NURS 615 exam 1 2025, Maryville University nursing exam
NURS 615 EXAM 1 2025, MARYVILLE UNIVERSITY NURSING EXAM
QUESTIONS, VERIFIED NURS 615 ANSWERS, NURS 615 STUDY GUIDE
PDF, NURS 615 EXAM PREP 2025, GRADED A+
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range - ANSWER-3. Onset of action
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
1. When the drug has a wide therapeutic range
2. When the drug will be administered for a short time only
3. When there is a high correlation between the dose and saturation of receptor sites
4. To determine if a drug is in the therapeutic range - ANSWER-4. To determine if a drug is in the
therapeutic range
A laboratory result indicates that the peak level for a drug is above the minimum toxic
concentration. This means that the:
1. Concentration will produce therapeutic effects
2. Concentration will produce an adverse response
3. Time between doses must be shortened
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, NURS 615 exam 1 2025, Maryville University nursing exam
4. Duration of action of the drug is too long - ANSWER-2. Concentration will produce an adverse
response
Drugs that are receptor agonists may demonstrate what property?
1. Irreversible binding to the drug receptor site
2. Upregulation with chronic use
3. Desensitization or downregulation with continuous use
4. Inverse relationship between drug concentration and drug action - ANSWER-3.
Desensitization or downregulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause:
1. Downregulation of the drug receptor
2. An exaggerated response if abruptly discontinued
3. Partial blockade of the effects of agonist drugs
4. An exaggerated response to competitive drug agonists - ANSWER-2. An exaggerated response
if abruptly discontinued
Factors that affect gastric drug absorption include:
1. Liver enzyme activity
2. Protein-binding properties of the drug molecule
3. Lipid solubility of the drug
4. Ability to chew and swallow - ANSWER-3. Lipid solubility of the drug
Drugs administered via IV:
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, NURS 615 exam 1 2025, Maryville University nursing exam
1. Need to be lipid soluble in order to be easily absorbed
2. Begin distribution into the body immediately
3. Are easily absorbed if they are nonionized
4. May use pinocytosis to be absorbed - ANSWER-2. Begin distribution into the body
immediately
When a medication is added to a regimen for a synergistic effect, the combined effect of the
drugs is:
1. The sum of the effects of each drug individually
2. Greater than the sum of the effects of each drug individually
3. Less than the effect of each drug individually
4. Not predictable, as it varies with each individual - ANSWER-2. Greater than the sum of the
effects of each drug individually
Which of the following statements about bioavailability is true?
1. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or
sustained-release mechanisms.
2. All brands of a drug have the same bioavailability.
3. Drugs that are administered more than once a day have greater bioavailability than drugs
given once daily.
4. Combining an active drug with an inert substance does not affect bioavailability. - ANSWER-1.
Bioavailability issues are especially important for drugs with narrow therapeutic
Which of the following statements about the major distribution barriers (blood-
brain or fetal-placental) is true?
3|Page
, NURS 615 exam 1 2025, Maryville University nursing exam
1. Water soluble and ionized drugs cross these barriers rapidly.
2. The blood-brain barrier slows the entry of many drugs into and from brain cells.
3. The fetal-placental barrier protects the fetus from drugs taken by the mother.
4. Lipid-soluble drugs do not pass these barriers and are safe for pregnant women. - ANSWER-2.
The blood-brain barrier slows the entry of many drugs into and from brain cells.
Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both
of these types of reactions is to:
1. Inactivate prodrugs before they can be activated by target tissues
2. Change the drugs so they can cross plasma membranes
3. Change drug molecules to a form that an excretory organ can excrete
4. Make these drugs more ionized and polar to facilitate excretion - ANSWER-3. Change drug
molecules to a form that an excretory organ can excrete
Once they have been metabolized by the liver, the metabolites may be:
1. More active than the parent drug
2. Less active than the parent drug
3. Totally "deactivated" so they are excreted without any effect
4. All of the above - ANSWER-4. All of the above
All drugs continue to act in the body until they are changed or excreted. The
ability of the body to excrete drugs via the renal system would be increased by:
1. Reduced circulation and perfusion of the kidney
4|Page
NURS 615 EXAM 1 2025, MARYVILLE UNIVERSITY NURSING EXAM
QUESTIONS, VERIFIED NURS 615 ANSWERS, NURS 615 STUDY GUIDE
PDF, NURS 615 EXAM PREP 2025, GRADED A+
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range - ANSWER-3. Onset of action
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
1. When the drug has a wide therapeutic range
2. When the drug will be administered for a short time only
3. When there is a high correlation between the dose and saturation of receptor sites
4. To determine if a drug is in the therapeutic range - ANSWER-4. To determine if a drug is in the
therapeutic range
A laboratory result indicates that the peak level for a drug is above the minimum toxic
concentration. This means that the:
1. Concentration will produce therapeutic effects
2. Concentration will produce an adverse response
3. Time between doses must be shortened
1|Page
, NURS 615 exam 1 2025, Maryville University nursing exam
4. Duration of action of the drug is too long - ANSWER-2. Concentration will produce an adverse
response
Drugs that are receptor agonists may demonstrate what property?
1. Irreversible binding to the drug receptor site
2. Upregulation with chronic use
3. Desensitization or downregulation with continuous use
4. Inverse relationship between drug concentration and drug action - ANSWER-3.
Desensitization or downregulation with continuous use
Drugs that are receptor antagonists, such as beta blockers, may cause:
1. Downregulation of the drug receptor
2. An exaggerated response if abruptly discontinued
3. Partial blockade of the effects of agonist drugs
4. An exaggerated response to competitive drug agonists - ANSWER-2. An exaggerated response
if abruptly discontinued
Factors that affect gastric drug absorption include:
1. Liver enzyme activity
2. Protein-binding properties of the drug molecule
3. Lipid solubility of the drug
4. Ability to chew and swallow - ANSWER-3. Lipid solubility of the drug
Drugs administered via IV:
2|Page
, NURS 615 exam 1 2025, Maryville University nursing exam
1. Need to be lipid soluble in order to be easily absorbed
2. Begin distribution into the body immediately
3. Are easily absorbed if they are nonionized
4. May use pinocytosis to be absorbed - ANSWER-2. Begin distribution into the body
immediately
When a medication is added to a regimen for a synergistic effect, the combined effect of the
drugs is:
1. The sum of the effects of each drug individually
2. Greater than the sum of the effects of each drug individually
3. Less than the effect of each drug individually
4. Not predictable, as it varies with each individual - ANSWER-2. Greater than the sum of the
effects of each drug individually
Which of the following statements about bioavailability is true?
1. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or
sustained-release mechanisms.
2. All brands of a drug have the same bioavailability.
3. Drugs that are administered more than once a day have greater bioavailability than drugs
given once daily.
4. Combining an active drug with an inert substance does not affect bioavailability. - ANSWER-1.
Bioavailability issues are especially important for drugs with narrow therapeutic
Which of the following statements about the major distribution barriers (blood-
brain or fetal-placental) is true?
3|Page
, NURS 615 exam 1 2025, Maryville University nursing exam
1. Water soluble and ionized drugs cross these barriers rapidly.
2. The blood-brain barrier slows the entry of many drugs into and from brain cells.
3. The fetal-placental barrier protects the fetus from drugs taken by the mother.
4. Lipid-soluble drugs do not pass these barriers and are safe for pregnant women. - ANSWER-2.
The blood-brain barrier slows the entry of many drugs into and from brain cells.
Drugs are metabolized mainly by the liver via phase I or phase II reactions. The purpose of both
of these types of reactions is to:
1. Inactivate prodrugs before they can be activated by target tissues
2. Change the drugs so they can cross plasma membranes
3. Change drug molecules to a form that an excretory organ can excrete
4. Make these drugs more ionized and polar to facilitate excretion - ANSWER-3. Change drug
molecules to a form that an excretory organ can excrete
Once they have been metabolized by the liver, the metabolites may be:
1. More active than the parent drug
2. Less active than the parent drug
3. Totally "deactivated" so they are excreted without any effect
4. All of the above - ANSWER-4. All of the above
All drugs continue to act in the body until they are changed or excreted. The
ability of the body to excrete drugs via the renal system would be increased by:
1. Reduced circulation and perfusion of the kidney
4|Page
