ASCP-CHEMISTRY SECTION QUESTIONS
WITH CORRECT ANSWERS 2025-2026
Aldosterone is released by the adrenal cortex upon stimulation by:
A. Renin
B. Angiotensinogen
C. Angiotenisinogen I
D. Angiotensinogen II - CORRECT ANSWER -D. Angiotensinogen II
Clinical Assays for tumor markers are most important for:
A. screening for the presence of cancer
B. monitoring the course of known cancer
C. confirming the absence of disease
D. identifying patients at risk for cancer - CORRECT ANSWER -B. Monitoring the course of known cancer
Detection of which of the following substances is most useful to monitor the course of a patient with testic
ular cancer?
A. alpha-fetoprotein
B. carcinoembryonic antigen
C. prolactin
D. testosterone - CORRECT ANSWER -A. alpha-fetoprotein
Increased concentrations of alpha-fetoprotein (AFP) in adults are most characteristically associated with:
A. hepatocellular carcinoma
B. alcoholic cirrhosis
C. chronicsactive hepatitis
D. multiple myeloma - CORRECT ANSWER -A. hepatocellular carcinoma
,Carcinoembryonic antigen (CEA) issmost likely to be produced in a maignancy involving the:
A. Brain
B. Testes
C. Bone
D. Colon - CORRECT ANSWER -D. Colon
Which of the following is useful in the detection an managementsof carcinoma of the prostate?
A. total prostate-specific antigen
B. prostatic acid phosphatase
C. human chorionic gonadotropin
D. alpha-fetoprotein - CORRECT ANSWER -A. total prostate-specific antigen
Which of the following statements most correctly describes the utility of clinical laboratory assays for tum
or markers?
A. tumor markers are useful to screen asymptomatic patients for tumors
B. tumor markers are highly specific
C. tumor markerssindicate the likelihood of an individual developing a tumor
D. tumors are useful in tracking the efficacy of treatment - CORRECT ANSWER -
D. tumors are useful in tracking the efficacy of treatment
Cancer antigen 125 (CA 125) is a tumor marker associated with:
A. breast carcinoma
B. colon cancer
C. lung cancer
, D. ovarian and endometrial carcinoma - CORRECT ANSWER -D. ovarian and endometrial carcinoma
In addition to carcinoma of the prostate, elevated prostate-specific antigen (PSA) can occur due to:
A. aspirin therapy
B. exogenous steroid use
C. benign prostatic hyperplasia
D. statin therapy (cholesterol lowering drugs) -sCORRECT ANSWER -C. benign prostatic hyperplasia
A drug has a half-life of 6 hours. If a dose is given every 6 hours, a steady-
state drugslevel would usually be achieved in:
A. 3-5 hours
B. 10-12 hours
C. 24-42 hours
D. 48-50 hours - CORRECT ANSWER -C. 24-42 hours
The drug procainamide is prescribed to treat cardiac arrhythmia. What biologically active liver metabolite
of procainamide is often measured simultaneously?
A. phenobarbitol
B. quinidine
C. N-acetyl procainamide (NAPA)
D. lidocaine - CORRECT ANSWER -C. N-acetyl procainamide (NAPA)
Cocaine is metabolized to:
A. carbamazepine
B. codeine
WITH CORRECT ANSWERS 2025-2026
Aldosterone is released by the adrenal cortex upon stimulation by:
A. Renin
B. Angiotensinogen
C. Angiotenisinogen I
D. Angiotensinogen II - CORRECT ANSWER -D. Angiotensinogen II
Clinical Assays for tumor markers are most important for:
A. screening for the presence of cancer
B. monitoring the course of known cancer
C. confirming the absence of disease
D. identifying patients at risk for cancer - CORRECT ANSWER -B. Monitoring the course of known cancer
Detection of which of the following substances is most useful to monitor the course of a patient with testic
ular cancer?
A. alpha-fetoprotein
B. carcinoembryonic antigen
C. prolactin
D. testosterone - CORRECT ANSWER -A. alpha-fetoprotein
Increased concentrations of alpha-fetoprotein (AFP) in adults are most characteristically associated with:
A. hepatocellular carcinoma
B. alcoholic cirrhosis
C. chronicsactive hepatitis
D. multiple myeloma - CORRECT ANSWER -A. hepatocellular carcinoma
,Carcinoembryonic antigen (CEA) issmost likely to be produced in a maignancy involving the:
A. Brain
B. Testes
C. Bone
D. Colon - CORRECT ANSWER -D. Colon
Which of the following is useful in the detection an managementsof carcinoma of the prostate?
A. total prostate-specific antigen
B. prostatic acid phosphatase
C. human chorionic gonadotropin
D. alpha-fetoprotein - CORRECT ANSWER -A. total prostate-specific antigen
Which of the following statements most correctly describes the utility of clinical laboratory assays for tum
or markers?
A. tumor markers are useful to screen asymptomatic patients for tumors
B. tumor markers are highly specific
C. tumor markerssindicate the likelihood of an individual developing a tumor
D. tumors are useful in tracking the efficacy of treatment - CORRECT ANSWER -
D. tumors are useful in tracking the efficacy of treatment
Cancer antigen 125 (CA 125) is a tumor marker associated with:
A. breast carcinoma
B. colon cancer
C. lung cancer
, D. ovarian and endometrial carcinoma - CORRECT ANSWER -D. ovarian and endometrial carcinoma
In addition to carcinoma of the prostate, elevated prostate-specific antigen (PSA) can occur due to:
A. aspirin therapy
B. exogenous steroid use
C. benign prostatic hyperplasia
D. statin therapy (cholesterol lowering drugs) -sCORRECT ANSWER -C. benign prostatic hyperplasia
A drug has a half-life of 6 hours. If a dose is given every 6 hours, a steady-
state drugslevel would usually be achieved in:
A. 3-5 hours
B. 10-12 hours
C. 24-42 hours
D. 48-50 hours - CORRECT ANSWER -C. 24-42 hours
The drug procainamide is prescribed to treat cardiac arrhythmia. What biologically active liver metabolite
of procainamide is often measured simultaneously?
A. phenobarbitol
B. quinidine
C. N-acetyl procainamide (NAPA)
D. lidocaine - CORRECT ANSWER -C. N-acetyl procainamide (NAPA)
Cocaine is metabolized to:
A. carbamazepine
B. codeine
