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Pharm HESI Practice Exam 2025–2026 | Updated Questions & Verified Answers with Rationales | Guaranteed Pass

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Get fully prepared for your upcoming HESI Pharmacology exam with this 2025–2026 updated practice exam pack, featuring real exam-style questions and verified answers with detailed rationales. This resource is perfect for nursing students aiming to boost their score and pass with confidence. 75+ Updated HESI Pharmacology Questions (2025–2026) Correct Answers with Detailed Rationales Covers Drug Classifications, Side Effects, Dosage Calculations, Interactions & More Based on the Latest HESI RN Pharmacology Blueprint Perfect for HESI, NCLEX, Midterms & Exit Exams Ideal for RN, BSN, and LPN Pharmacology Prep Instant Digital Download – Study Anytime, Anywhere A+ Rated Content | 100% Pass Guarantee This latest 2025–2026 HESI Pharmacology practice test is your shortcut to mastering core concepts and passing your exam with flying colors!

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Pharm HESI Practice Exam Latest update(QUESTIONS AND ANSWERS) 2
Study online at https://quizlet.com/_efsmsi

The nurse is caring for a client who has
taken atenolol for 2 years. The health-
care provider recently changed the med-
ication to enalapril to manage the client's
blood pressure. Which instruction should
the nurse provide the client regarding the
new medication? D. Rise slowly when getting out of bed or
chair.
A. Take the medication at bedtime.
B. Report presence of increased bruis-
ing.
C. Check pulse before taking medication.
D. Rise slowly when getting out of bed or
chair.
A female client calls the clinic and talks
with the nurse to inquire about a pos-
sible reaction after taking amoxicillin for
5 days. She reports having vaginal dis-
comfort, itching, and a white discharge.
The nurse should discuss which action
with the client?
C. Consult with healthcare provider
A. Discontinue the antibiotic because about another treatment for this effect.
original symptoms have subsided.
B. Continue taking medication until fin-
ished until the symptoms subside.
C. Consult with healthcare provider
about another treatment for this effect.
D. Use an over-the-counter (OTC) vagi-
nal wash to flush out the secretions.
The nurse is making early morning
rounds on a group of clients when a
client begins exhibiting symptoms of an
acute asthma attack. The nurse admin-
C, D
isters a PRN prescription for a Beta 2
receptor agonist agent. Which client re-
sponse should the nurse expect?



, Pharm HESI Practice Exam Latest update(QUESTIONS AND ANSWERS) 2
Study online at https://quizlet.com/_efsmsi
A. Tachycardia.
B. Increased blood pressure.
C. Rapid resolution of wheezing.
D. Improved pulse oximetry values.
E. Reduce fever airway inflammation.
A client prescribed atenolol has a blood
pressure of 120/68 mmHg, displaying
a sinus bradycardia with a rate of 58
beats/minute, and a P-R interval of 0.24.
Which action should the nurse take?

A. Lower the head of the bed and as-
B. Give the medication as prescribed and
sess the client for orthostatic vital sign
continue to monitor the client.
changes.
B. Give the medication as prescribed and
continue to monitor the client.
C. Prepare to administer atropine sulfate
IV push.
D. Hold the prescribed dose and contact
the healthcare provider.
The nurse is preparing the 0900 dose of
losartan (Cozaar), an angiotensin II re-
ceptor blocker (ARB), for a client with hy-
pertension and heart failure. The nurse
reviews the client's laboratory results
and notes that the client's serum potas-
sium level is 5.9 mEq/L. Which action A. Withhold the scheduled dose.
should the nurse take first?

A. Withhold the scheduled dose.
B. Check the client's apical pulse.
C. Notify the healthcare provider.
D. Repeat the serum potassium level.

Upon admission to the emergency cen- 1. Albuterol (Proventil) puffs.
ter, an adult client with acute status asth- 2. Salmeterol (Serevent Diskus).
maticus is prescribed this series of med- 3. Prednisone (Deltasone) orally.
ications. In which order should the nurse 4. Gentamicin (Garamycin) IM.


, Pharm HESI Practice Exam Latest update(QUESTIONS AND ANSWERS) 2
Study online at https://quizlet.com/_efsmsi
administer the prescribed medications?
(Arrange from first to last.)
An adult client is given a prescription for
a scopolamine patch (Transderm Scop)
to prevent motion sickness while on
a cruise. Which information should the
nurse provide to the client?

A. Apply the patch at least 4 hours prior A. Apply the patch at least 4 hours prior
to departure. to departure.
B. Change the patch every other day
while on the cruise.
C. Place the patch on a hairless area at
the base of the skull.
D. Drink no more than 2 alcoholic drinks
during the cruise.
A client with giardiasis is taking metron-
idazole (Flagyl) 2 grams PO. Which in-
formation should the nurse include in the
client's instruction?

A. Notify the clinic of any changes in the D. Take the medication with food.
color of urine.
B. Avoid overexposure to the sun.
C. Stop the medication after the diarrhea
resolves.
D. Take the medication with food.
A female client with rheumatoid arthritis
takes ibuprofen (Motrin) 600 mg PO 4
times a day. To prevent gastrointestinal
bleeding, misoprostol (Cytotec) 100 mcg
PO is prescribed. Which information is
most important for the nurse to include A. Use contraception during intercourse.
in client teaching?

A. Use contraception during intercourse.
B. Ensure the Cytotec is taken on an
empty stomach.

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