Psychopharmacology Exam 4 – NURS 752 (Liberty University, PMHNP) – 130 Practice Questions with Answers & Rationales

Psychopharmacology Exam 4 – 130 Real Practice Questions
with Answers & Rationales (NURS 752, PMHNP)
Conquer Exam 4 of NURS 752 Psychopharmacology with this comprehensive
practice question pack designed for Liberty University PMHNP students and
other advanced nursing programs. This bundle includes:

 ✅ 130 high-yield multiple choice questions
 💊 Covers Mood Stabilizers, Antipsychotics, Anxiolytics, Stimulants,
Geriatrics, Pediatrics, Drug Interactions, & Case Scenarios
 📘 Each question includes correct answers and rationales for fast,
effective review
 💡 Perfect for Exam 4 prep, class quizzes, or board review
 🧠 Created with actual clinical decision-making and prescribing guidelines in
mind

Whether you're cramming for the test or reviewing at your own pace, this set
ensures you're ready for any psychopharmacology challenge.



Q1: Mood Stabilizers

Question: A patient with bipolar I disorder is prescribed lithium. Which of the following lab
values requires immediate intervention?
A. Sodium 140 mEq/L
B. Lithium level 0.6 mEq/L
C. Creatinine 2.0 mg/dL
D. TSH 2.0 µIU/mL
Correct Answer: C. Creatinine 2.0 mg/dL
Rationale: Elevated creatinine indicates impaired renal function, which increases the risk of
lithium toxicity.



Q2: Antipsychotics

Question: Which antipsychotic carries the highest risk for agranulocytosis?
A. Risperidone
B. Haloperidol
C. Clozapine
D. Aripiprazole

,Correct Answer: C. Clozapine
Rationale: Clozapine is associated with agranulocytosis, requiring frequent WBC monitoring.



Q3: Anxiolytics

Question: Which medication is most appropriate for long-term treatment of generalized anxiety
disorder (GAD)?
A. Alprazolam
B. Diazepam
C. Buspirone
D. Clonazepam
Correct Answer: C. Buspirone
Rationale: Buspirone has no abuse potential and is suitable for long-term use in GAD.



Q4: Stimulants

Question: A child diagnosed with ADHD experiences appetite suppression from
methylphenidate. What is the best intervention?
A. Discontinue the medication
B. Give medication at bedtime
C. Switch to atomoxetine
D. Increase the dose
Correct Answer: C. Switch to atomoxetine
Rationale: Atomoxetine is non-stimulant and has less impact on appetite.



Q5: Pediatrics

Question: Which class of medication is FDA-approved for pediatric depression?
A. MAOIs
B. TCAs
C. SSRIs
D. SNRIs
Correct Answer: C. SSRIs
Rationale: Fluoxetine is FDA-approved for pediatric depression; SSRIs are preferred due to
safety profile.



Q6: Geriatrics

, Question: A 78-year-old with dementia is started on risperidone for agitation. What is the
primary concern?
A. Weight gain
B. QT prolongation
C. Increased mortality
D. Hyperprolactinemia
Correct Answer: C. Increased mortality
Rationale: Antipsychotics increase the risk of death in elderly dementia patients; use with
caution.



Q7: Drug Interactions

Question: Which SSRI is most likely to cause drug-drug interactions due to CYP450 inhibition?
A. Sertraline
B. Fluoxetine
C. Escitalopram
D. Paroxetine
Correct Answer: B. Fluoxetine
Rationale: Fluoxetine strongly inhibits CYP2D6, increasing risk of interactions.



Q8: Case-Based Scenario

Question: A patient on clozapine reports fever and sore throat. What is the first action?
A. Increase dose
B. Check CBC with differential
C. Prescribe antibiotics
D. Discontinue clozapine immediately
Correct Answer: B. Check CBC with differential
Rationale: Sore throat and fever may indicate agranulocytosis; lab confirmation is essential.



Q9: Mood Stabilizers

Question: Which medication requires regular liver function testing?
A. Lithium
B. Lamotrigine
C. Valproate
D. Oxcarbazepine
Correct Answer: C. Valproate
Rationale: Valproate can cause hepatotoxicity, especially in young children.