological Parameters Of Blood
B) Amount Of A Substance Obtained Orally And Quantity Of Intakes
C) Extent Of Absorption And Hepatic First-Pass Effect ✅
D) Glomerular Filtration Rate
ANS: C
FeedBack: Bioavailability Is Primarily Affected By How Well A Drug Is Absorbed And
How Much Of It Is Metabolized By The Liver Before Reaching Systemic Circulation,
Known As The First-Pass Effect.
11. Pick Out The Appropriate Alimentary Route Of Administration When Passage
Of Drugs Through Liver Is Minimized:
A) Oral
B) Transdermal
C) Rectal ✅
D) Intraduodenal
ANS: C
,FeedBack: Rectal Administration Partially Bypasses The Liver, Especially When The
Drug Is Absorbed By The Lower Rectum, Which Drains Directly Into The Systemic
Circulation, Reducing The First-Pass Effect.
12. Which Route Of Drug Administration Is Most Likely To Lead To The First-Pass
Effect?
A) Sublingual
B) Oral ✅
C) Intravenous
D) Intramuscular
ANS: B
FeedBack: Oral Drugs Pass Through The Gastrointestinal Tract And Enter The Portal
Circulation, Where They Are Metabolized By The Liver Before Reaching Systemic
Circulation. This Is Known As The First-Pass Effect, Which Can Significantly Reduce
Drug Bioavailability.
13. What Is Characteristic Of The Oral Route?
A) Fast Onset Of Effect
B) Absorption Depends On GI Tract Secretion And Motor Function ✅
C) A Drug Reaches The Blood Passing The Liver
D) The Sterilization Of Medicinal Forms Is Obligatory
ANS: B
FeedBack: Oral Drug Absorption Is Influenced By Several Gastrointestinal Factors Such
As Ph, Enzymes, Motility, And Presence Of Food. These Can Affect The Rate And
Extent Of Absorption.
14. Tick The Feature Of The Sublingual Route:
A) Pretty Fast Absorption ✅
B) A Drug Is Exposed To Gastric Secretion
,C) A Drug Is Exposed To More Prominent Liver Metabolism
D) A Drug Can Be Administered In A Variety Of Doses
ANS: A
FeedBack: Sublingual Administration Allows The Drug To Be Absorbed Directly Into
The Systemic Circulation Through The Mucosa Under The Tongue, Bypassing The
Liver, Leading To Faster Onset.
15. Pick Out The Parenteral Route Of Medicinal Agent Administration:
A) Rectal
B) Oral
C) Sublingual
D) Inhalation ✅
ANS: D
FeedBack: Parenteral Routes Bypass The Gastrointestinal Tract. While "Inhalation" Isn't
Traditionally Grouped With Injections (Like IV, IM), It Is Considered Parenteral Because
It Doesn't Involve The Digestive Tract And Allows Rapid Systemic Absorption.
16. Parenteral Administration:
A) Cannot Be Used With Unconscious Patients
B) Generally Results In A Less Accurate Dosage Than Oral Administration
C) Usually Produces A More Rapid Response Than Oral Administration ✅
D) Is Too Slow For Emergency Use
ANS: C
FeedBack: Parenteral Routes Such As IV Or IM Allow Rapid Onset, Especially
Important In Emergencies, And Can Be Used In Unconscious Or Vomiting Patients.
17. What Is Characteristic Of The Intramuscular Route Of Drug Administration?
A) Only Water Solutions Can Be Injected
, B) Oily Solutions Can Be Injected ✅
C) Opportunity Of Hypertonic Solution Injections
D) The Action Develops Slower Than Oral Administration
ANS: B
FeedBack: Intramuscular Injections Can Accept Both Aqueous And Oily Preparations,
Making Them Versatile. Oily Solutions Allow Slow And Sustained Drug Release.
18. Intravenous Injections Are More Suitable For Oily Solutions:
A) True
B) False ✅
ANS: B
FeedBack: Oily Solutions Should Not Be Administered Intravenously Because They Can
Cause Embolism Or Occlusion Of Blood Vessels. IV Administration Is Limited To
Aqueous Solutions.
19. Correct Statements Listing Characteristics Of A Particular Route Of Drug
Administration Include All Of The Following EXCEPT:
A) Intravenous Administration Provides A Rapid Response
B) Intramuscular Administration Requires A Sterile Technique
C) Inhalation Provides Slow Access To The General Circulation ❌
D) Subcutaneous Administration May Cause Local Irritation
ANS: C
FeedBack: Inhalation Offers Very Rapid Drug Absorption, Especially For Gases And
Volatile Substances, Due To The Large Surface Area Of The Lungs And Rich Blood
Supply.
20. Most Of Drugs Are Distributed Homogeneously.
A) True