Test Bank Complete_
Rang & Dale's Pharmacology 9th Edition,
By James M. Ritter Dphil, Rod J. Flower, Graeme Henderson, Yoon Kong Loke, David
Macewan & Humphrey P. Rang
All Chapters 1-60| 6 Units| Latest Edition With Verified Answers| Grade A+
From: [Bestmaxsolutions.Stuvia
,SECTION 1. GENERAL PRINCIPLES -------------------------------------------------------------------------------- 5
Chapter 1: What Is Pharmacology? --------------------------------------------------------------------------------------5
Chapter 2: How Drugs Act: General Principles ---------------------------------------------------------------------- 10
Chapter 3: How Drugs Act: Molecular Aspects --------------------------------------------------------------------- 15
Chapter 4: How Drugs Act: Cellular Aspects—Excitation, Contraction And Secretion ------------------- 24
Chapter 5. Biopharmaceuticals And Gene Therapy --------------------------------------------------------------- 31
Chapter 6: Cell Proliferation, Apoptosis, Repair And Regeneration ------------------------------------------ 39
Chapter 7. Cellular Mechanisms: Host Defence -------------------------------------------------------------------- 46
Chapter 8: Method And Measurement In Pharmacology-------------------------------------------------------- 52
Chapter 9: Absorption and distribution of drugs ------------------------------------------------------------------ 56
Chapter 10: Drug Metabolism And Elimination -------------------------------------------------------------------- 61
Chapter 11: Pharmacokinetics ------------------------------------------------------------------------------------------ 65
Chapter 12: Individual Variation, Pharmacogenomics and Personalised Medicine ----------------------- 69
SECTION 2. CHEMICAL MEDIATORS --------------------------------------------------------------------------- 72
Chapter 13: Chemical Mediators And The Autonomic Nervous System ------------------------------------- 72
Chapter 14: Cholinergic Transmission -------------------------------------------------------------------------------- 76
Chapter 15: Noradrenergic Transmission ---------------------------------------------------------------------------- 82
Chapter 16: 5-Hydroxytryptamine And The Pharmacology Of Migraine ------------------------------------ 87
Chapter 17. Purines -------------------------------------------------------------------------------------------------------- 90
Chapter 18. Local Hormones 1: Histamin And The Biologically Active Lipids. ------------------------------ 96
Chapter 19. Local Hormones 2: Peptides And Proteins--------------------------------------------------------- 101
Chapter 20: Cannabinoids---------------------------------------------------------------------------------------------- 103
Chapter 21: Nitric Oxide And Other Gaseous Mediators ------------------------------------------------------ 105
SECTION 3. DRUGS AFFECTING MAJOR ORGAN SYSTEMS --------------------------------------------- 108
Chapter 22: The Heart--------------------------------------------------------------------------------------------------- 108
Chapter 23: The Vascular System ------------------------------------------------------------------------------------ 113
Chapter 24: Atherosclerosis And Lipid Metabolism ------------------------------------------------------------- 118
Chapter 25: Haemostasis And Thrombosis ------------------------------------------------------------------------ 121
Chapter 26: Haemopoietic System----------------------------------------------------------------------------------- 125
Chapter 27: Anti-Inflammatory And Immunosuppressant Drugs -------------------------------------------- 128
Chapter 28. Skin ---------------------------------------------------------------------------------------------------------- 133
, Chapter 29: Respiratory System -------------------------------------------------------------------------------------- 139
Chapter 30: The Kidney And Urinary System --------------------------------------------------------------------- 142
Chapter 31: The Gastrointestinal Tract ----------------------------------------------------------------------------- 146
Chapter 32: The Control Of Blood Glucose And Drug Treatment Of Diabetes Mellitus ---------------- 149
Chapter 33: Obesity ----------------------------------------------------------------------------------------------------- 152
Chapter 34: The Pituitary And The Adrenal Cortex -------------------------------------------------------------- 154
Chapter 35: The Thyroid ------------------------------------------------------------------------------------------------ 157
