1
Nr 566 midterm review EXAM LATEST UPDATES -
2025/2026- ACTUAL QUESTIONS AND CORRECT
ANSWERS ALREADY GRADED A+ GUARANTEED
SUCCESS
How should we educate patient to take Phentermine/topiramate to avoid insomnia?
given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution?
hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects
insomnia, nervousness, anxiety, depression, blurred vision
What is the maximum recommended duration of use for non-amphetamines?
3 months or less
What drug schedule are Phentermine and Diethylpropion under?
Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for?
-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects
-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss?
Increases satiety
, 2
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%.
GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that
may not be absorbed well when taking Orlistat.
2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
12
Orlistat results in the least amount of weight loss of all. How much?
2-3% body weight (7 lbs in year)
Orlistat adverse effects
Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage
(light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated?
In those with malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially
if the patient is on coumadin?
Monitor Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
A patient with a BMI of 27 would be considered:
overweight
Lorcaserin adverse effects
headache, URI, back pain, hypoglycemia (in DM), blood dyscrasias, cognitive
impairment, psychiatric disorders, priapism, pulmonary hypertension, and valvular
heart disease
Lorcaserin MOA
Reduces waist circumference, fasting glucose, insulin, total cholesterol, LDL,
triglycerides
, 3
When is Lorcaserin contraindicated?
CrCl <30
-Not approved in children
Lorcaserin drug interactions
-MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning
increased risk for suicidal ideation and suicide attempts in children, adolescents,
and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____.
-two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what?
opioids
Naltrexone and Bupropion contraindications
HTN, seizure disorders, eating disorders, alcohol or drug withdrawal
Liraglutide MOA
-promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm
10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes
hypoglycemia
Baseline labs for Liraglutide
, 4
lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning
associated with a risk for thyroid C-cell tumors based on studies in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2
(MEN 2) or personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more
150
What BMI is bariatric surgery considered?
35 or more
Common procedures:
-Gastric Bypass Surgery (Roux-en-Y procedure)
-Laparoscopic implantation of an adjustable gastric band
What is typical weight loss for those who diligently adhere to medication and
lifestyle therapy?____% whereas >____% is exceptional
10-15%
> 15%
Most weight loss occurs during the first ___ months of treatment
6
T or F: Dosage adjustments are not indicated for orlistat, diethylpropion, and
phentermine in the elderly
T
Stage 0:
BMI ≥ 25 = lifestyle therapy -> consider drug therapy if lifestyle therapy is
ineffective to meet goals
Stage 1:
BMI of 25-26 = lifestyle therapy -> consider drug therapy if lifestyle therapy is
ineffective to meet goals
Nr 566 midterm review EXAM LATEST UPDATES -
2025/2026- ACTUAL QUESTIONS AND CORRECT
ANSWERS ALREADY GRADED A+ GUARANTEED
SUCCESS
How should we educate patient to take Phentermine/topiramate to avoid insomnia?
given before 1600
What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution?
hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects
insomnia, nervousness, anxiety, depression, blurred vision
What is the maximum recommended duration of use for non-amphetamines?
3 months or less
What drug schedule are Phentermine and Diethylpropion under?
Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for?
-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects
-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss?
Increases satiety
, 2
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%.
GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that
may not be absorbed well when taking Orlistat.
2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
12
Orlistat results in the least amount of weight loss of all. How much?
2-3% body weight (7 lbs in year)
Orlistat adverse effects
Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage
(light-colored stools, dark urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated?
In those with malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially
if the patient is on coumadin?
Monitor Coumadin as Vitamin K deficiency may occur and intensify effect of
Coumadin.
A patient with a BMI of 27 would be considered:
overweight
Lorcaserin adverse effects
headache, URI, back pain, hypoglycemia (in DM), blood dyscrasias, cognitive
impairment, psychiatric disorders, priapism, pulmonary hypertension, and valvular
heart disease
Lorcaserin MOA
Reduces waist circumference, fasting glucose, insulin, total cholesterol, LDL,
triglycerides
, 3
When is Lorcaserin contraindicated?
CrCl <30
-Not approved in children
Lorcaserin drug interactions
-MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning
increased risk for suicidal ideation and suicide attempts in children, adolescents,
and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____.
-two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what?
opioids
Naltrexone and Bupropion contraindications
HTN, seizure disorders, eating disorders, alcohol or drug withdrawal
Liraglutide MOA
-promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm
10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes
hypoglycemia
Baseline labs for Liraglutide
, 4
lipids, CMP, HgA1C q 6 months, triglycerides
Liraglutide black box warning
associated with a risk for thyroid C-cell tumors based on studies in rodents
-Contraindicated in people with multiple endocrine neoplasia syndrome type 2
(MEN 2) or personal/family history of medullary thyroid carcinoma
Those trying to LOSE weight should exercise at least ____ min/week or more
150
What BMI is bariatric surgery considered?
35 or more
Common procedures:
-Gastric Bypass Surgery (Roux-en-Y procedure)
-Laparoscopic implantation of an adjustable gastric band
What is typical weight loss for those who diligently adhere to medication and
lifestyle therapy?____% whereas >____% is exceptional
10-15%
> 15%
Most weight loss occurs during the first ___ months of treatment
6
T or F: Dosage adjustments are not indicated for orlistat, diethylpropion, and
phentermine in the elderly
T
Stage 0:
BMI ≥ 25 = lifestyle therapy -> consider drug therapy if lifestyle therapy is
ineffective to meet goals
Stage 1:
BMI of 25-26 = lifestyle therapy -> consider drug therapy if lifestyle therapy is
ineffective to meet goals
