Pharm II - men's health Exam
1. benign prostatic obstruction is associated with: lower urinary tract symptoms
2. what is the active form of testosterone: dihydrotestosterone
3. static factors of BPH: obstruction due to hyperplastic tissue
4. Dynamic factors of BPH: increased smooth muscle tone within prostatic bladder neck
5. obstructive symptoms of BPH: weak stream
dribbling
straining
intermittency
incomplete void/bladder feels full
hesitancy
6. irritative symptoms of BPH (longstanding obstruction): frequency
nocturia
urgency
incontinence
1/5
, 7. progression of BPH: BPH --> benign prostatic enlargement --> benign prostatic obstruction
8. lifestyle modifications for BPH: minimize caffeine and alcohol
voiding habits
weight loss
9. meds that aggravate BPH (make it worse): alpha adrenergic agonists (decongestants)
anticholinergics (antihistamines, tricyclic antidepressants, antispasmodics, phenothiazines)
diuretics
testosterone
10. which meds for BPH relax prostatic smooth muscle: alpha-1 antagonists
phosphodiesterase inhibitors
11. which meds for BPH interfere with testosterone's stimulatory effect: 5a-reduc-
tase inhibitors
12. which meds for BPH relax the bladder detrusor muscle: anticholinergics
mirabegron
13. alpha-1 antagonists MOA: Relax smooth muscle in the prostate and bladder neck
2/5
1. benign prostatic obstruction is associated with: lower urinary tract symptoms
2. what is the active form of testosterone: dihydrotestosterone
3. static factors of BPH: obstruction due to hyperplastic tissue
4. Dynamic factors of BPH: increased smooth muscle tone within prostatic bladder neck
5. obstructive symptoms of BPH: weak stream
dribbling
straining
intermittency
incomplete void/bladder feels full
hesitancy
6. irritative symptoms of BPH (longstanding obstruction): frequency
nocturia
urgency
incontinence
1/5
, 7. progression of BPH: BPH --> benign prostatic enlargement --> benign prostatic obstruction
8. lifestyle modifications for BPH: minimize caffeine and alcohol
voiding habits
weight loss
9. meds that aggravate BPH (make it worse): alpha adrenergic agonists (decongestants)
anticholinergics (antihistamines, tricyclic antidepressants, antispasmodics, phenothiazines)
diuretics
testosterone
10. which meds for BPH relax prostatic smooth muscle: alpha-1 antagonists
phosphodiesterase inhibitors
11. which meds for BPH interfere with testosterone's stimulatory effect: 5a-reduc-
tase inhibitors
12. which meds for BPH relax the bladder detrusor muscle: anticholinergics
mirabegron
13. alpha-1 antagonists MOA: Relax smooth muscle in the prostate and bladder neck
2/5