Chapter 36: The Reproductive System ------------------------------------------------------------------------------ 160
Chapter 37: Bone Metabolism ---------------------------------------------------------------------------------------- 164
SECTION 4. NERVOUS SYSTEM -------------------------------------------------------------------------------- 167
Chapter 38: Chemical Transmission And Drug Action In The Central Nervous System ---------------- 167
Chapter 39: Amino Acid Transmitters ------------------------------------------------------------------------------ 169
Chapter 40: Other Transmitters And Modulators --------------------------------------------------------------- 172
Chapter 41: Neurodegenerative Diseases ------------------------------------------------------------------------- 175
Chapter 42: General Anaesthetic Agents -------------------------------------------------------------------------- 179
Chapter 43: Analgesic Drugs ------------------------------------------------------------------------------------------- 182
Chapter 44: Local Anaesthetics And Other Drugs Affecting Sodium Channels --------------------------- 187
Chapter 45: Anxiolytic And Hypnotic Drugs ----------------------------------------------------------------------- 189
Chapter 46: Antiepileptic Drugs -------------------------------------------------------------------------------------- 192
Chapter 47: Antipsychotic Drugs ------------------------------------------------------------------------------------- 195
Chapter 48: Antidepressant Drugs ----------------------------------------------------------------------------------- 198
Chapter 49: CNS Stimulants And Psychotomimetic Drugs ----------------------------------------------------- 203
Chapter 50: Drug Addiction, Dependence, And Abuse --------------------------------------------------------- 206
SECTION 5. DRUGS USED FOR THE TREATMENT OF INFECTIONS AND CANCER ------------------ 211
Chapter 51: Basic Principles Of Antimicrobial Chemotherapy ------------------------------------------------ 211
Chapter 52: Antibacterial Drugs -------------------------------------------------------------------------------------- 214
Chapter 53: Antiviral Drugs -------------------------------------------------------------------------------------------- 218
Chapter 54: Antifungal Drugs ----------------------------------------------------------------------------------------- 221
Chapter 55: Antiprotozoal Drugs ------------------------------------------------------------------------------------- 223
Chapter 56: Anthelminthic Drugs ------------------------------------------------------------------------------------ 226
Chapter 57: Anti-cancer Drugs ---------------------------------------------------------------------------------------- 228
,SECTION 6. SPECIAL TOPICS------------------------------------------------------------------------------------ 232
Chapter 58: Harmful Effects Of Drugs ------------------------------------------------------------------------------- 232
Chapter 59: Lifestyle Drugs And Drugs In Sport ------------------------------------------------------------------ 236
Chapter 60: Drug Discovery And Development ------------------------------------------------------------------ 237
,SECTION 1. GENERAL PRINCIPLES
Chapter 1: What Is Pharmacology?
James M. Ritter: Rang & Dale's Pharmacology 9th Edition, Test Bank
MULTIPLE CHOICE
1. What Is The Primary Focus Of Pharmacology?
A. The Study Of Disease Processes
B. The Study Of Drug Interactions With Living Systems
C. The Formulation Of Pharmaceutical Products
D. The Management Of Patient Care
ANSWER: B.
Pharmacology Is The Branch Of Science Concerned With The Study Of Drug Actions On
Biological Systems. It Encompasses Understanding How Drugs Interact With Biological
Systems To Affect Function, Including Mechanisms Of Action, Therapeutic Effects, And
Side Effects.
2. Which Of The Following Best Defines A 'Drug' In Pharmacology?
A. Any Substance Used In The Diagnosis, Cure, Mitigation, Treatment, Or
Prevention Of Disease
B. Only Synthetic Substances Designed In Laboratories
C. Natural Substances With No Therapeutic Use
D. Substances That Alter The Structure Of DNA
ANSWER: A.
,In Pharmacology, A Drug Is Defined As Any Chemical Substance That, When
Administered To A Living Organism, Produces A Biological Effect. This Includes
Substances Used To Diagnose, Cure, Mitigate, Treat, Or Prevent Diseases.
3. What Are The Primary Targets Through Which Most Drugs Exert Their Effects?
A. DNA And RNA
B. Lipids And Carbohydrates
C. Proteins Such As Receptors, Enzymes, Ion Channels, And Transporters
D. Vitamins And Minerals
ANSWER: C.
