BIOPHARMACEUTICS (BLUE PACOP) Exam
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Updated 2025
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Terms in this set (300)
Passive diffusion of a drug e. I, II and III c. I and II
molecule across a cell
membrane depends on
the
I. Lipid solubility of the
drug
II. Extent of ionization of
the drug
III. Concentration
difference on either side
of the cell membrane
a. I only d. II and III
b. III only e. I, II and III
c. I and II
,The rate of dissolution of a a. I only
weakly acidic drug may be
increased by
I. Increasing the pH of the
medium
II. Increasing the particle
size of the solid drug
III. Increasing the viscosity
of the medium
a. I only d. II and III
b. III only e. I, II and III
c. I and II
The initial degradation of b. First pass metabolism
drug by liver enzymes
after oral administration of
a drug is known:
a. Enzymatic degradation
d. Fick's degradation
b. First pass metabolism e.
absolute bioavailability
c. Relative bioavailability
Which of the following e. I,II and III
parameters can evaluate
bio equivalency of drugs?
I. Time to reach peak
concentration
II. AUC
III. Concentration of drug
at plateau level
a. I only d. II only
b. I and II only e. I,II and III
c. II and III only
,The following statements a. Amorphous form is more soluble than crystallized
are not true except: form d. hydrates are equivalent to solvates
a. Amorphous form is
more soluble than
crystallized form
b. Hydrous form is more
soluble then anhydrous
c. Polymorph is more
soluble then
enantiomorph
d. hydrates are equivalent
to solvates
e. none of the above
A measure of the quantity b. AUC
of drug in the body:
a. Vd d. Ko/w
b. AUC e. t1/2
c. pH
Study of what the body b. Pharmacokinetics
does to the drug:
a. Biopharmaceutics d.
pharmacology
b. Pharmacokinetics e.
pharmaceutics
c. Pharmacodynamics
, Two different oral b. Deliver the same total amount of drug
formulations of the same
drug having equal areas
under respective serum-
concentration time curves
a. Deliver the same total
amount of drug
b. Deliver the same total
amount of drug
c. Are bioequivalent by
definition
d. are bioequivalent if they
both meet to the body
and are, therefore
bioequivalent USP
disintegration standards
e. are therapeutically
equivalent in the body but
are not necessarily
bioequivalent
Gastric emptying rate is d. hunger
slowed down by all of the
ff. except:
a. Vigorous exercise d.
hunger
b. Fatty foods e. lying on
the left side
c. Hot meals
An absorption mechanism e. vesicular
for Sabin pollo vaccine:
a. Passive diffusion d.
convective transport
b. Ion-pair transport e.
vesicular
c. Active transport
Questions and Answers 100% Pass |Verified and
Updated 2025
Save
Terms in this set (300)
Passive diffusion of a drug e. I, II and III c. I and II
molecule across a cell
membrane depends on
the
I. Lipid solubility of the
drug
II. Extent of ionization of
the drug
III. Concentration
difference on either side
of the cell membrane
a. I only d. II and III
b. III only e. I, II and III
c. I and II
,The rate of dissolution of a a. I only
weakly acidic drug may be
increased by
I. Increasing the pH of the
medium
II. Increasing the particle
size of the solid drug
III. Increasing the viscosity
of the medium
a. I only d. II and III
b. III only e. I, II and III
c. I and II
The initial degradation of b. First pass metabolism
drug by liver enzymes
after oral administration of
a drug is known:
a. Enzymatic degradation
d. Fick's degradation
b. First pass metabolism e.
absolute bioavailability
c. Relative bioavailability
Which of the following e. I,II and III
parameters can evaluate
bio equivalency of drugs?
I. Time to reach peak
concentration
II. AUC
III. Concentration of drug
at plateau level
a. I only d. II only
b. I and II only e. I,II and III
c. II and III only
,The following statements a. Amorphous form is more soluble than crystallized
are not true except: form d. hydrates are equivalent to solvates
a. Amorphous form is
more soluble than
crystallized form
b. Hydrous form is more
soluble then anhydrous
c. Polymorph is more
soluble then
enantiomorph
d. hydrates are equivalent
to solvates
e. none of the above
A measure of the quantity b. AUC
of drug in the body:
a. Vd d. Ko/w
b. AUC e. t1/2
c. pH
Study of what the body b. Pharmacokinetics
does to the drug:
a. Biopharmaceutics d.
pharmacology
b. Pharmacokinetics e.
pharmaceutics
c. Pharmacodynamics
, Two different oral b. Deliver the same total amount of drug
formulations of the same
drug having equal areas
under respective serum-
concentration time curves
a. Deliver the same total
amount of drug
b. Deliver the same total
amount of drug
c. Are bioequivalent by
definition
d. are bioequivalent if they
both meet to the body
and are, therefore
bioequivalent USP
disintegration standards
e. are therapeutically
equivalent in the body but
are not necessarily
bioequivalent
Gastric emptying rate is d. hunger
slowed down by all of the
ff. except:
a. Vigorous exercise d.
hunger
b. Fatty foods e. lying on
the left side
c. Hot meals
An absorption mechanism e. vesicular
for Sabin pollo vaccine:
a. Passive diffusion d.
convective transport
b. Ion-pair transport e.
vesicular
c. Active transport
