Questions and CORRECT Answers
1. How do MOA: inhibits the infiltration and phagocytosis of leukocytes, thus decreasing the
antigout medica- breakdown of uric acid to urate crystals.
tions work?
2. Deposition of pain and inflammation
urate crystals
causes
3. What is anti-gout medication
Colchicine
4. How does MOA: inhibits inflammation, reducing pain and swelling
Colchicine work?
5. Common side GI problems (diarrhea) use with caution in elderly
effects of Also can cause blood dyscrasias & abdominal pain
Colchicine
6. Patient edu- Almost always causes some degree of diarrhea
cation with May be given with food & milk to decrease GI issues
Colchicine Avoid beer, ale, & wine: may cause a gout attack
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
7. Low dose of Low dose colchicine is 1.2mg followed by 0.6mg one hour later or 1.8 milligrams
Colchicine total
8. High dose of high dose colchicine is 1.2mg followed by 0.6mg every four to six hours; or 4.8mg
Colchicine total.
9. Difference be- The difference between the two is low dose is as effective as high dose with a
tween high dose lower side effect profile.
, Pharm test 3 Maryville NURS 615 UPDATED ACTUAL
Questions and CORRECT Answers
and low dose
Colchicine
10. Lab values to Check renal function test, BUN, Creatine, & CBC
monitor with
Colchicine
11. Patient educa- Gout may worsen with therapy initially
tion with Febuxo-
stat (Uloric)
12. Dietary changes Avoid beer, ale, & wine
to decrease gout Increase fluid intake: increases excretion of uric acid
attacks and uric Avoid smoked meats & high-protein diets
acid deposits.
13. WHO 3 step lad-
der for pain med-
ication
14. What is not a first Narcotics
line for pain med-
ication?
15. Recommenda- You want to start with NSAIDs first and then work your way up from there.
tions for pain
treatment
16. types of Corticos- Prednisone, Cortisone, Dexamethasone
teroid treatment
17. how do Corticos- Suppress the inflammatory & immune systems by inhibiting the synthesis of
teroids work? chemical mediators.
, Pharm test 3 Maryville NURS 615 UPDATED ACTUAL
Questions and CORRECT Answers
18. what are the Prostaglandins, leukotrienes, & histamines
chemical media-
tors that Corti-
costeroids work
on?
19. Corticosteroids Decreases inflammation which decreases swelling, warmth, redness, & pain.
and
inflammation
20. Uses for corticos- Addison's disease, hormone replacement, cancer therapy
teroid treatment SLE, arthritis, IBD, & to suppress graft rejection
21. contraindica- Systemic fungal infections & with live vaccine
tions for
corticosteroid
treatment
22. Use corticos- Pregnancy, kids, HTN, heart failure, renal impairment, & with infections resistant
teroids cautious- to treatment
ly with:
23. Patient educa- Don't discontinue abruptly, doses may need increased during stress, symptoms
tion with corti- of Cushing's and GI bleeding
costeroids
24. Problem with The main thing you want to worry about is osteoporosis it can also worsen diabetic
taking Corti- control and patients should report any tarry black stools or abdominal pain.
costeroids for
greater than 6
months
25.