Most Drugs Exert Their Effects By Interacting With Specific Proteins In The Body,
Including Receptors, Enzymes, Ion Channels, And Transporters. These Interactions Can
Modulate Physiological Processes, Leading To Therapeutic Effects.
4. Which Of The Following Statements About Receptors Is TRUE?
A. All Drugs Act Through Receptors
B. Receptors Are Only Found On The Cell Surface
C. Receptors Are Specific Protein Molecules That Drugs Bind To, Initiating A
Response
D. Receptors Are Non-Specific Binding Sites For All Chemicals
ANSWER: C.
Receptors Are Specific Proteins That Recognize And Bind To Particular Molecules
(Ligands), Such As Drugs, Leading To A Biological Response. They Can Be Located On
The Cell Surface Or Within Cells.
5. What Is The Term For The Study Of How The Body Affects A Drug Over Time?
A. Pharmacodynamics
B. Pharmacokinetics
C. Pharmacogenomics
, D. Toxicology
ANSWER: B.
Pharmacokinetics Involves The Study Of How The Body Absorbs, Distributes,
Metabolizes, And Excretes Drugs. It Describes The Time Course Of Drug Concentrations
In The Body.
6. Which Process Describes The Movement Of A Drug From Its Site Of Administration
Into The Bloodstream?
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
ANSWER: C.
Absorption Is The Process By Which A Drug Enters The Bloodstream From Its Site Of
Administration. The Rate And Extent Of Absorption Can Influence The Onset And
Intensity Of The Drug's Effect.
7. What Is The Main Focus Of Pharmacodynamics?
A. The Genetic Factors Influencing Drug Response
B. The Movement Of Drugs Within The Body
C. The Biochemical And Physiological Effects Of Drugs And Their Mechanisms Of
Action
D. The Economic Aspects Of Drug Therapy
ANSWER: C.
Pharmacodynamics Studies How Drugs Affect The Body, Including The Mechanisms By
Which Drugs Exert Their Effects, The Relationship Between Drug Concentration And
Effect, And The Drug's Therapeutic And Toxic Effects.
Rang & Dale's Pharmacology 9th Edition,
By James M. Ritter Dphil, Rod J. Flower, Graeme Henderson, Yoon Kong Loke, David
Macewan & Humphrey P. Rang
All Chapters 1-60| 6 Units| Latest Edition With Verified Answers| Grade A+
From: [Bestmaxsolutions.Stuvia
,SECTION 1. GENERAL PRINCIPLES -------------------------------------------------------------------------------- 5
Chapter 1: What Is Pharmacology? --------------------------------------------------------------------------------------5
Chapter 2: How Drugs Act: General Principles ---------------------------------------------------------------------- 10
Chapter 3: How Drugs Act: Molecular Aspects --------------------------------------------------------------------- 15
Chapter 4: How Drugs Act: Cellular Aspects—Excitation, Contraction And Secretion ------------------- 24
Chapter 5. Biopharmaceuticals And Gene Therapy --------------------------------------------------------------- 31
Chapter 6: Cell Proliferation, Apoptosis, Repair And Regeneration ------------------------------------------ 39
Chapter 7. Cellular Mechanisms: Host Defence -------------------------------------------------------------------- 46
Chapter 8: Method And Measurement In Pharmacology-------------------------------------------------------- 52
Chapter 9: Absorption and distribution of drugs ------------------------------------------------------------------ 56
Chapter 10: Drug Metabolism And Elimination -------------------------------------------------------------------- 61
Chapter 11: Pharmacokinetics ------------------------------------------------------------------------------------------ 65
Chapter 12: Individual Variation, Pharmacogenomics and Personalised Medicine ----------------------- 69
SECTION 2. CHEMICAL MEDIATORS --------------------------------------------------------------------------- 72
Chapter 13: Chemical Mediators And The Autonomic Nervous System ------------------------------------- 72
Chapter 14: Cholinergic Transmission -------------------------------------------------------------------------------- 76
Chapter 15: Noradrenergic Transmission ---------------------------------------------------------------------------- 82
Chapter 16: 5-Hydroxytryptamine And The Pharmacology Of Migraine ------------------------------------ 87
Chapter 17. Purines -------------------------------------------------------------------------------------------------------- 90
Chapter 18. Local Hormones 1: Histamin And The Biologically Active Lipids. ------------------------------ 96
Chapter 19. Local Hormones 2: Peptides And Proteins--------------------------------------------------------- 101
Chapter 20: Cannabinoids---------------------------------------------------------------------------------------------- 103
Chapter 21: Nitric Oxide And Other Gaseous Mediators ------------------------------------------------------ 105
SECTION 3. DRUGS AFFECTING MAJOR ORGAN SYSTEMS --------------------------------------------- 108
