ANCC Domain 1 Exam
Questions with Complete
Solutions
What direct-acting dopamine receptor agonist is recommended to be used in the treatment of
neuroleptic malignant syndrome (NMS) to help lower the dopamine receptor blockade?
A. Dantrolene (Dantrium)
B. Benztropine (Cogentin)
C. Bromocriptine (Parlodel)
D. Trihexyphenidyl (Artane) - Correct Answers: C. Bromocriptine (Parlodel)
A 74 y/o female present for an evaluation. The psychiatric nurse practitioner has the patient complete
the mini mental status examination and clock drawing. The patient is unable to correctly draw the face
of the clock. Which area of the brain is likely to have compromised functioning?
A. Corpus callosum
B. Wernicke's Area
C. Left Hemisphere
D. Right Hemisphere - Correct Answers: D. Right Hemisphere
Which of the following statements reflects current understanding of neurodevelopment and best
explains risk-taking behaviors of adolescent males?
A. Stimulant and substance use impairs judgment and cognitive appraisal
B. Pruning of serotonin circuits in the adolescent brain is associated with increased impulsivity
C. Maturation of the prefrontal cortex continues into mid-20s and early 30s
D. Hormonal flooding, especially testosterone and oxytocin, increase dopamine levels in the brain -
Correct Answers: C. Maturation of the prefrontal cortex continues into mid-20s and early 30s
What cytochrome (CYP) enzyme is implicated as a tobacco inducer when an individual is treated on
clozapine?
A. 2C19
, B. 1A2
C. 2C9
D. 2D6 - Correct Answers: B. 1A2
As a psychiatric mental health nurse practitioner, you are aware of antipsychotic medication side effects.
Which of the following side effects of antipsychotic medications has an insidious, delayed-onset typically
1 to 2 years after initiation of the medication?
A. Sedation
B. Weight gain
C. Tardive dyskinesia
D. Dry mouth - Correct Answers: C. Tardive dyskinesia
Which mood stabilizer is most associated with a potentially life-threatening rash?
A. Divalproex (depakote)
B. Carbamazepine (tegretol)
C. Lithium (eskalith)
D. Lamotrigine (lamictal) - Correct Answers: D. Lamotrigine (lamictal)
The psychiatric-Mental Health Nurse Practitioner would expect to see which of the following during a
physical exam for a patient with bulimia nervosa?
A. Alopecia areata
B. Tachycardia
C. Erosion of dental enamel
D. Obesity - Correct Answers: C. Erosion of dental enamel
Which of the following statements does not reflect current understanding of neurotransmitter pathways
implicated in anxiety disorders?
A. Decreasing norepinephrine in the locus ceruleus diminishes symptoms of anxiety
B. Increasing serotonergic activity in the amygdala diminishes symptoms of anxiety
Questions with Complete
Solutions
What direct-acting dopamine receptor agonist is recommended to be used in the treatment of
neuroleptic malignant syndrome (NMS) to help lower the dopamine receptor blockade?
A. Dantrolene (Dantrium)
B. Benztropine (Cogentin)
C. Bromocriptine (Parlodel)
D. Trihexyphenidyl (Artane) - Correct Answers: C. Bromocriptine (Parlodel)
A 74 y/o female present for an evaluation. The psychiatric nurse practitioner has the patient complete
the mini mental status examination and clock drawing. The patient is unable to correctly draw the face
of the clock. Which area of the brain is likely to have compromised functioning?
A. Corpus callosum
B. Wernicke's Area
C. Left Hemisphere
D. Right Hemisphere - Correct Answers: D. Right Hemisphere
Which of the following statements reflects current understanding of neurodevelopment and best
explains risk-taking behaviors of adolescent males?
A. Stimulant and substance use impairs judgment and cognitive appraisal
B. Pruning of serotonin circuits in the adolescent brain is associated with increased impulsivity
C. Maturation of the prefrontal cortex continues into mid-20s and early 30s
D. Hormonal flooding, especially testosterone and oxytocin, increase dopamine levels in the brain -
Correct Answers: C. Maturation of the prefrontal cortex continues into mid-20s and early 30s
What cytochrome (CYP) enzyme is implicated as a tobacco inducer when an individual is treated on
clozapine?
A. 2C19
, B. 1A2
C. 2C9
D. 2D6 - Correct Answers: B. 1A2
As a psychiatric mental health nurse practitioner, you are aware of antipsychotic medication side effects.
Which of the following side effects of antipsychotic medications has an insidious, delayed-onset typically
1 to 2 years after initiation of the medication?
A. Sedation
B. Weight gain
C. Tardive dyskinesia
D. Dry mouth - Correct Answers: C. Tardive dyskinesia
Which mood stabilizer is most associated with a potentially life-threatening rash?
A. Divalproex (depakote)
B. Carbamazepine (tegretol)
C. Lithium (eskalith)
D. Lamotrigine (lamictal) - Correct Answers: D. Lamotrigine (lamictal)
The psychiatric-Mental Health Nurse Practitioner would expect to see which of the following during a
physical exam for a patient with bulimia nervosa?
A. Alopecia areata
B. Tachycardia
C. Erosion of dental enamel
D. Obesity - Correct Answers: C. Erosion of dental enamel
Which of the following statements does not reflect current understanding of neurotransmitter pathways
implicated in anxiety disorders?
A. Decreasing norepinephrine in the locus ceruleus diminishes symptoms of anxiety
B. Increasing serotonergic activity in the amygdala diminishes symptoms of anxiety
