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ATI Pharmacology Proctored Exam 2025–2026 | Verified Test Bank with 100% Correct Answers & Detailed Rationales | NCLEX A+ Guaranteed

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This is a fully verified and up-to-date ATI Pharmacology Proctored Exam 2025–2026 Test Bank with 100% correct answers and detailed rationales. Designed in true NCLEX-style format, this complete study pack includes 100 high-yield questions covering all key pharmacology topics tested on the ATI RN/PN exam. Topics include: medication classifications, side effects, adverse reactions, nursing interventions, dosage calculations, high-alert medications, and patient education. Whether you're preparing for the RN or PN ATI pharmacology proctored exam, this resource is perfect for guaranteed success. Used by nursing students at Chamberlain, WGU, ECPI, Herzing, and more. Covers official ATI 2025 content and NCLEX pharmacology standards. GRADED A+ | NCLEX-STYLE QUESTIONS | LATEST 2025–2026 UPDATE | PASS GUARANTEED

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1




ATI PHARMACOLOGY PROCTORED EXAM 2025-2026 |

VERIFIED TEST BANK WITH CORRECT ANSWERS &

RATIONALES | GRADED A+ PASS GUARANTEED




1. A nurse is caring for a 72-year-old client admitted with atrial fibrillation who is

prescribed digoxin 0.25 mg orally daily. The client also takes furosemide and has a history

of chronic kidney disease. During the morning assessment, the nurse notes the client is

complaining of nausea, general weakness, and blurred vision. Vital signs reveal a heart rate

of 52 bpm and blood pressure of 122/78 mmHg. Laboratory results show a potassium level

of 3.0 mEq/L and a serum digoxin level of 2.4 ng/mL. Which of the following actions should

the nurse take first based on these findings?

A. Administer potassium chloride as prescribed

B. Hold the next dose of digoxin and notify the provider

C. Encourage the client to increase fluid intake

D. Continue routine monitoring and reassess in 4 hours


Correct Answer: B. Hold the next dose of digoxin and notify the provider

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Rationale: The client's symptoms (nausea, weakness, blurred vision), bradycardia, low

potassium level, and elevated digoxin level strongly indicate digoxin toxicity. The first nursing

action should be to withhold the medication and notify the provider for further evaluation.

Administering potassium may help correct hypokalemia, but addressing the digoxin toxicity

takes priority. Continuing the medication could worsen toxicity and lead to cardiac dysrhythmias

or death. Prompt provider notification ensures timely treatment, which may include

administering digoxin immune Fab.

Test-Taking Strategy: Recognize classic signs of digoxin toxicity. Prioritize patient safety

using the ABC approach (Airway, Breathing, Circulation) — bradycardia and toxicity pose an

immediate circulatory threat.

PTS: 1 | DIF: Apply | REF: ATI Pharmacology Review Module 2025 | OBJ: Medication Safety

& Monitoring




2. A nurse in the emergency department is preparing to administer naloxone to a client

who was found unresponsive at home with shallow respirations, pinpoint pupils, and a

respiratory rate of 6 breaths/min. The client’s partner reports the client has a history of

chronic back pain and was prescribed oxycodone but had recently increased his dose due

to worsening pain. The naloxone is to be given intranasally, and the nurse prepares to

administer the drug per standing orders. Which of the following outcomes best indicates

that the medication has been effective?

A. The client becomes agitated and hypertensive

B. The client’s respiratory rate increases to 14 breaths per minute

,3

C. The client reports a reduction in back pain

D. The client requests to sleep undisturbed


Correct Answer: B. The client’s respiratory rate increases to 14 breaths per minute


Rationale: Naloxone is an opioid antagonist that rapidly reverses the effects of opioid overdose,

primarily respiratory depression. An increased respiratory rate is the most direct and objective

sign of effectiveness. Although naloxone can cause agitation or hypertension as a side effect,

these do not measure its success. The goal is to restore adequate spontaneous breathing. Pain

relief or sedation do not indicate reversal. Nurses should continue to monitor the client since

naloxone’s half-life is shorter than many opioids, increasing the risk of rebound toxicity.

Test-Taking Strategy: Choose outcomes that directly reflect the therapeutic intent of the drug.

Focus on airway and breathing restoration in overdose situations.

PTS: 1 | DIF: Analyze | REF: ATI Pharmacology 2025 | OBJ: Emergency Medication

Administration




3. A nurse is reviewing discharge instructions with a client who has been prescribed

warfarin therapy following hospitalization for a deep vein thrombosis (DVT). The client is

also taking several over-the-counter supplements, including ginkgo biloba, garlic, and

vitamin E. During teaching, the client expresses confusion about diet and medication

interactions. Which of the following client statements indicates a need for further teaching

about warfarin therapy?

A. "I will get my INR checked regularly."

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B. "I can continue taking ginkgo biloba for my memory."

C. "I should use a soft-bristled toothbrush."

D. "I will try to avoid foods that are very high in vitamin K."


Correct Answer: B. "I can continue taking ginkgo biloba for my memory."


Rationale: Ginkgo biloba, garlic, and vitamin E all increase the risk of bleeding when taken

with warfarin due to their antiplatelet or anticoagulant properties. Clients should be taught to

avoid these supplements or consult their provider before use. An increased International

Normalized Ratio (INR) can result in dangerous bleeding events, particularly if warfarin is

potentiated by interactions. A soft-bristled toothbrush and avoiding high vitamin K intake are

correct practices. Ongoing INR monitoring is essential for warfarin safety.

Test-Taking Strategy: Identify the option that indicates a lack of understanding of drug–herb

interactions and safety precautions.

PTS: 1 | DIF: Apply | REF: ATI Pharmacology Module 2025 | OBJ: Safe Use of

Anticoagulants


\


4. A nurse is caring for a pediatric client who has been diagnosed with acute lymphoblastic

leukemia and is currently receiving methotrexate therapy. The provider has ordered

leucovorin rescue therapy to be administered following chemotherapy. The nurse receives a

call from the pharmacy stating that the leucovorin dose is delayed. Which of the following

is the nurse’s best response in this situation?

A. Wait for the pharmacy to send the medication when it’s ready

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