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i-Human Case #4: 15-Year-Old Male withi-Human Case #4: 15-Year-Old Male with Progressive Dyspnea, Chronic Cough, and Wheezing – Clinical Evaluation of Suspected COPD with Cardiac and Environmental Risk Factors /I Human Case week #4 A 15 Year Old Male Reas

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i-Human Case #4: 15-Year-Old Male with ogressive Dyspnea, Chronic Cough, and Wheezing – Clinical Evaluation of SPruspected COPD with Cardiac and Environmental Risk Factors /I Human Case week #4 A 15 Year Old Male Reason For Encounter: Shortness Of Breath

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Voorbeeld van de inhoud

,Patient Information

 Name: Jacob Miller

 Age: 15 years

 Gender: Male

 Chief Complaint: Progressive dyspnea, chronic cough, and
wheezing for 3 months

 Setting: Primary care clinic

 Date and Time: July 16, 2025, 09:52 AM EAT



Case Overview

This case study, designed for i-Human Case #4, focuses on a 15-year-old
male presenting with a 3-month history of progressive dyspnea, chronic
cough, and wheezing, prompting evaluation for suspected chronic
obstructive pulmonary disease (COPD) while considering cardiac and
environmental risk factors. COPD is rare in adolescents, making this
presentation unusual and necessitating a broad differential to identify
the underlying cause. The objectives are to:

, Obtain a comprehensive history to elucidate the onset,
characteristics, triggers, and impact of respiratory symptoms, as
well as relevant environmental, social, and family history.

 Perform a targeted physical examination, focusing on respiratory,
cardiac, and systemic findings to identify signs of obstructive lung
disease or alternative etiologies.

 Formulate a broad differential diagnosis, prioritizing based on
clinical findings, patient age, and risk factors, while addressing the
atypical nature of COPD-like symptoms in an adolescent.

 Select and interpret appropriate diagnostic tests to confirm the
diagnosis and rule out serious conditions, such as cardiac
pathology, genetic disorders, or infections.

 Develop an evidence-based, patient-centered management plan,
addressing symptoms, environmental triggers, and patient/family
education to optimize outcomes.
The case emphasizes distinguishing asthma from rare conditions
like alpha-1 antitrypsin deficiency (A1ATD), cardiac causes, and
environmental triggers, recognizing red flags, and tailoring
interventions to an adolescent’s lifestyle and family dynamics.

, Case Details

History of Present Illness (HPI)Jacob Miller, a 15-year-old male, presents
to the primary care clinic with a chief complaint of progressive dyspnea,
chronic cough, and wheezing for 3 months. The following detailed
history was obtained:

 Onset: Symptoms began gradually in April 2025, initially mild but
progressively worsening over the past 3 months.

 Dyspnea:

 Severity: Moderate, rated 5/10 at rest, escalating to 7/10
with exertion (e.g., running during soccer practice, climbing
two flights of stairs).

 Characteristics: Described as “can’t catch my breath” or
“lungs feel tight,” limiting physical activity and causing
distress during exertion.

 Timing: Present daily, most pronounced in the morning and
during/after physical activity. Worsens with exposure to cold
air, dust, or smoky environments.

 Associated Features: Accompanied by a sensation of chest
tightness during exertion, but no sharp chest pain or
radiation.

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