ANAEMIA
MABONGA C.W
MEDICAL PHYSIOLOGIST
, Anaemia is a reduction in the red cell mass or Hb
levels <12 g/dl in females and 13g/dl in males
(WHO).
Functionally it is a state in which the circulating red
cell mass is insufficient to meet the tissue oxygen
requirements.
Anaemia is not a diagnosis but a symptom that
requires further investigation to establish the
etiology.
Anaemia is twice as prevalent in females compared
to males with the difference greater in the
childbearing years.
,Classification of Anaemia
1. Etiological classification
a. Impaired production.
Iron deficiency anaemia
Folate and vitamin B12 deficiency
anaemia.
Thalassemias.
Aplastic anaemia.
PRCA
Anaemia due to renal failure.
, b. Increased red cell destruction.
Intrinsic
Enzyme disorders
Membrane disorders.
Hemoglobinopathies.
Extrinsic
Autoimmune
Transfusion reactions
Rhesus incompatibility.
Drug reactions
MABONGA C.W
MEDICAL PHYSIOLOGIST
, Anaemia is a reduction in the red cell mass or Hb
levels <12 g/dl in females and 13g/dl in males
(WHO).
Functionally it is a state in which the circulating red
cell mass is insufficient to meet the tissue oxygen
requirements.
Anaemia is not a diagnosis but a symptom that
requires further investigation to establish the
etiology.
Anaemia is twice as prevalent in females compared
to males with the difference greater in the
childbearing years.
,Classification of Anaemia
1. Etiological classification
a. Impaired production.
Iron deficiency anaemia
Folate and vitamin B12 deficiency
anaemia.
Thalassemias.
Aplastic anaemia.
PRCA
Anaemia due to renal failure.
, b. Increased red cell destruction.
Intrinsic
Enzyme disorders
Membrane disorders.
Hemoglobinopathies.
Extrinsic
Autoimmune
Transfusion reactions
Rhesus incompatibility.
Drug reactions