Chapter 22: The Heart--------------------------------------------------------------------------------------------------- 108
Chapter 23: The Vascular System ------------------------------------------------------------------------------------ 113
Chapter 24: Atherosclerosis And Lipid Metabolism ------------------------------------------------------------- 118
Chapter 25: Haemostasis And Thrombosis ------------------------------------------------------------------------ 121
Chapter 26: Haemopoietic System----------------------------------------------------------------------------------- 125
Chapter 27: Anti-Inflammatory And Immunosuppressant Drugs -------------------------------------------- 128
Chapter 28. Skin ---------------------------------------------------------------------------------------------------------- 133
, Chapter 29: Respiratory System -------------------------------------------------------------------------------------- 139
Chapter 30: The Kidney And Urinary System --------------------------------------------------------------------- 142
Chapter 31: The Gastrointestinal Tract ----------------------------------------------------------------------------- 146
Chapter 32: The Control Of Blood Glucose And Drug Treatment Of Diabetes Mellitus ---------------- 149
Chapter 33: Obesity ----------------------------------------------------------------------------------------------------- 152
Chapter 34: The Pituitary And The Adrenal Cortex -------------------------------------------------------------- 154
Chapter 35: The Thyroid ------------------------------------------------------------------------------------------------ 157
Chapter 36: The Reproductive System ------------------------------------------------------------------------------ 160
Chapter 37: Bone Metabolism ---------------------------------------------------------------------------------------- 164
SECTION 4. NERVOUS SYSTEM -------------------------------------------------------------------------------- 167
Chapter 38: Chemical Transmission And Drug Action In The Central Nervous System ---------------- 167
Chapter 39: Amino Acid Transmitters ------------------------------------------------------------------------------ 169
Chapter 40: Other Transmitters And Modulators --------------------------------------------------------------- 172
Chapter 41: Neurodegenerative Diseases ------------------------------------------------------------------------- 175
Chapter 42: General Anaesthetic Agents -------------------------------------------------------------------------- 179
Chapter 43: Analgesic Drugs ------------------------------------------------------------------------------------------- 182
Chapter 44: Local Anaesthetics And Other Drugs Affecting Sodium Channels --------------------------- 187
Chapter 45: Anxiolytic And Hypnotic Drugs ----------------------------------------------------------------------- 189
Chapter 46: Antiepileptic Drugs -------------------------------------------------------------------------------------- 192
Chapter 47: Antipsychotic Drugs ------------------------------------------------------------------------------------- 195
Chapter 48: Antidepressant Drugs ----------------------------------------------------------------------------------- 198
Chapter 49: CNS Stimulants And Psychotomimetic Drugs ----------------------------------------------------- 203
Chapter 50: Drug Addiction, Dependence, And Abuse --------------------------------------------------------- 206
SECTION 5. DRUGS USED FOR THE TREATMENT OF INFECTIONS AND CANCER ------------------ 211
Chapter 51: Basic Principles Of Antimicrobial Chemotherapy ------------------------------------------------ 211
Chapter 52: Antibacterial Drugs -------------------------------------------------------------------------------------- 214
Chapter 53: Antiviral Drugs -------------------------------------------------------------------------------------------- 218
Chapter 54: Antifungal Drugs ----------------------------------------------------------------------------------------- 221
Chapter 55: Antiprotozoal Drugs ------------------------------------------------------------------------------------- 223
Chapter 56: Anthelminthic Drugs ------------------------------------------------------------------------------------ 226
Chapter 57: Anti-cancer Drugs ---------------------------------------------------------------------------------------- 228
,SECTION 6. SPECIAL TOPICS------------------------------------------------------------------------------------ 232
Chapter 58: Harmful Effects Of Drugs ------------------------------------------------------------------------------- 232
Chapter 59: Lifestyle Drugs And Drugs In Sport ------------------------------------------------------------------ 236
Chapter 60: Drug Discovery And Development ------------------------------------------------------------------ 237
,SECTION 1. GENERAL PRINCIPLES
Chapter 1: What Is Pharmacology?
