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ASCP MLS 2025: UPDATED EXAM
WITH VERIFIED SOLUTIONS.
A biomarker with a high specificity: - correct answer -accurately
detects the absence of disease and has few false-positives
Leukemoid Reaction Lab Results: - correct answer -A high white
blood cell count, usually 50-100 x109/L with a left shift is a
common finding in leukemoid reactions. In addition, a key feature
of a leukemoid reaction is a high LAP score
Low LAP score: - correct answer -Paroxysmal Nocturnal
Hemoglobinuria, CML
Tay-Sachs Disease: - correct answer -A rare inherited disorder
characterized by the near-total deficiency of the enzyme N-
acetylbetahexosaminidase A.
Term that means varying degree of leukocytosis with a shift to the
left and occasional nucleated red cell in the peripheral blood: -
correct answer -Leukoerythroblastosis
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Alder-Reilly inclusions: - correct answer -Mucopolysaccarids
Sodium nitroprusside on a urine reagent strip reacts with: - correct
answer -Acetoacetic (diacetic) acid- ketones
Glucose levels whole blood, serum and CSF: - correct answer -
serum>whole blood>CSF
Increased numbers of basophils are often seen in: - correct
answer -Chronic myelocytic leukemia
HLA antibodies are: - correct answer -HLA antibodies are formed
in response to pregnancy, transfusion or transplantation and are
therefore not naturally occurring. They are associated with febrile
nonhemolytic transfusion reactions and TRALI. They are directed
against antigens found on granulocytes and other cells such as
platelets.
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Which of the following combinations is useful for confirming the
presence of extended spectrum beta-lactamases in E coli? -
correct answer -Extended spectrum beta lactamases (ESBL) are
inhibited by clavulanic acid. Confirmatory tests of the presence of
ESBL are based on the enhanced activity of a beta-lactam
antibiotic, usually cefotaxime or ceftazidime, when it is tested with
clavulanic acid compared to the activity of the betalactam tested
alone.
Low PCO2: - correct answer -Represents alkalosis
Low HCO3: - correct answer -Represents acidosis
Seriological marker for:
Rheumatic fever
Wegener's granulomatosis
CREST syndrome
Primary biliary cirrhosis - correct answer -Antimyocardial
antibodies
Antineutrophili antibodies
Anticentromere antibodies
Antimitochondrial antibodies
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Which T cell expresses the CD8 marker and acts specifially to kill
tumor or virally infected cells? - correct answer -T cytotoxic
The most frequent genotype among Rho (D)- negative persons is:
- correct answer -rr
Approximately what percent of the overall population is Rh
negative: - correct answer -15%
Chylomicrons are primarily composed of: - correct answer -
Triglycerides
What conditions increases the risk of HbS polymerization? -
correct answer -Acid pH dehydration, increased level of 2,3-DPG
Markedly elevated 5-hydroxyindole acetic acid (5-HIAA)
determination is presumptive evidence for: - correct answer -
Carcinoid tumor
ASCP MLS 2025: UPDATED EXAM
WITH VERIFIED SOLUTIONS.
A biomarker with a high specificity: - correct answer -accurately
detects the absence of disease and has few false-positives
Leukemoid Reaction Lab Results: - correct answer -A high white
blood cell count, usually 50-100 x109/L with a left shift is a
common finding in leukemoid reactions. In addition, a key feature
of a leukemoid reaction is a high LAP score
Low LAP score: - correct answer -Paroxysmal Nocturnal
Hemoglobinuria, CML
Tay-Sachs Disease: - correct answer -A rare inherited disorder
characterized by the near-total deficiency of the enzyme N-
acetylbetahexosaminidase A.
Term that means varying degree of leukocytosis with a shift to the
left and occasional nucleated red cell in the peripheral blood: -
correct answer -Leukoerythroblastosis
, Page | 2
Alder-Reilly inclusions: - correct answer -Mucopolysaccarids
Sodium nitroprusside on a urine reagent strip reacts with: - correct
answer -Acetoacetic (diacetic) acid- ketones
Glucose levels whole blood, serum and CSF: - correct answer -
serum>whole blood>CSF
Increased numbers of basophils are often seen in: - correct
answer -Chronic myelocytic leukemia
HLA antibodies are: - correct answer -HLA antibodies are formed
in response to pregnancy, transfusion or transplantation and are
therefore not naturally occurring. They are associated with febrile
nonhemolytic transfusion reactions and TRALI. They are directed
against antigens found on granulocytes and other cells such as
platelets.
, Page | 3
Which of the following combinations is useful for confirming the
presence of extended spectrum beta-lactamases in E coli? -
correct answer -Extended spectrum beta lactamases (ESBL) are
inhibited by clavulanic acid. Confirmatory tests of the presence of
ESBL are based on the enhanced activity of a beta-lactam
antibiotic, usually cefotaxime or ceftazidime, when it is tested with
clavulanic acid compared to the activity of the betalactam tested
alone.
Low PCO2: - correct answer -Represents alkalosis
Low HCO3: - correct answer -Represents acidosis
Seriological marker for:
Rheumatic fever
Wegener's granulomatosis
CREST syndrome
Primary biliary cirrhosis - correct answer -Antimyocardial
antibodies
Antineutrophili antibodies
Anticentromere antibodies
Antimitochondrial antibodies
, Page | 4
Which T cell expresses the CD8 marker and acts specifially to kill
tumor or virally infected cells? - correct answer -T cytotoxic
The most frequent genotype among Rho (D)- negative persons is:
- correct answer -rr
Approximately what percent of the overall population is Rh
negative: - correct answer -15%
Chylomicrons are primarily composed of: - correct answer -
Triglycerides
What conditions increases the risk of HbS polymerization? -
correct answer -Acid pH dehydration, increased level of 2,3-DPG
Markedly elevated 5-hydroxyindole acetic acid (5-HIAA)
determination is presumptive evidence for: - correct answer -
Carcinoid tumor
