Know the route of administration for newer agent asenapine (Saphris) and what
instructions should be given to the patient regarding administration. -
ANSWER-Sublingual
Know and describe the top atypical antipsychotic with greatest incidence of
prolonged QTc interval. - ANSWER-Ziprasidone (Geodon).
Know which antipsychotics have specific instructions for minimum food intake or
diet restrictions. - ANSWER-Lurasidone (Latuda)
Know an alternative atypical antipsychotic for a patient who has developed
diabetes and has a significant weight gain from treatment with olanzapine. -
ANSWER-Aripiprazole (Abilify)
Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this
week's granulocyte count is less than 500mm3. What is the most appropriate
recommendation for drug therapy? - ANSWER-Discontinue and do not re-start
Know the common effects of smoking along with antipsychotic drug therapy such
as olanzapine. - ANSWER-Decreases the plasma levels of Olanzapine (Zyprexa)
because of its metabolism at CYP450 enzyme.
Know what a painful muscle spasm with neck muscles pulling a patient's head to
the side called and Name a common drug therapy to relieve this symptom. -
ANSWER-Dystonia
Know the role of buspirone in the treatment of anxiety and the recommended
dose and time for onset of action. - ANSWER-Takes 3 to 4 weeks for full effect
Know what medication may be an option for patients noncompliant on
antipsychotics resulting in multiple hospital stays. - ANSWER-Risperdal Consta
(risperidone)
,Know baseline labs and vital measurements tests for the patient who will be
prescribed an antipsychotic such as quetiapine (Seroquel). - ANSWER-Lipid,
Fasting Blood Sugar, Family History **NOT CPK**
Describe common side effects/disadvantages of antihistamines. -
ANSWER-anticholinergic effects
Identify 3-4 disorders/situations when benzodiazepines may be indicated. -
ANSWER-Alcohol withdrawal, Benzodiazepine withdrawal, Acute Agitation,
Panic Attack, Sleep Disorder, Seizures
Describe 2-3 common side effects of atypical antipsychotics. - ANSWER-Weight
gain, Sedation, Metabolic Syndrome
Know and describe the name of long-acting olanzapine and a key adverse side
effect. - ANSWER-Zyprexa Relprevv **Post injection delirium syndrome**
Know and describe screening tools for depression, anxiety, schizophrenia, and
mania symptoms. - ANSWER-Mood Disorder Questionnaire
Be able to describe baseline labs you would want to have prior to ordering
antipsychotics. - ANSWER-CBC, CMP, LFTs, Lipid Panel, HgbA1c, U/A, Urine
Drug Screen **NOT CPK**
What population across the lifespan are most at risk for suicide? How does your
health, gender, and genetics play a role in being at a higher risk for suicide? -
ANSWER-Previous attempts, Substance use, Means and plan, anniversary of a
death of a loved one, **all of the above**
What group/population has the shortest life span? - ANSWER-Black males
Know which organ systems need to be evaluated prior to and at scheduled
intervals when prescribing Depakote (valproate acid). - ANSWER-liver
What medications are used to treat an overdose of a benzodiazepine? -
ANSWER-Flumazenil (Romazicon)
,Know the most common medications used to treat Alzheimer's Disease via
transdermal. - ANSWER-rivastigmine (Exelon)
Know and describe cognitive therapy strategies and how these are used to treat
anxiety. - ANSWER-Keep a diary of symptoms to link symptoms and to work on
reframing
Best medications to treat borderline personality disorder? - ANSWER-No usual
group of medications are used.
What medication is used to treat flu-like symptoms of opioid withdrawal? -
ANSWER-Clonidine
What medication would NOT be used together for treatment resistant
depression? - ANSWER-Monoamine oxidase inhibitors & SSRIs
What would be a lab used to monitor for NMS? - ANSWER-Elevated CPK
, Regis NU641 Adv Clinical Pharmacology
Midterm Exam QUESTIONS AND
CORRECT VERIFIED ANSWERS|GRADED
A
Angina, Coronary Artery Disease, & Migraines - ANSWER-Patients that are at
highest risk for abruptly stopping a beta blocker are those with
Angiotensin-converting enzyme (ACE) inhibitors - ANSWER-The medication that
helps the imbalance between myocardial oxygen supply and myocardial oxygen
demand in the myocardium by increasing the myocardial oxygen supply
improves insulin sensitivity
improves renal hemodynamics
reduce production of angiotensin II - ANSWER-Roles of Angiotensin-converting
enzyme (ACE) inhibitors in DM patients
Activation of the sympathetic nervous system that increases heart rate and
preload - ANSWER-The pathological change that takes place in HF that is not
addressed by ACE inhibitors
blunted coronary artery dilation due to calcified plaque - ANSWER-Reason why
nitro glycerin tablets "do not work well" in patient with hyperlipidemia and angina
age
factoring in the cost to the patient of the medication prescribed -
ANSWER-Clinical judgement in prescribing includes
decreased renal function - ANSWER-Prior to prescribing an ACE inhibitor the NP
should access for
statins - ANSWER-First-line pharmacologic therapy for hyperlipidemia