NU 560 Exam 3 Questions With Complete Solutions
1. Contraindications to using DOACs Correct Answer a.
Xarelto is contraindicated with poor renal function
1. How food affects bioavailability of the protease inhibitor
indinavir Correct Answer a. Causes a decrease of
bioavailability
b. Take on an empty stomach
1. How to transition from warfarin to a direct oral anticoagulant
Correct Answer a. Enoxaparin: 1 mg/kg subcutaneous q 12 hrs
or 1.5 mg/kg daily subcutaneous for inpatients with DVT (with
or without PE)
b. Warfarin: Bridge with LMWH or UFH for < 5 days
c. Apixaban: 10 mg BID for 7 days followed by 5 mg B
1. MOA of beta-lactamase inhibitors. Correct Answer a. BL
Inhibitors: irreversibly bind to most beta-lactamase enzymes,
protecting Beta-Lactam from degradation
1. MOA of macrolides Correct Answer a. Inhibition of
bacterial protein synthesis by binding to the 50S ribosomal
subunit
1. Safety of anticoagulants in pregnancy Correct Answer a.
Heparin can be used in pregnancy
b. Warfarin- completely contraindicated
, 1. What causes antimicrobial resistance and how it occurs
Correct Answer a. Bacterial enzyme productions: ex beta
lactamase in the most common
b. Alterations of bacterial cell membranes- inhibiting abx from
entering the cell
c. Alterations for abx's target site of action- mutations after the
ribosomal binding site
d. Alteration of target enzyme
e. Overproduction of target enzymes leading to resistance
1. What classes of antimicrobials can cause hepatotoxicity
Correct Answer fluroquinolones, tetracyclines
1. what meds are used to treat pernicious anemia Correct
Answer a. its a Vitamin B12 deficiency
b. Cyanacobalamin
1. what recombinant EPO is used to treat Correct Answer a.
treatment of anemia due to chronic renal failure, HIV patients,
and chemotherapy admin
Adverse events of Epogen Correct Answer HTN, headache,
seizure, nausea, edema, fatigue
common properties of anti platelet therapy Correct Answer
used to prevent stroke
add on therapy for mechanical heart valves
ASA and plavix
common properties of direct oral anticoagulants Correct
Answer preventing ischemic stroke
1. Contraindications to using DOACs Correct Answer a.
Xarelto is contraindicated with poor renal function
1. How food affects bioavailability of the protease inhibitor
indinavir Correct Answer a. Causes a decrease of
bioavailability
b. Take on an empty stomach
1. How to transition from warfarin to a direct oral anticoagulant
Correct Answer a. Enoxaparin: 1 mg/kg subcutaneous q 12 hrs
or 1.5 mg/kg daily subcutaneous for inpatients with DVT (with
or without PE)
b. Warfarin: Bridge with LMWH or UFH for < 5 days
c. Apixaban: 10 mg BID for 7 days followed by 5 mg B
1. MOA of beta-lactamase inhibitors. Correct Answer a. BL
Inhibitors: irreversibly bind to most beta-lactamase enzymes,
protecting Beta-Lactam from degradation
1. MOA of macrolides Correct Answer a. Inhibition of
bacterial protein synthesis by binding to the 50S ribosomal
subunit
1. Safety of anticoagulants in pregnancy Correct Answer a.
Heparin can be used in pregnancy
b. Warfarin- completely contraindicated
, 1. What causes antimicrobial resistance and how it occurs
Correct Answer a. Bacterial enzyme productions: ex beta
lactamase in the most common
b. Alterations of bacterial cell membranes- inhibiting abx from
entering the cell
c. Alterations for abx's target site of action- mutations after the
ribosomal binding site
d. Alteration of target enzyme
e. Overproduction of target enzymes leading to resistance
1. What classes of antimicrobials can cause hepatotoxicity
Correct Answer fluroquinolones, tetracyclines
1. what meds are used to treat pernicious anemia Correct
Answer a. its a Vitamin B12 deficiency
b. Cyanacobalamin
1. what recombinant EPO is used to treat Correct Answer a.
treatment of anemia due to chronic renal failure, HIV patients,
and chemotherapy admin
Adverse events of Epogen Correct Answer HTN, headache,
seizure, nausea, edema, fatigue
common properties of anti platelet therapy Correct Answer
used to prevent stroke
add on therapy for mechanical heart valves
ASA and plavix
common properties of direct oral anticoagulants Correct
Answer preventing ischemic stroke
