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ANP 242 - Morefield Case Study: Endocrine Due: By Dec 1, 2020 Upload to Canvas To answer the questions, use your book, notes and the internet. Use the internet minimally. I do not want to see a lot of technical and clinical terminology that has

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ANP 242 - Morefield Case Study: Endocrine Due: By Dec 1, 2020 Upload to Canvas To answer the questions, use your book, notes and the internet. Use the internet minimally. I do not want to see a lot of technical and clinical terminology that has been taken straight from the internet or books. Be cautious that you do not plagiarize. I am looking for logical thinking to answer the questions. Getting the exact answer is not the goal, but instead to approach physiological problems in a systematical and methodical manner. Main thing is to explain/justify your answers to the questions. Please type the answers and turn in a hard copy. Around 1 – 3pages typed is fairly typical. Avoid me asking “why” or “how” in response to your answers. I don’t care how you format your answers or the document. Just make sure I can easily read and understand your answers. Case Presentation Mr. Tripson, a 70-year old male was brought into the ER in a comatose state and has yet to come out of it. It is obvious that he suffered severe head trauma – his scalp was badly lacerated, and he has an impacted skull fracture. His initial lab tests (blood and urine) were within normal limits. His fracture was repaired and the following orders (and others) were given: Check Qh (every hour) and record; vital signs, spontaneous behavior, level of responsiveness to stimulation, movements, speech, pupil size and reaction to light Turn patient Q4h and maintain meticulous skin care and dryness. On the second day of his hospitalization, the aide reports that Mr. Tripson is breathing irregularly, his skin is dry and flaccid, and that she has emptied his urine reservoir several times during the day. Mr. Tripson is found to be losing huge amounts of water in urine (polyuria) and the volume lost is being routinely replaced (via IV line). Upon receiving this information, the physician ordered: Blood and urine tests Strict I&O (fluid intake and output recording) Mr. Tripson’s lab results show: Plasma sodium = 149mEq/L Plasma osmolality = 308mOsm/kg Plasma glucose = 85mg/dl Plasma ketone = 1mg/dl Urine osmolality = 200mOsm/kg Urine glucose = negative Urine ketones = negative Relative to these findings answers the following: 1. Why are these lab tests ordered? What is the physician trying to determine or rule out? What is the significance of these test results? Are these results normal, low or high? Note: you will have to do a bit of research/reading on lab results and how glucose and ketones are related physiologically and briefly explain to fully be able to answer the question. 2. What would you say Mr. Tripson’s hormonal problem is and what do you think caused it? (hint: problem is with only one hormone) Make sure you use facts and evidence from Mr. Tripson’s case to support your diagnosis. 3. Discuss how this hormone normally works in the body to regulate fluid levels. What causes this hormone to be released normally, from where, and what does it do? 4. In what ways is Mr. Tripson’s condition similar to diabetes mellitus? In what ways do they differ? How does the mechanism by which diuresis occurs with Mr. Tripson’s condition differ from that which occurs in diabetes mellitus? 5. Is Mr. Tripson’s hormonal problem life threatening? Explain why or why it isn’t. How will his condition be treated or managed?

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