Maryville University: NURS615 Pharm
Exam 1 Questions with 100% Correct
Answers
Clinical Judgement Correct Answer: Conclusion/opinion at which a nurse
arrives following a process of observation, reflection, & analysis of observable or
available information or data.
*must gather data to make diagnosis, must have diagnosis to select and start
treatment
WHO 6-Step Model of Rational Prescribing Correct Answer: 1. Define patient's
problem (diagnose)
2. Specify the therapeutic objective (goal)
3. Choose treatment
4. Start treatment
5. Educate the patient
6. Monitor the effectiveness
Criteria for choosing an effective drug
"I Can PresCribe A Drug" Mnemonic Correct Answer: I=indication
C=contraindication
P=precautions
,C=cost/compliance
E=efficacy
A=adverse effects
D=dose/duration/direction
Role of FDA Correct Answer: Ensures the safety, efficacy, and security of human
and veterinary drugs, biological products, and medical devices. As well as food,
cosmetics, and products that emit radiation.
What is the role of the FDA in regard to supplements and vitamins? Correct
Answer: Does NOT protect or ensure the safety of supplements and vitamins.
They have certain rules, but they aren't as stringent like they are for drugs.
What can St. John's wort interact with? Correct Answer: SSRI, CNS drugs, MAOI,
SSNRI, steroids, caffeine, and anticoagulants.
Off-label prescribing Correct Answer: medication is being used in a manner not
specified in the FDAs approved packaging label/insert.
*different route, dose, or indication
Pharmacotherapeutics Correct Answer: study of therapeutic uses and effects of
drugs. Beneficial and adverse drug reactions.
Pharmacodynamics Correct Answer: what the drug does to the body
Agonist Correct Answer: binds to a receptor & produces a response/stimulates
(full activation)
Antagonist Correct Answer: Binds & blocks activity (no activation)
, Can a drug be an agonist and antagonist? Correct Answer: Yes. In this case,
they do both actions to have less activation, versus full or no activation.
Pharmacokinetics Correct Answer: what the body does to the drug (ADME)
What is ADME in pharmacokinetics? Correct Answer: absorption, distribution,
metabolism, excretion
Absorption Correct Answer: first step, occurs after medication administration
What does absorption depend on? Correct Answer: routes of administration, pH
and membrane penetration
What percentage of rectal drugs go through first-pass metabolism? Correct
Answer: 50%
Membrane penetration involves what? Correct Answer: lipid solubility and
ionization
How does pH affect absorption? Correct Answer: If the pH of the stomach is
altered, in oral medication administration, the medication can be absorbed too
soon or not soon enough.
Why can't you crush enteric coated medications? Correct Answer: This interferes
with absorption, it will not absorb where intended.
Ionization Correct Answer: the charge of the molecule/drug.
Ionized = charged (polar)
non-ionized = uncharged (non-polar)
Lipophilic Correct Answer: *Lipid loving, uncharged (non-polar/non-ionized),
small in size.
Exam 1 Questions with 100% Correct
Answers
Clinical Judgement Correct Answer: Conclusion/opinion at which a nurse
arrives following a process of observation, reflection, & analysis of observable or
available information or data.
*must gather data to make diagnosis, must have diagnosis to select and start
treatment
WHO 6-Step Model of Rational Prescribing Correct Answer: 1. Define patient's
problem (diagnose)
2. Specify the therapeutic objective (goal)
3. Choose treatment
4. Start treatment
5. Educate the patient
6. Monitor the effectiveness
Criteria for choosing an effective drug
"I Can PresCribe A Drug" Mnemonic Correct Answer: I=indication
C=contraindication
P=precautions
,C=cost/compliance
E=efficacy
A=adverse effects
D=dose/duration/direction
Role of FDA Correct Answer: Ensures the safety, efficacy, and security of human
and veterinary drugs, biological products, and medical devices. As well as food,
cosmetics, and products that emit radiation.
What is the role of the FDA in regard to supplements and vitamins? Correct
Answer: Does NOT protect or ensure the safety of supplements and vitamins.
They have certain rules, but they aren't as stringent like they are for drugs.
What can St. John's wort interact with? Correct Answer: SSRI, CNS drugs, MAOI,
SSNRI, steroids, caffeine, and anticoagulants.
Off-label prescribing Correct Answer: medication is being used in a manner not
specified in the FDAs approved packaging label/insert.
*different route, dose, or indication
Pharmacotherapeutics Correct Answer: study of therapeutic uses and effects of
drugs. Beneficial and adverse drug reactions.
Pharmacodynamics Correct Answer: what the drug does to the body
Agonist Correct Answer: binds to a receptor & produces a response/stimulates
(full activation)
Antagonist Correct Answer: Binds & blocks activity (no activation)
, Can a drug be an agonist and antagonist? Correct Answer: Yes. In this case,
they do both actions to have less activation, versus full or no activation.
Pharmacokinetics Correct Answer: what the body does to the drug (ADME)
What is ADME in pharmacokinetics? Correct Answer: absorption, distribution,
metabolism, excretion
Absorption Correct Answer: first step, occurs after medication administration
What does absorption depend on? Correct Answer: routes of administration, pH
and membrane penetration
What percentage of rectal drugs go through first-pass metabolism? Correct
Answer: 50%
Membrane penetration involves what? Correct Answer: lipid solubility and
ionization
How does pH affect absorption? Correct Answer: If the pH of the stomach is
altered, in oral medication administration, the medication can be absorbed too
soon or not soon enough.
Why can't you crush enteric coated medications? Correct Answer: This interferes
with absorption, it will not absorb where intended.
Ionization Correct Answer: the charge of the molecule/drug.
Ionized = charged (polar)
non-ionized = uncharged (non-polar)
Lipophilic Correct Answer: *Lipid loving, uncharged (non-polar/non-ionized),
small in size.
