Lehne's Pharmacology Exam 1 Ch 1-
6 Exam Updated 2025/2026 Exam
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Consequences of drug interaction - ANSWER ✓ 1. drug intensifies other drug
2.one drug reduces effect of another
3.new response may appear
Example of intensified therapeutic effect - ANSWER ✓ +Ex: Sulbactum and
ampicillin, sulbactum inhibits the liver enzymes that would otherwise deactivate
ampicillin, therefore allowing ampicillin to work.
Intensified adverse effect interaction example - ANSWER ✓ Aspirin and Warfarin
Both anticoagulants and increase bleeding risk
Example of an intended and desired response for using multiple drugs: -
ANSWER ✓ Hypertension multi drug use
Give an example of reduced therapeutic effects for propanolol and albuterol: -
ANSWER ✓ Propanolol blocks the effects of albuterol
Give an example of reduced adverse effects: - ANSWER ✓ Naloxone used to treat
morphine OD
Mechanical drug-drug interaction - ANSWER ✓ Usually direct physical/chemical
interactions occur in IV and render both drugs ineffective
What is an example of a drug-drug interaction affecting the same organ?? -
ANSWER ✓ Isonazid taken with rifampin for TB
both=hepatotoxic
, Increase liver toxicity chances
What is the rule of thumb for giving 2 medications? - ANSWER ✓ Don't give two
meds that affect the same organ
FOR TB THIS IS NECESSARY THOUGH
Food-drug interactions - ANSWER ✓ result from the physiologic incompatibility
of therapeutic drugs and food consumed by a patient
Food drug interactions can affect... - ANSWER ✓ -absorption and predicatability
-duration of effects
-enhance therepuetic effects
- increase toxicity
-decrease therepuetic responses
What does Ca2+ rich food or medications do with tetracycline?? - ANSWER ✓
Reduces the effectiveness
What is digoxin effected by?(food)(lab) - ANSWER ✓ high fiber foods,
potassium levels
What can grapefruit juice do? - ANSWER ✓ greatly inhibit metabolism thereby
raising blood levels.
_______ causes a 406% increase in blood levels of felodipine, lovastatin,
cyclosporine, midazolam and many other drugs. EFFECTS P450 system. -
ANSWER ✓ Grapefruit juice
Monomine oxidase (depression med) when combined with foods rich in
tyramine(yeasty foods), can cause.... - ANSWER ✓ near fatal high BP
What can vitamin K directly do to warfarin(anticoagulant) - ANSWER ✓ reduce
its effects
What are the components of a complete drug order? - ANSWER ✓ Date/time
order was written
Medication Name
Dosage Strength
6 Exam Updated 2025/2026 Exam
Questions with Correct
Answers||Already Graded A+||
100% Guaranteed Pass||<<Newest
Version>>
Consequences of drug interaction - ANSWER ✓ 1. drug intensifies other drug
2.one drug reduces effect of another
3.new response may appear
Example of intensified therapeutic effect - ANSWER ✓ +Ex: Sulbactum and
ampicillin, sulbactum inhibits the liver enzymes that would otherwise deactivate
ampicillin, therefore allowing ampicillin to work.
Intensified adverse effect interaction example - ANSWER ✓ Aspirin and Warfarin
Both anticoagulants and increase bleeding risk
Example of an intended and desired response for using multiple drugs: -
ANSWER ✓ Hypertension multi drug use
Give an example of reduced therapeutic effects for propanolol and albuterol: -
ANSWER ✓ Propanolol blocks the effects of albuterol
Give an example of reduced adverse effects: - ANSWER ✓ Naloxone used to treat
morphine OD
Mechanical drug-drug interaction - ANSWER ✓ Usually direct physical/chemical
interactions occur in IV and render both drugs ineffective
What is an example of a drug-drug interaction affecting the same organ?? -
ANSWER ✓ Isonazid taken with rifampin for TB
both=hepatotoxic
, Increase liver toxicity chances
What is the rule of thumb for giving 2 medications? - ANSWER ✓ Don't give two
meds that affect the same organ
FOR TB THIS IS NECESSARY THOUGH
Food-drug interactions - ANSWER ✓ result from the physiologic incompatibility
of therapeutic drugs and food consumed by a patient
Food drug interactions can affect... - ANSWER ✓ -absorption and predicatability
-duration of effects
-enhance therepuetic effects
- increase toxicity
-decrease therepuetic responses
What does Ca2+ rich food or medications do with tetracycline?? - ANSWER ✓
Reduces the effectiveness
What is digoxin effected by?(food)(lab) - ANSWER ✓ high fiber foods,
potassium levels
What can grapefruit juice do? - ANSWER ✓ greatly inhibit metabolism thereby
raising blood levels.
_______ causes a 406% increase in blood levels of felodipine, lovastatin,
cyclosporine, midazolam and many other drugs. EFFECTS P450 system. -
ANSWER ✓ Grapefruit juice
Monomine oxidase (depression med) when combined with foods rich in
tyramine(yeasty foods), can cause.... - ANSWER ✓ near fatal high BP
What can vitamin K directly do to warfarin(anticoagulant) - ANSWER ✓ reduce
its effects
What are the components of a complete drug order? - ANSWER ✓ Date/time
order was written
Medication Name
Dosage Strength
