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CARDIAC NCLEX EXAM 2025–2026 | ACTUAL 300 EXAM QUESTIONS & CORRECT ANSWERS WITH RATIONALES | NCLEX CARDIAC MASTERY

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Master cardiac nursing with the Cardiac NCLEX Exam 2025–2026 — 300+ actual NCLEX-style questions and correct detailed answers with rationales. This high-yield resource covers everything you need: myocardial infarction (MI), heart failure (left/right-sided), ECG interpretation (atrial fibrillation, heart blocks, ST elevation), cardiac pharmacology (beta blockers, ACE inhibitors, digoxin, anticoagulants), hypertension, shock states, pericarditis, pacemakers, post-cardiac cath care, cardiac output, preload/afterload dynamics, dysrhythmias, and emergency interventions (CPR, defibrillation, ACLS prep). Based on Saunders 10th Edition and current ATI cardiac nursing frameworks. Ideal for RN students, NCLEX prep, and exit exam success — trusted, A+ rated, and pass-guaranteed.

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CARDIAC NCLEX EXAM 2025–2026 | ACTUAL 300

EXAM QUESTIONS & CORRECT ANSWERS WITH

RATIONALES | NCLEX CARDIAC MASTERY




Question 1


A nurse is caring for a 65-year-old client admitted with chest pain radiating to the left arm,

diaphoresis, and shortness of breath. The ECG shows ST-segment elevation in leads II, III, and

aVF. The client is diagnosed with an acute inferior wall myocardial infarction. The provider

orders IV morphine, oxygen, nitroglycerin, and aspirin. Thirty minutes after administering

nitroglycerin, the client becomes hypotensive (BP 84/50 mmHg) and reports dizziness. What is

the nurse’s priority action?


A. Re-administer nitroglycerin to relieve ongoing chest pain

B. Elevate the head of the bed to promote breathing

C. Place the client in Trendelenburg position and notify the provider

D. Discontinue the oxygen and reassess in 15 minutes


Correct Answer: C. Place the client in Trendelenburg position and notify the provider

Rationale: Nitroglycerin is a potent vasodilator that can significantly lower blood pressure,

,2

particularly in clients with inferior wall myocardial infarction, where right ventricular

involvement may be present. These clients are preload dependent, and vasodilation can

precipitate severe hypotension. Placing the client in Trendelenburg (or supine with legs

elevated) promotes venous return and cardiac output. The nurse must also notify the provider

immediately for further guidance. Re-administering nitroglycerin could worsen hypotension.

📚 Reference: Lewis’s Medical-Surgical Nursing, 11th ed., Ch. 34; Saunders NCLEX Review,

10th ed., Cardiac Section


Question 2


A 72-year-old client with a history of hypertension and diabetes presents with sudden onset of

chest pain, described as a “pressure” in the center of the chest that began 1 hour ago. The

ECG shows no ST elevation, but troponin I is elevated. The provider diagnoses a non-ST-

elevation myocardial infarction (NSTEMI). The nurse prepares to administer the prescribed

medications. Which of the following medications should the nurse question before

administration?


A. Enoxaparin subcutaneously

B. Metoprolol IV push

C. Aspirin 325 mg chewable

D. Sildenafil taken earlier for erectile dysfunction


Correct Answer: D. Sildenafil taken earlier for erectile dysfunction

Rationale: Sildenafil (Viagra) is a phosphodiesterase-5 inhibitor that causes vasodilation.

When combined with nitrates or other vasodilators, it can lead to life-threatening hypotension.

,3

Before giving medications like nitroglycerin, the nurse must screen for recent sildenafil use

(typically within 24–48 hours). In clients presenting with chest pain and possible MI, sildenafil

use is a critical contraindication. All other listed drugs are appropriate in managing NSTEMI.

📚 Reference: Lehne’s Pharmacology, 10th ed., p. 533; Lewis’s Med-Surg, 11th ed., Ch. 34




✅ Question 3


A client is admitted to the telemetry unit with atrial fibrillation and a heart rate of 148 bpm. The

client is asymptomatic with a stable blood pressure and no signs of heart failure. The provider

orders a loading dose of diltiazem IV. The nurse administers the medication as ordered. After

15 minutes, the heart rate decreases to 92 bpm, and the client remains hemodynamically stable.

What is the most appropriate nursing action?


A. Prepare for immediate cardioversion

B. Notify the provider of bradycardia

C. Continue monitoring the client’s response to the drug

D. Administer atropine to prevent further slowing


Correct Answer: C. Continue monitoring the client’s response to the drug

Rationale: Diltiazem, a calcium channel blocker, is commonly used for rate control in atrial

fibrillation, especially in stable clients. A decrease in heart rate from 148 to 92 bpm is a desired

therapeutic effect, not a complication. As long as the client remains stable, the nurse should

continue monitoring vitals and cardiac rhythm. Cardioversion is not indicated unless the client

becomes unstable.

, 4

📚 Reference: Lehne’s Pharmacology, 10th ed., p. 517; Saunders NCLEX Review, Cardiac

Disorders




✅ Question 4


A nurse is caring for a client who is post-op day 2 following a coronary artery bypass graft

(CABG). The client’s telemetry monitor shows sinus rhythm with occasional premature

ventricular contractions (PVCs). The client denies chest pain and vital signs are within normal

limits. Which of the following is the most appropriate nursing action?


A. Notify the rapid response team immediately

B. Assess serum potassium and magnesium levels

C. Prepare for defibrillation

D. Administer atropine 0.5 mg IV


Correct Answer: B. Assess serum potassium and magnesium levels

Rationale: Occasional PVCs after cardiac surgery are common and often related to electrolyte

imbalances, especially hypokalemia or hypomagnesemia. These disturbances increase

myocardial irritability. Since the client is stable and asymptomatic, the priority is to assess labs

and correct underlying causes. No emergent interventions are warranted unless PVCs become

frequent or the rhythm deteriorates.

📚 Reference: Lewis’s Medical-Surgical Nursing, 11th ed., Ch. 35; ATI RN Cardiac Nursing

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