James M. Ritter: Rang & Dale's Pharmacology 9th Edition, Test Bank
MULTIPLE CHOICE
1. What Is The Primary Focus Of Pharmacology?
A. The Study Of Disease Processes
B. The Study Of Drug Interactions With Living Systems
C. The Formulation Of Pharmaceutical Products
D. The Management Of Patient Care
ANSWER: B.
Pharmacology Is The Branch Of Science Concerned With The Study Of Drug Actions On
Biological Systems. It Encompasses Understanding How Drugs Interact With Biological
Systems To Affect Function, Including Mechanisms Of Action, Therapeutic Effects, And
Side Effects.
2. Which Of The Following Best Defines A 'Drug' In Pharmacology?
A. Any Substance Used In The Diagnosis, Cure, Mitigation, Treatment, Or
Prevention Of Disease
B. Only Synthetic Substances Designed In Laboratories
C. Natural Substances With No Therapeutic Use
D. Substances That Alter The Structure Of DNA
ANSWER: A.
,In Pharmacology, A Drug Is Defined As Any Chemical Substance That, When
Administered To A Living Organism, Produces A Biological Effect. This Includes
Substances Used To Diagnose, Cure, Mitigate, Treat, Or Prevent Diseases.
3. What Are The Primary Targets Through Which Most Drugs Exert Their Effects?
A. DNA And RNA
B. Lipids And Carbohydrates
C. Proteins Such As Receptors, Enzymes, Ion Channels, And Transporters
D. Vitamins And Minerals
ANSWER: C.
Most Drugs Exert Their Effects By Interacting With Specific Proteins In The Body,
Including Receptors, Enzymes, Ion Channels, And Transporters. These Interactions Can
Modulate Physiological Processes, Leading To Therapeutic Effects.
4. Which Of The Following Statements About Receptors Is TRUE?
A. All Drugs Act Through Receptors
B. Receptors Are Only Found On The Cell Surface
C. Receptors Are Specific Protein Molecules That Drugs Bind To, Initiating A
Response
D. Receptors Are Non-Specific Binding Sites For All Chemicals
ANSWER: C.
Receptors Are Specific Proteins That Recognize And Bind To Particular Molecules
(Ligands), Such As Drugs, Leading To A Biological Response. They Can Be Located On
The Cell Surface Or Within Cells.
5. What Is The Term For The Study Of How The Body Affects A Drug Over Time?
A. Pharmacodynamics
B. Pharmacokinetics
C. Pharmacogenomics
, D. Toxicology
ANSWER: B.
Pharmacokinetics Involves The Study Of How The Body Absorbs, Distributes,
Metabolizes, And Excretes Drugs. It Describes The Time Course Of Drug Concentrations
In The Body.
6. Which Process Describes The Movement Of A Drug From Its Site Of Administration
Into The Bloodstream?
A. Distribution
B. Metabolism
C. Absorption
D. Excretion
ANSWER: C.
Absorption Is The Process By Which A Drug Enters The Bloodstream From Its Site Of
Administration. The Rate And Extent Of Absorption Can Influence The Onset And
Intensity Of The Drug's Effect.
7. What Is The Main Focus Of Pharmacodynamics?
A. The Genetic Factors Influencing Drug Response
B. The Movement Of Drugs Within The Body
C. The Biochemical And Physiological Effects Of Drugs And Their Mechanisms Of
Action
D. The Economic Aspects Of Drug Therapy
ANSWER: C.
Pharmacodynamics Studies How Drugs Affect The Body, Including The Mechanisms By
Which Drugs Exert Their Effects, The Relationship Between Drug Concentration And
Effect, And The Drug's Therapeutic And Toxic Effects.
