California Medical Laboratory
Technician Licensing Exam Questions
And Correct Answers (Verified Answers)
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1. What is the normal reference range for adult hemoglobin (Hb) in males?
A. 10–12 g/dL
B. 13.5–17.5 g/dL
C. 11–14 g/dL
D. 8–11 g/dL
Answer: B
Normal adult male hemoglobin ranges from 13.5 to 17.5 g/dL. This helps
determine oxygen-carrying capacity of the blood.
2. Which of the following microorganisms is most commonly associated
with urinary tract infections (UTIs)?
A. Staphylococcus aureus
B. Klebsiella pneumoniae
C. Escherichia coli
D. Pseudomonas aeruginosa
Answer: C
,E. coli is responsible for approximately 80–85% of community-acquired
UTIs.
3. What is the anticoagulant in a lavender-top blood collection tube?
A. Sodium citrate
B. EDTA
C. Heparin
D. Fluoride
Answer: B
EDTA prevents clotting by binding calcium and is used primarily for
hematology testing.
4. Which test is used to monitor long-term glucose control in diabetic
patients?
A. Fasting glucose
B. Hemoglobin A1c
C. OGTT
D. Insulin level
Answer: B
Hemoglobin A1c reflects average blood glucose over 2–3 months, useful for
diabetes monitoring.
5. Which stain is used for differentiating WBCs in a peripheral blood
smear?
A. Gram stain
B. Wright's stain
C. Ziehl-Neelsen stain
D. India ink
,Answer: B
Wright's stain allows for clear differentiation of WBCs, RBCs, and platelets
in smears.
6. The purpose of quality control (QC) in the clinical lab is to:
A. Increase revenue
B. Reduce staff
C. Ensure accuracy and reliability of test results
D. Shorten turnaround times
Answer: C
QC procedures confirm that instruments and methods are functioning
correctly, ensuring valid results.
7. What biosafety level is required for handling Mycobacterium
tuberculosis cultures?
A. BSL-1
B. BSL-2
C. BSL-3
D. BSL-4
Answer: C
BSL-3 is used for agents that may cause serious or potentially lethal
diseases via inhalation, like M. tuberculosis.
8. A positive Coombs test indicates:
A. Leukemia
B. Autoimmune hemolysis
C. Iron deficiency anemia
D. Platelet dysfunction
, Answer: B
A positive Coombs test detects antibodies attached to RBCs, often seen in
autoimmune hemolytic anemia.
9. Which of the following is a confirmatory test for HIV?
A. ELISA
B. Western blot
C. Rapid antigen test
D. PCR
Answer: B
Western blot confirms the presence of HIV antibodies after an initial
positive ELISA screen.
10. The presence of ketones in urine most commonly indicates:
A. Renal failure
B. Starvation or uncontrolled diabetes
C. Hematuria
D. UTI
Answer: B
Ketones appear in urine when fat metabolism is increased, as seen in
starvation or diabetic ketoacidosis.
11. Which immunoglobulin is first produced in response to an infection?
A. IgA
B. IgM
C. IgG
D. IgE
Technician Licensing Exam Questions
And Correct Answers (Verified Answers)
Plus Rationales 2025 Q&A | Instant
Download Pdf
1. What is the normal reference range for adult hemoglobin (Hb) in males?
A. 10–12 g/dL
B. 13.5–17.5 g/dL
C. 11–14 g/dL
D. 8–11 g/dL
Answer: B
Normal adult male hemoglobin ranges from 13.5 to 17.5 g/dL. This helps
determine oxygen-carrying capacity of the blood.
2. Which of the following microorganisms is most commonly associated
with urinary tract infections (UTIs)?
A. Staphylococcus aureus
B. Klebsiella pneumoniae
C. Escherichia coli
D. Pseudomonas aeruginosa
Answer: C
,E. coli is responsible for approximately 80–85% of community-acquired
UTIs.
3. What is the anticoagulant in a lavender-top blood collection tube?
A. Sodium citrate
B. EDTA
C. Heparin
D. Fluoride
Answer: B
EDTA prevents clotting by binding calcium and is used primarily for
hematology testing.
4. Which test is used to monitor long-term glucose control in diabetic
patients?
A. Fasting glucose
B. Hemoglobin A1c
C. OGTT
D. Insulin level
Answer: B
Hemoglobin A1c reflects average blood glucose over 2–3 months, useful for
diabetes monitoring.
5. Which stain is used for differentiating WBCs in a peripheral blood
smear?
A. Gram stain
B. Wright's stain
C. Ziehl-Neelsen stain
D. India ink
,Answer: B
Wright's stain allows for clear differentiation of WBCs, RBCs, and platelets
in smears.
6. The purpose of quality control (QC) in the clinical lab is to:
A. Increase revenue
B. Reduce staff
C. Ensure accuracy and reliability of test results
D. Shorten turnaround times
Answer: C
QC procedures confirm that instruments and methods are functioning
correctly, ensuring valid results.
7. What biosafety level is required for handling Mycobacterium
tuberculosis cultures?
A. BSL-1
B. BSL-2
C. BSL-3
D. BSL-4
Answer: C
BSL-3 is used for agents that may cause serious or potentially lethal
diseases via inhalation, like M. tuberculosis.
8. A positive Coombs test indicates:
A. Leukemia
B. Autoimmune hemolysis
C. Iron deficiency anemia
D. Platelet dysfunction
, Answer: B
A positive Coombs test detects antibodies attached to RBCs, often seen in
autoimmune hemolytic anemia.
9. Which of the following is a confirmatory test for HIV?
A. ELISA
B. Western blot
C. Rapid antigen test
D. PCR
Answer: B
Western blot confirms the presence of HIV antibodies after an initial
positive ELISA screen.
10. The presence of ketones in urine most commonly indicates:
A. Renal failure
B. Starvation or uncontrolled diabetes
C. Hematuria
D. UTI
Answer: B
Ketones appear in urine when fat metabolism is increased, as seen in
starvation or diabetic ketoacidosis.
11. Which immunoglobulin is first produced in response to an infection?
A. IgA
B. IgM
C. IgG
D. IgE
