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Summary ASCP Board of Certification MLS Practice Exam (Latest 2025 / 2026) Tested Questions with Revised Answers, (A+ Guarantee)

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ASCP Board of Certification MLS Practice Exam (Latest 2025 / 2026) Tested Questions with Revised Answers, (A+ Guarantee)

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ASCP Board Of Certification MLS Prac
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ASCP Board of Certification MLS Prac

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ASCP Board of Certification MLS Practice
Exam (Latest ) Tested Questions
with Revised Answers, (A+ Guarantee)
Clinically insignificant cold antibodies antibodies - CORRECT ANSWERS The immediate spin
phase of an indirect antiglobulin test (antibody screen and antibody identification) could most likely lead
to the detection of what?

Micosporum canis - CORRECT ANSWERS

Albumin - CORRECT ANSWERS Which analyte measurement is used to detect early
nephropathy in a diabetic patient?

32 grams - CORRECT ANSWERS In order to correctly prepare a 4 M solution of NaOH, how
many grams need to be added to 200 mL of solution? (GMW NaOH =40 g)

Russell bodies - CORRECT ANSWERS What are the globular inclusions in this cell?

This represents normal kidney function - CORRECT ANSWERS A urine concentration test was
performed on a patient after a fluid intake deprivation period with the following findings:
After 12 hours Urine Osmolality = 850 mOsm/KgAfter 16 hours Urine Osmolality = 850 mOsm/Kg
What do these results indicate?

Nucleolar - CORRECT ANSWERS This antinuclear antibody (ANA) test is viewed using
fluorescent microscopy, which pattern is this?

Corynebacterium jeikeium - CORRECT ANSWERS Which species of Corynebacterium is
lipophilic?

Systematic error - CORRECT ANSWERS If a commercial lyophilized reagent is diluted using
slightly more distilled water than indicated, what type of error will occur?

Hereditary spherocytosis - CORRECT ANSWERS The autohemolysis test is MOST useful in the
diagnosis of which condition?

Clinical Chemistry - CORRECT ANSWERS Which clinical laboratory department performs the
most tests?

Quantitative fecal fat - CORRECT ANSWERS Which test requires a 72-hour stool (fecal)
collection?

There is no discernable pattern - CORRECT ANSWERS Which antinuclear antibody (ANA)
pattern is seen in the image on the right, which represents the result of an ANA test viewed using
fluorescent microscopy?

A - CORRECT ANSWERS From the IgG molecule illustration, which region is the heavy chain?

,Lactobacillus species - CORRECT ANSWERS From the choices listed below, which organism is
classified as an aerotolerant anaerobe?

Clostridium novyi
Staphylococcus aureus
Lactobacillus species
Neisseria species

Efficiency - CORRECT ANSWERS The number of patients correctly diagnosed for the disease or
not having the disease is defined as:

Cannot report - CORRECT ANSWERS A manual white blood cell count was performed by the
hematology technologist. The cell counts for both sides were 99 and 164 respectively. All nine large
squares were counted on each side. The dilution for this kit was pre-measured at 1:100. What should
the technologist report as the white cell count?

Candida glabrata - CORRECT ANSWERS This species of Candida accounts for around 20 percent
of urinary yeast isolates.

Positive DAT - CORRECT ANSWERS Which finding best distinguishes immune hemolytic anemia
from other hemolytic anemias?

Phosphorus - CORRECT ANSWERS Which analyte shows no difference between capillary and
venous values?

Amylase - CORRECT ANSWERS Which blood test is used to determine acute pancreatitis?

Anti-Leb - CORRECT ANSWERS If detected in antibody screen testing, which of the following
antibodies is NOT considered clinically significant in prenatal patients?

Brown/black - CORRECT ANSWERS Homogentisic acid in urine will cause urine to be which
color?

Type IV Cell mediated hypersensitivity (T-cell dependent) - CORRECT ANSWERS The type of
hypersensitivity reaction associated with macrophage activation, cytokine-mediated inflammation is:

Reliability - CORRECT ANSWERS The degree in which a measure is consistent in producing the
same results when measuring the same analyte is called:

Lymphocytes - CORRECT ANSWERS A college student is treated in the hospital for suspected
meningitis. Which cells should be identified in the cerebrospinal fluid (CSF) report for the cytospin field
that is shown?

Sodium - CORRECT ANSWERS What contributes most to serum osmolality:

, Lesions caused by deposition of antigen-antibody immune complexes - CORRECT ANSWERS
Identify a characteristic of an organ-non specific disorder that distinguishes it from an organ specific
disorder.

ABO/Rh, DAT and/or antibody screening are NOT routinely performed in this scenario. - CORRECT
ANSWERS What is the recommended routine testing to be performed on a newborn of a group
B Rh positive female?

Microcytic, hypochromic - CORRECT ANSWERS A patient has the following hematology test
results. Classify the anemia:
Hgb = 8.1 g/dL
Hct = 31%
RBC = 4.0 x 1012/L

Bacillus anthracis - CORRECT ANSWERS Which organism displays the characteristic "Medusa
head" on 5% sheep blood agar (SBA) after 18 hours of incubation at 35°C?

Estimated average glucose - CORRECT ANSWERS Recently the American Diabetes Association
(ADA) recommended reporting which of these values in order to correlate with hemoglobin A1C
(HbA1C) as a further indicator of glycemic control?

Myeloblast - CORRECT ANSWERS Which of the following cells are considered abnormal and
clinically significant on a CSF differential?

Ependymal
Myeloblast
Pia arachnoid mesothelial
Choroidal cells

Affinity - CORRECT ANSWERS The name of a reaction between a single antigenic determinant
and an individual combining site is:

Increased testing volume - CORRECT ANSWERS A new clinic in the area is sending a very large
number of additional chemistry tests to the laboratory. The existing chemistry instrument is only 2 years
old and works well, however, there is a need to acquire a high throughput instrument. What is the
appropriate "Justification Category?"

AB negative and AB positive only - CORRECT ANSWERS Which fresh frozen plasma ABO types
would be suitable for transfusion to an AB negative patient?

Streptococcus pneumoniae - CORRECT ANSWERS The most frequent cause of bacterial
meningitis in adults and in children is:

EIA or indirect immunoflourescence - CORRECT ANSWERS Which serological test would be
used for the diagnosis of Q-fever?

Positive because conjugated bilirubin is present and is excreted by the kidneys. - CORRECT ANSWERS
When a patient has a bile duct obstruction, the bilirubin test portion of the reagent strip is:

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